Cyclin E1 (Q21100448)

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mammalian protein found in Homo sapiens
  • CCNE1
  • G1/S-specific cyclin-E1
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Language Label Description Also known as
English
Cyclin E1
mammalian protein found in Homo sapiens
  • CCNE1
  • G1/S-specific cyclin-E1

Statements

molecular function
protein binding
determination method
IPI
23 references
retrieved
9 May 2019
stated in
NIRF constitutes a nodal point in the cell cycle network and is a candidate tumor suppressor
GOA
curator
UniProt
UniProt protein ID
P24864
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864
determination method
IPI
retrieved
9 May 2019
stated in
Inhibitor of cyclin-dependent kinase (CDK) interacting with cyclin A1 (INCA1) regulates proliferation and is repressed by oncogenic signaling
GOA
curator
UniProt
UniProt protein ID
P24864
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864
determination method
IPI
retrieved
9 May 2019
stated in
Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases
GOA
curator
UniProt
UniProt protein ID
P24864
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864
determination method
IPI
retrieved
9 May 2019
stated in
Cyclin E associates with BAF155 and BRG1, components of the mammalian SWI-SNF complex, and alters the ability of BRG1 to induce growth arrest
GOA
curator
UniProt
UniProt protein ID
P24864
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864
determination method
IPI
retrieved
9 May 2019
stated in
NIRF constitutes a nodal point in the cell cycle network and is a candidate tumor suppressor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864
determination method
IPI
retrieved
9 May 2019
stated in
Foxp3 protein stability is regulated by cyclin-dependent kinase 2
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864
determination method
IPI
retrieved
9 May 2019
stated in
The protein interaction landscape of the human CMGC kinase group
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864
determination method
IPI
retrieved
9 May 2019
stated in
Toward an understanding of the protein interaction network of the human liver
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864
determination method
IPI
retrieved
9 May 2019
stated in
p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864
determination method
IPI
retrieved
9 May 2019
stated in
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864
determination method
IPI
retrieved
9 May 2019
stated in
Regulation of the transcription factor FOXM1c by Cyclin E/CDK2
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864
determination method
IPI
retrieved
9 May 2019
stated in
G1/S Cyclins interact with regulatory subunit of PKA via A-kinase anchoring protein, AKAP95
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864
determination method
IPI
retrieved
9 May 2019
stated in
Polycomb protein SCML2 regulates the cell cycle by binding and modulating CDK/CYCLIN/p21 complexes.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864
determination method
IPI
retrieved
9 May 2019
stated in
HTLV-I p30 inhibits multiple S phase entry checkpoints, decreases cyclin E-CDK2 interactions and delays cell cycle progression
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864
determination method
IPI
retrieved
9 May 2019
stated in
Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864
determination method
IPI
retrieved
9 May 2019
stated in
Cyclin-binding motifs are essential for the function of p21CIP1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864
determination method
IPI
retrieved
9 May 2019
stated in
Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864
determination method
IPI
retrieved
9 May 2019
stated in
Specificity of cyclin E-Cdk2, TFIIB, and E1A interactions with a common domain of the p300 coactivator
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864
determination method
IPI
retrieved
9 May 2019
stated in
Cyclin E2, a novel human G1 cyclin and activating partner of CDK2 and CDK3, is induced by viral oncoproteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864
determination method
IPI
retrieved
9 May 2019
stated in
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864
determination method
IPI
retrieved
9 May 2019
stated in
RSK1 drives p27Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864
determination method
IPI
retrieved
9 May 2019
stated in
Increased p21 expression and complex formation with cyclin E/CDK2 in retinoid-induced pre-B lymphoma cell apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864
determination method
IPI
retrieved
9 May 2019
stated in
Cdk-inhibitory activity and stability of p27Kip1 are directly regulated by oncogenic tyrosine kinases
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864
determination method
IPI
cell component
biological process

Identifiers

 
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