Nuclear receptor binding SET domain protein 3 (Q21106554)

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mammalian protein found in Homo sapiens

protein whistle
histone-lysine N-methyltransferase NSD3
Wolf-Hirschhorn syndrome candidate 1-like 1
Wolf-Hirschhorn syndrome candidate 1-like protein 1
WHSC1-like protein 1
NSD3
WHSC1-like 1 isoform 9 with methyltransferase activity to lysine
nuclear SET domain-containing protein 3

Language	Label	Description	Also known as
English	Nuclear receptor binding SET domain protein 3	mammalian protein found in Homo sapiens	protein whistle histone-lysine N-methyltransferase NSD3 Wolf-Hirschhorn syndrome candidate 1-like 1 Wolf-Hirschhorn syndrome candidate 1-like protein 1 WHSC1-like protein 1 NSD3 WHSC1-like 1 isoform 9 with methyltransferase activity to lysine nuclear SET domain-containing protein 3

Statements

1 reference

13 November 2019

UniProt protein ID

Zinc finger, FYVE/PHD-type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9BZ95

Zinc finger, RING/FYVE/PHD-type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9BZ95

Zinc finger, PHD-finger, protein family

1 reference

based on heuristic

inferred from protein domain or family

Zinc finger, PHD-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

Post-SET domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

SET domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

PWWP domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

AWS domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Zinc finger, PHD-type, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

methyltransferase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZ95

determination method

transferase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZ95

determination method

protein binding

determination method

5 references

8 April 2019

The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZ95

determination method

8 April 2019

Structural Mechanism of the Oxygenase JMJD6 Recognition by the Extraterminal (ET) Domain of BRD4.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZ95

determination method

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZ95

determination method

8 April 2019

Systematic identification of molecular links between core and candidate genes in breast cancer

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZ95

determination method

8 April 2019

A Y2H-seq approach defines the human protein methyltransferase interactome

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZ95

determination method

metal ion binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZ95

determination method

histone-lysine N-methyltransferase activity

determination method

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BZ95&geneProductId=UniProtKB:Q9BZ95

determination method

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BZ95&geneProductId=UniProtKB:Q9BZ95

determination method

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BZ95&geneProductId=UniProtKB:Q9BZ95

determination method

1 January 2018

Characterization of a novel WHSC1-associated SET domain protein with H3K4 and H3K27 methyltransferase activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BZ95&geneProductId=UniProtKB:Q9BZ95

determination method

transcription coactivator activity

determination method

1 reference

8 April 2019

The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZ95

determination method

histone methyltransferase activity (H3-K36 specific)

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZ95

determination method

histone-lysine N-methyltransferase activity

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZ95

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZ95

determination method

8 April 2019

Characterization of a novel WHSC1-associated SET domain protein with H3K4 and H3K27 methyltransferase activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZ95

determination method

determination method

3 references

27 February 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BZ95&geneProductId=UniProtKB:Q9BZ95

determination method

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BZ95&geneProductId=UniProtKB:Q9BZ95

determination method

27 February 2018

Characterization of a novel WHSC1-associated SET domain protein with H3K4 and H3K27 methyltransferase activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BZ95&geneProductId=UniProtKB:Q9BZ95

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZ95

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZ95

determination method

determination method

4 references

16 July 2018

The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BZ95&geneProductId=UniProtKB:Q9BZ95

determination method

16 July 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BZ95&geneProductId=UniProtKB:Q9BZ95

determination method

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BZ95&geneProductId=UniProtKB:Q9BZ95

determination method

16 July 2018

Characterization of a novel WHSC1-associated SET domain protein with H3K4 and H3K27 methyltransferase activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BZ95&geneProductId=UniProtKB:Q9BZ95

determination method

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZ95

determination method

determination method

5 references

8 April 2019

The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZ95

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZ95

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZ95

determination method

8 April 2019

Characterization of a novel WHSC1-associated SET domain protein with H3K4 and H3K27 methyltransferase activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZ95

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZ95

determination method

biological process

histone methylation

determination method

1 reference

8 April 2019

Characterization of a novel WHSC1-associated SET domain protein with H3K4 and H3K27 methyltransferase activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZ95

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZ95

determination method

regulation of transcription, DNA-templated

determination method

1 reference

16 July 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BZ95&geneProductId=UniProtKB:Q9BZ95

determination method

transcription, DNA-templated

determination method

1 reference

16 July 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BZ95&geneProductId=UniProtKB:Q9BZ95

determination method

histone lysine methylation

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZ95

determination method

chromatin organization

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZ95

determination method

positive regulation of transcription, DNA-templated

determination method

1 reference

8 April 2019

The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZ95

determination method

positive regulation of histone H3-K36 trimethylation

determination method

1 reference

8 April 2019

The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZ95

determination method

regulation of transcription, DNA-templated

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZ95

determination method

histone H3-K36 methylation

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZ95

determination method

Zinc finger, PHD-type, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9BZ95

Zinc finger, PHD-finger

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9BZ95

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9BZ95

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9BZ95

Post-SET domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9BZ95

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9BZ95

Zinc finger, PHD-type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9BZ95

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000313410

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000313410

ENSP00000313983

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000313983

ENSP00000393284

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000393284

ENSP00000434730

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000434730

ENSP00000431598

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000431598

ENSP00000432544

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000432544

ENSP00000435073

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000435073

ENSP00000435422

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000435422

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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