Hepsin (Q21106301)

SRCR-like domain superfamily

1 reference

Hepsin

1 reference

Serine proteases, trypsin domain, protein family

1 reference

Serine proteases, trypsin family, histidine active site, protein family

1 reference

Hepsin, SRCR domain, protein family

1 reference

SRCR-like domain, protein family

1 reference

Serine proteases, trypsin family, serine active site, protein family

1 reference

serine-type exopeptidase activity

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

calcium-activated potassium channel activity

IEA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

8 April 2019

Pro-urokinase-type plasminogen activator is a substrate for hepsin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

8 April 2019

Pegylated kunitz domain inhibitor suppresses hepsin-mediated invasive tumor growth and metastasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

serine-type peptidase activity

4 references

8 April 2019

Hepsin, a cell membrane-associated protease. Characterization, tissue distribution, and gene localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

8 April 2019

Hepsin activates prostasin and cleaves the extracellular domain of the epidermal growth factor receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

serine-type endopeptidase activity

IEA

3 references

1 reference

8 April 2019

Human hepatitis B virus X protein promotes cell proliferation and inhibits cell apoptosis through interacting with a serine protease Hepsin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

endoplasmic reticulum membrane

1 reference

8 April 2019

An integrated genetic and functional analysis of the role of type II transmembrane serine proteases (TMPRSSs) in hearing loss

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

2 references

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

integral component of plasma membrane

1 reference

8 April 2019

Hepsin, a cell membrane-associated protease. Characterization, tissue distribution, and gene localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

apical plasma membrane

1 reference

8 April 2019

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

IEA

extracellular exosome

3 references

extracellular exosome

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

positive regulation of hepatocyte proliferation

HDA

biological process

1 reference

8 April 2019

Human hepatitis B virus X protein promotes cell proliferation and inhibits cell apoptosis through interacting with a serine protease Hepsin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

positive regulation of plasminogen activation

1 reference

8 April 2019

Pro-urokinase-type plasminogen activator is a substrate for hepsin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

response to thyroid hormone

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

negative regulation of apoptotic process

1 reference

8 April 2019

Human hepatitis B virus X protein promotes cell proliferation and inhibits cell apoptosis through interacting with a serine protease Hepsin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

8 April 2019

Pro-urokinase-type plasminogen activator is a substrate for hepsin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

8 April 2019

Pegylated kunitz domain inhibitor suppresses hepsin-mediated invasive tumor growth and metastasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

8 April 2019

Hepsin activates prostasin and cleaves the extracellular domain of the epidermal growth factor receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

8 April 2019

TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

detection of mechanical stimulus involved in sensory perception of sound

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

positive regulation of thyroid hormone generation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

positive regulation of cell growth

1 reference

8 April 2019

Hepsin, a putative cell-surface serine protease, is required for mammalian cell growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

positive regulation of gene expression

IMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

cochlea morphogenesis

1 reference

8 April 2019

potassium ion transmembrane transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

Hepsin, a putative cell-surface serine protease, is required for mammalian cell growth

regulation of cell shape

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05981&geneProductId=UniProtKB:P05981

negative regulation of epithelial cell proliferation

IMP

1 reference

8 April 2019

Pegylated kunitz domain inhibitor suppresses hepsin-mediated invasive tumor growth and metastasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

basement membrane disassembly

1 reference

8 April 2019

Pro-urokinase-type plasminogen activator is a substrate for hepsin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

negative regulation of epithelial to mesenchymal transition

1 reference

26 September 2017

Pegylated kunitz domain inhibitor suppresses hepsin-mediated invasive tumor growth and metastasis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05981&geneProductId=UniProtKB:P05981

hepatocyte growth factor receptor signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981

negative regulation of epithelial to mesenchymal transition

TAS

serine proteases, trypsin domain

1 reference

SRCR-like domain

1 reference

serine proteases, trypsin family, histidine active site

1 reference

Serine proteases, trypsin family, serine active site

1 reference

hepsin, SRCR domain

1 reference

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 June 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016