minichromosome maintenance complex component 5 (Q21107563)

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mammalian protein found in Homo sapiens

DNA replication licensing factor MCM5
minichromosome maintenance deficient 5 (cell division cycle 46)
CDC46 homolog
MCM5 minichromosome maintenance deficient 5, cell division cycle 46
MCM5
P1-CDC46

Language	Label	Description	Also known as
English	minichromosome maintenance complex component 5	mammalian protein found in Homo sapiens	DNA replication licensing factor MCM5 minichromosome maintenance deficient 5 (cell division cycle 46) CDC46 homolog MCM5 minichromosome maintenance deficient 5, cell division cycle 46 MCM5 P1-CDC46

Statements

1 reference

13 November 2019

UniProt protein ID

Nucleic acid-binding, OB-fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P33992

DNA replication licensing factor Mcm5

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P33992

P-loop containing nucleoside triphosphate hydrolase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P33992

MCM N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

MCM OB domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

MCM domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Mini-chromosome maintenance, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

nucleotide binding

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

DNA helicase activity

determination method

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P33992&geneProductId=UniProtKB:P33992

determination method

DNA replication origin binding

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

chromatin binding

determination method

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P33992&geneProductId=UniProtKB:P33992

determination method

protein binding

determination method

11 references

9 May 2019

Identification and functional analysis of a novel cyclin e/cdk2 substrate ankrd17

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

9 May 2019

Analysis of interaction partners of H4 histone by a new proteomics approach

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

9 May 2019

Essential role of phosphorylation of MCM2 by Cdc7/Dbf4 in the initiation of DNA replication in mammalian cells

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

9 May 2019

Identification and characterization of a novel component of the human minichromosome maintenance complex

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

9 May 2019

Epidermal growth factor receptor potentiates MCM7-mediated DNA replication through tyrosine phosphorylation of Lyn kinase in human cancers

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

9 May 2019

A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

9 May 2019

Self-assembling protein microarrays

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

9 May 2019

Interaction of human minichromosome maintenance protein-binding protein with minichromosome maintenance 2-7

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

9 May 2019

Interactions of the human MCM-BP protein with MCM complex components and Dbf4

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

9 May 2019

L3MBTL1 polycomb protein, a candidate tumor suppressor in del(20q12) myeloid disorders, is essential for genome stability

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

9 May 2019

Human Mcm proteins at a replication origin during the G1 to S phase transition

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

hydrolase activity

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

helicase activity

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

single-stranded DNA binding

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

single-stranded DNA helicase activity

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

3'-5' DNA helicase activity

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

determination method

1 reference

17 October 2017

Defining the membrane proteome of NK cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P33992&geneProductId=UniProtKB:P33992

determination method

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

determination method

1 reference

9 May 2019

Defining the membrane proteome of NK cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

determination method

4 references

9 May 2019

Coding sequence and chromosome mapping of the human gene (CDC46) for replication protein hCdc46/Mcm5

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

determination method

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

9 May 2019

Identification and characterization of a novel component of the human minichromosome maintenance complex

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

biological process

determination method

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P33992&geneProductId=UniProtKB:P33992

determination method

DNA replication

determination method

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

9 May 2019

Coding sequence and chromosome mapping of the human gene (CDC46) for replication protein hCdc46/Mcm5

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

DNA duplex unwinding

determination method

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

DNA replication initiation

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

G1/S transition of mitotic cell cycle

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

double-strand break repair via break-induced replication

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

pre-replicative complex assembly involved in nuclear cell cycle DNA replication

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33992

determination method

Identifiers

MeSH descriptor ID

subject named as

Minichromosome Maintenance Complex Component 5

0 references

D08.811.277.040.025.159.186.500

0 references

D08.811.399.340.186.500

0 references

D12.776.167.409.500

0 references

D12.776.660.235.500.500

0 references

D12.776.664.235.750.500

0 references

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000216122

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000216122

ENSP00000371441

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000371441

ENSP00000393977

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000393977

ENSP00000408705

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000408705

ENSP00000412847

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000412847

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

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Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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