NDC80 kinetochore complex component (Q21109472)

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mammalian protein found in Homo sapiens
  • HsHec1
  • kinetochore associated 2
  • highly expressed in cancer protein
  • kinetochore protein Hec1
  • retinoblastoma-associated protein HEC
  • NDC80
  • NDC80 kinetochore complex component homolog
  • kinetochore-associated protein 2
  • highly expressed in cancer, rich in leucine heptad repeats
  • NDC80 homolog, kinetochore complex component
  • kinetochore protein NDC80 homolog
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Language Label Description Also known as
English
NDC80 kinetochore complex component
mammalian protein found in Homo sapiens
  • HsHec1
  • kinetochore associated 2
  • highly expressed in cancer protein
  • kinetochore protein Hec1
  • retinoblastoma-associated protein HEC
  • NDC80
  • NDC80 kinetochore complex component homolog
  • kinetochore-associated protein 2
  • highly expressed in cancer, rich in leucine heptad repeats
  • NDC80 homolog, kinetochore complex component
  • kinetochore protein NDC80 homolog

Statements

molecular function
protein binding
determination method
IPI
14 references
retrieved
9 May 2019
stated in
Identification of two novel components of the human NDC80 kinetochore complex
GOA
curator
UniProt
UniProt protein ID
O14777
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14777
determination method
IPI
retrieved
9 May 2019
stated in
The functional region of CENP-H interacts with the Nuf2 complex that localizes to centromere during mitosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14777
determination method
IPI
retrieved
9 May 2019
stated in
CELL DIVISION CYCLE. Kinetochore attachment sensed by competitive Mps1 and microtubule binding to Ndc80C.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14777
determination method
IPI
retrieved
9 May 2019
stated in
The conserved KMN network constitutes the core microtubule-binding site of the kinetochore
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14777
determination method
IPI
retrieved
9 May 2019
stated in
Hec1 sequentially recruits Zwint-1 and ZW10 to kinetochores for faithful chromosome segregation and spindle checkpoint control
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14777
determination method
IPI
retrieved
9 May 2019
stated in
Towards a proteome-scale map of the human protein–protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14777
determination method
IPI
retrieved
9 May 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14777
determination method
IPI
retrieved
9 May 2019
stated in
ZW10 links mitotic checkpoint signaling to the structural kinetochore.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14777
determination method
IPI
retrieved
9 May 2019
stated in
Recruitment of the human Cdt1 replication licensing protein by the loop domain of Hec1 is required for stable kinetochore-microtubule attachment
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14777
determination method
IPI
retrieved
9 May 2019
stated in
Architecture of the human ndc80-hec1 complex, a critical constituent of the outer kinetochore
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14777
determination method
IPI
retrieved
9 May 2019
stated in
Systematic analysis of human protein complexes identifies chromosome segregation proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14777
determination method
IPI
retrieved
9 May 2019
stated in
Identification of two novel components of the human NDC80 kinetochore complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14777
determination method
IPI
retrieved
9 May 2019
stated in
A human interactome in three quantitative dimensions organized by stoichiometries and abundances
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14777
determination method
IPI
retrieved
9 May 2019
stated in
Recruitment of the human Cdt1 replication licensing protein by the loop domain of Hec1 is required for stable kinetochore-microtubule attachment
GOA
curator
Critical Assessment of Protein Function Annotation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14777
determination method
IPI
cell component
biological process

Identifiers

 
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