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GA binding protein transcription factor subunit alpha (Q21107537)

From Wikidata

mammalian protein found in Homo sapiens

nuclear respiratory factor 2 subunit alpha
nuclear respiratory factor 2 alpha subunit
GABPA
GA binding protein transcription factor alpha subunit 60kDa
GA-binding protein alpha chain
human nuclear respiratory factor-2 subunit alpha
transcription factor E4TF1-60
GABP subunit alpha

Language	Label	Description	Also known as
default for all languages	No label defined
English	GA binding protein transcription factor subunit alpha	mammalian protein found in Homo sapiens	nuclear respiratory factor 2 subunit alpha nuclear respiratory factor 2 alpha subunit GABPA GA binding protein transcription factor alpha subunit 60kDa GA-binding protein alpha chain human nuclear respiratory factor-2 subunit alpha transcription factor E4TF1-60 GABP subunit alpha

Statements

1 reference

13 November 2019

UniProt protein ID

winged helix DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q06546

Ubiquitin-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q06546

Winged helix-like DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q06546

Transcription factor, GA-binding, alpha subunit

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q06546

Sterile alpha motif/pointed domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q06546

GA-binding protein alpha subunit, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

ETS transcription factor family

1 reference

based on heuristic

inferred from protein domain or family

Pointed domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

determination method or standard

3 references

8 April 2019

cDNA cloning of transcription factor E4TF1 subunits with Ets and notch motifs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

sequence-specific DNA binding

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

DNA-binding transcription factor activity

determination method or standard

3 references

8 April 2019

cDNA cloning of transcription factor E4TF1 subunits with Ets and notch motifs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

8 April 2019

Mapping of the human transcription factor GABPA (E4TF1-60) gene to chromosome 21

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

DNA-binding transcription activator activity, RNA polymerase II-specific

determination method or standard

3 references

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

8 April 2019

Ets transcription factors ER81 and Elk1 regulate the transcription of the human presenilin 1 gene promoter

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

8 April 2019

Identification of Rhit as a novel transcriptional repressor of human Mpv17-like protein with a mitigating effect on mitochondrial dysfunction, and its transcriptional regulation by FOXD3 and GABP

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

transcription coactivator activity

determination method or standard

1 reference

8 April 2019

cDNA cloning of transcription factor E4TF1 subunits with Ets and notch motifs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

DNA-binding transcription activator activity, RNA polymerase II-specific

determination method or standard

1 reference

10 September 2018

Ets transcription factors ER81 and Elk1 regulate the transcription of the human presenilin 1 gene promoter

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06546&geneProductId=UniProtKB:Q06546

determination method or standard

chromatin binding

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

RNA polymerase II cis-regulatory region sequence-specific DNA binding

determination method or standard

2 references

8 April 2019

Ets transcription factors ER81 and Elk1 regulate the transcription of the human presenilin 1 gene promoter

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

8 April 2019

Identification of Rhit as a novel transcriptional repressor of human Mpv17-like protein with a mitigating effect on mitochondrial dysfunction, and its transcriptional regulation by FOXD3 and GABP

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

protein binding

determination method or standard

1 reference

8 April 2019

The novel coactivator C1 (HCF) coordinates multiprotein enhancer formation and mediates transcription activation by GABP

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

protein heterodimerization activity

determination method or standard

1 reference

8 April 2019

Transcriptional up-regulation of the delayed early gene HRS/SRp40 during liver regeneration. Interactions among YY1, GA-binding proteins, and mitogenic signals

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

DNA-binding transcription factor activity, RNA polymerase II-specific

determination method or standard

3 references

27 March 2018

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06546&geneProductId=UniProtKB:Q06546

determination method or standard

27 March 2018

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06546&geneProductId=UniProtKB:Q06546

determination method or standard

27 March 2018

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06546&geneProductId=UniProtKB:Q06546

determination method or standard

DNA-binding transcription factor activity, RNA polymerase II-specific

determination method or standard

4 references

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

determination method or standard

5 references

27 March 2018

Functional domains of transcription factor hGABP beta1/E4TF1-53 required for nuclear localization and transcription activation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06546&geneProductId=UniProtKB:Q06546

determination method or standard

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06546&geneProductId=UniProtKB:Q06546

determination method or standard

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06546&geneProductId=UniProtKB:Q06546

determination method or standard

27 March 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06546&geneProductId=UniProtKB:Q06546

determination method or standard

27 March 2018

Transcriptional up-regulation of the delayed early gene HRS/SRp40 during liver regeneration. Interactions among YY1, GA-binding proteins, and mitogenic signals

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06546&geneProductId=UniProtKB:Q06546

determination method or standard

determination method or standard

6 references

8 April 2019

Functional domains of transcription factor hGABP beta1/E4TF1-53 required for nuclear localization and transcription activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

8 April 2019

Transcriptional up-regulation of the delayed early gene HRS/SRp40 during liver regeneration. Interactions among YY1, GA-binding proteins, and mitogenic signals

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

biological process

cell differentiation

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

regulation of transcription, DNA-templated

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

regulation of transcription by RNA polymerase II

determination method or standard

1 reference

27 March 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06546&geneProductId=UniProtKB:Q06546

determination method or standard

mitochondrion organization

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

in utero embryonic development

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

negative regulation of transcription by RNA polymerase II

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

negative regulation of megakaryocyte differentiation

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

transcription, DNA-templated

determination method or standard

1 reference

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06546&geneProductId=UniProtKB:Q06546

determination method or standard

positive regulation of transcription by RNA polymerase II

determination method or standard

4 references

8 April 2019

METTL23, a transcriptional partner of GABPA, is essential for human cognition

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

8 April 2019

Ets transcription factors ER81 and Elk1 regulate the transcription of the human presenilin 1 gene promoter

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

8 April 2019

Transcriptional up-regulation of the delayed early gene HRS/SRp40 during liver regeneration. Interactions among YY1, GA-binding proteins, and mitogenic signals

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

8 April 2019

Identification of Rhit as a novel transcriptional repressor of human Mpv17-like protein with a mitigating effect on mitochondrial dysfunction, and its transcriptional regulation by FOXD3 and GABP

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

transcription by RNA polymerase II

determination method or standard

1 reference

8 April 2019

cDNA cloning of transcription factor E4TF1 subunits with Ets and notch motifs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

positive regulation of gene expression

determination method or standard

1 reference

8 April 2019

Cytosolic sulfotransferase 1A3 is induced by dopamine and protects neuronal cells from dopamine toxicity: role of D1 receptor-N-methyl-D-aspartate receptor coupling

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

cellular response to dopamine

determination method or standard

1 reference

8 April 2019

Cytosolic sulfotransferase 1A3 is induced by dopamine and protects neuronal cells from dopamine toxicity: role of D1 receptor-N-methyl-D-aspartate receptor coupling

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

blastocyst formation

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06546

determination method or standard

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q06546

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q06546

GA-binding protein alpha subunit, N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q06546

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000346886

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000346886

ENSP00000382948

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000382948

PDB structure ID

1 reference

9 November 2015

http://www.uniprot.org/uniprot/Q00422.txt?version=148

1 reference

9 November 2015

http://www.uniprot.org/uniprot/Q00422.txt?version=148

1 reference

9 November 2015

http://www.uniprot.org/uniprot/Q00422.txt?version=148

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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