Eukaryotic translation initiation factor 2B subunit gamma (Q21108564)

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mammalian protein found in Homo sapiens

EIF2B3
eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
translation initiation factor eIF-2B subunit gamma
eIF-2B GDP-GTP exchange factor subunit gamma

Language	Label	Description	Also known as
English	Eukaryotic translation initiation factor 2B subunit gamma	mammalian protein found in Homo sapiens	EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa translation initiation factor eIF-2B subunit gamma eIF-2B GDP-GTP exchange factor subunit gamma

Statements

1 reference

13 November 2019

UniProt protein ID

nucleotide-diphospho-sugar transferases

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NR50

Nucleotidyl transferase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

nucleotidyltransferase activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NR50

determination method

translation factor activity, RNA binding

determination method

1 reference

8 April 2019

Identification of eIF2Bgamma and eIF2gamma as cofactors of hepatitis C virus internal ribosome entry site-mediated translation using a functional genomics approach

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NR50

determination method

protein binding

determination method

1 reference

8 April 2019

Mutations linked to leukoencephalopathy with vanishing white matter impair the function of the eukaryotic initiation factor 2B complex in diverse ways

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NR50

determination method

translation initiation factor activity

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NR50

determination method

8 April 2019

An efficient mammalian cell-free translation system supplemented with translation factors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NR50

determination method

8 April 2019

Identification of eIF2Bgamma and eIF2gamma as cofactors of hepatitis C virus internal ribosome entry site-mediated translation using a functional genomics approach

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NR50

determination method

guanyl-nucleotide exchange factor activity

determination method

3 references

8 April 2019

Decreased guanine nucleotide exchange factor activity in eIF2B-mutated patients

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NR50

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NR50

determination method

8 April 2019

Characterization of the mammalian initiation factor eIF2B complex as a GDP dissociation stimulator protein

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NR50

determination method

determination method

1 reference

8 April 2019

Characterization of the mammalian initiation factor eIF2B complex as a GDP dissociation stimulator protein

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NR50

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NR50

determination method

eukaryotic translation initiation factor 2B complex

determination method

3 references

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NR50

determination method

8 April 2019

Mutations linked to leukoencephalopathy with vanishing white matter impair the function of the eukaryotic initiation factor 2B complex in diverse ways

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NR50

determination method

8 April 2019

Characterization of the mammalian initiation factor eIF2B complex as a GDP dissociation stimulator protein

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NR50

determination method

biological process

oligodendrocyte development

determination method

1 reference

8 April 2019

The life and death of oligodendrocytes in vanishing white matter disease

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NR50

determination method

response to heat

determination method

3 references

8 April 2019

A severe variant of childhood ataxia with central hypomyelination/vanishing white matter leukoencephalopathy related to EIF21B5 mutation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NR50

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NR50

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NR50

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NR50

determination method

hippocampus development

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NR50

determination method

protein biosynthesis

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NR50

determination method

translational initiation

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NR50

determination method

8 April 2019

An efficient mammalian cell-free translation system supplemented with translation factors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NR50

determination method

8 April 2019

Identification of eIF2Bgamma and eIF2gamma as cofactors of hepatitis C virus internal ribosome entry site-mediated translation using a functional genomics approach

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NR50

determination method

T cell receptor signaling pathway

determination method

1 reference

8 April 2019

T-cell activation leads to rapid stimulation of translation initiation factor eIF2B and inactivation of glycogen synthase kinase-3

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NR50

determination method

Nucleotidyl transferase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NR50

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000353575

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000353575

ENSP00000361257

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000361257

ENSP00000483996

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000483996

ENSP00000396985

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000396985

ENSP00000485842

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000485842

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