Oxidative stress responsive kinase 1 (Q21105493)

Protein kinase-like domain superfamily

1 reference

Serine/threonine-protein kinase OSR1/WNK, CCT domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase, ATP binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

magnesium ion binding

1 reference

8 April 2019

Characterization of OSR1, a member of the mammalian Ste20p/germinal center kinase subfamily

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

protein kinase activity

1 reference

8 April 2019

6 references

8 April 2019

The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transporters

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

8 April 2019

Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

8 April 2019

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

8 April 2019

Structural insights into the recognition of substrates and activators by the OSR1 kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

8 April 2019

MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

8 April 2019

WNK1 and OSR1 regulate the Na+, K+, 2Cl- cotransporter in HeLa cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

8 April 2019

Characterization of OSR1, a member of the mammalian Ste20p/germinal center kinase subfamily

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

protein serine/threonine kinase activity

6 references

24 October 2017

Isolation and characterization of a novel serine threonine kinase gene on chromosome 3p22-21.3

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95747&geneProductId=UniProtKB:O95747

24 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95747&geneProductId=UniProtKB:O95747

24 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95747&geneProductId=UniProtKB:O95747

24 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95747&geneProductId=UniProtKB:O95747

24 October 2017

Characterization of OSR1, a member of the mammalian Ste20p/germinal center kinase subfamily

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95747&geneProductId=UniProtKB:O95747

24 October 2017

The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transporters

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95747&geneProductId=UniProtKB:O95747

identical protein binding

1 reference

8 April 2019

WNK1 and OSR1 regulate the Na+, K+, 2Cl- cotransporter in HeLa cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

protein serine/threonine kinase activity

IPI

8 references

8 April 2019

Isolation and characterization of a novel serine threonine kinase gene on chromosome 3p22-21.3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

8 April 2019

Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

8 April 2019

Characterization of OSR1, a member of the mammalian Ste20p/germinal center kinase subfamily

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

8 April 2019

The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transporters

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1

protein kinase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

Large-scale proteomics and phosphoproteomics of urinary exosomes

IPI

cell component

extracellular exosome

1 reference

24 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95747&geneProductId=UniProtKB:O95747

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

Large-scale proteomics and phosphoproteomics of urinary exosomes

extracellular exosome

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

negative regulation of potassium ion transmembrane transport

HDA

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

cellular hypotonic response

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

negative regulation of potassium ion transmembrane transporter activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

Isolation and characterization of a novel serine threonine kinase gene on chromosome 3p22-21.3

protein phosphorylation

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

8 April 2019

Characterization of OSR1, a member of the mammalian Ste20p/germinal center kinase subfamily

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

intracellular signal transduction

regulation of mitotic cell cycle

3 references

1 reference

24 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95747&geneProductId=UniProtKB:O95747

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

stress-activated protein kinase signaling cascade

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

activation of protein kinase activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

regulation of apoptotic process

1 reference

24 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95747&geneProductId=UniProtKB:O95747

osmosensory signaling pathway

1 reference

8 April 2019

Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

peptidyl-threonine phosphorylation

IMP

3 references

8 April 2019

Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

8 April 2019

The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transporters

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

chemokine (C-X-C motif) ligand 12 signaling pathway

1 reference

8 April 2019

WNK1 kinase balances T cell adhesion versus migration in vivo

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

protein autophosphorylation

IMP

1 reference

8 April 2019

Identification of PLSCR1 as a protein that interacts with RELT family members

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95747

protein kinase, ATP binding site

has part(s)

1 reference

protein kinase domain

1 reference

Serine/threonine-protein kinase OSR1/WNK, CCT domain

1 reference