Interferon alpha and beta receptor subunit 1 (Q21101335)

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mammalian protein found in Homo sapiens

IFN-alpha/beta receptor 1
CRF2-1
alpha-type antiviral protein
beta-type antiviral protein
interferon-alpha/beta receptor alpha chain
cytokine receptor class-II member 1
interferon-beta receptor 1
interferon receptor 1
interferon alpha/beta receptor 1
interferon (alpha, beta and omega) receptor 1
type I interferon receptor 1
IFNAR1
cytokine receptor family 2 member 1
IFN-R-1

Language	Label	Description	Also known as
English	Interferon alpha and beta receptor subunit 1	mammalian protein found in Homo sapiens	IFN-alpha/beta receptor 1 CRF2-1 alpha-type antiviral protein beta-type antiviral protein interferon-alpha/beta receptor alpha chain cytokine receptor class-II member 1 interferon-beta receptor 1 interferon receptor 1 interferon alpha/beta receptor 1 interferon (alpha, beta and omega) receptor 1 type I interferon receptor 1 IFNAR1 cytokine receptor family 2 member 1 IFN-R-1

Statements

1 reference

16 January 2019

UniProt protein ID

Fibronectin type III superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P17181

Immunoglobulin-like fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P17181

Interferon alpha/beta receptor 1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P17181

auxiliary protein involved in transmembrane transport

1 reference

Transporter Classification Database ID

2 October 2019

based on heuristic

hierarchical database ID heuristic

Fibronectin type III, protein family

1 reference

based on heuristic

inferred from protein domain or family

Interferon/interleukin receptor domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

16 January 2019

UniProt protein ID

1 reference

16 January 2019

UniProt protein ID

molecular function

interferon receptor activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17181

determination method

protein binding

determination method

6 references

8 April 2019

Cloning and expression of a long form of the beta subunit of the interferon alpha beta receptor that is required for signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17181

determination method

8 April 2019

Affinity of Stat2 for the subunits of the interferon alpha receptor

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17181

determination method

8 April 2019

SCFHOS ubiquitin ligase mediates the ligand-induced down-regulation of the interferon- receptor

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17181

determination method

8 April 2019

Identification of amino acid residues critical for the Src-homology 2 domain-dependent docking of Stat2 to the interferon alpha receptor

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17181

determination method

8 April 2019

Functional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signaling

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17181

determination method

8 April 2019

Phosphorylated interferon-alpha receptor 1 subunit (IFNaR1) acts as a docking site for the latent form of the 113 kDa STAT2 protein

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17181

determination method

interleukin-10 receptor activity

determination method

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17181&geneProductId=UniProtKB:P17181

determination method

type I interferon receptor activity

determination method

1 reference

8 April 2019

Cloning and expression of a long form of the beta subunit of the interferon alpha beta receptor that is required for signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17181

determination method

type I interferon binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17181

determination method

cytokine receptor activity

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17181

determination method

integral component of membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17181

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17181

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17181

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17181

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17181

determination method

plasma membrane

determination method

biological process

receptor signaling pathway via JAK-STAT

determination method

1 reference

8 April 2019

Cloning and expression of a long form of the beta subunit of the interferon alpha beta receptor that is required for signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17181

determination method

response to virus

determination method

1 reference

8 April 2019

Genetic transfer of a functional human interferon alpha receptor into mouse cells: cloning and expression of its cDNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17181

determination method

cytokine-mediated signaling pathway

determination method

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17181&geneProductId=UniProtKB:P17181

determination method

response to lipopolysaccharide

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17181

determination method

cellular response to interferon-alpha

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17181

determination method

physically interacts with

interferon alfacon-1

object has role

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1201557

peginterferon beta-1a

object has role

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL2108677

interferon beta-1b

object has role

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1201563

interferon beta-1a

object has role

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1201562

fibronectin type III

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P17181

Interferon/interleukin receptor domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P17181

Identifiers

RefSeq protein ID

1 reference

16 November 2018

1 reference

16 November 2018

1 reference

16 November 2018

UniProt protein ID

1 reference

16 January 2019

UniProt protein ID

Ensembl protein ID

ENSP00000270139

1 reference

ensembl Release 95

Ensembl protein ID

ENSP00000270139

ENSP00000400161

1 reference

ensembl Release 95

Ensembl protein ID

ENSP00000400161

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Transporter Classification Database ID

2 references

Transporter Classification database

13 March 2020

Transporter Classification database

29 April 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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