Tight junction protein 1 (Q21096429)

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mammalian protein found in Homo sapiens
  • zonula occludens 1 protein
  • tight junction protein ZO-1
  • TJP1
  • Zonula occludens protein 1
  • zona occludens 1
  • Zona occludens protein 1
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Language Label Description Also known as
English
Tight junction protein 1
mammalian protein found in Homo sapiens
  • zonula occludens 1 protein
  • tight junction protein ZO-1
  • TJP1
  • Zonula occludens protein 1
  • zona occludens 1
  • Zona occludens protein 1

Statements

molecular function
protein binding
determination method
IPI
17 references
retrieved
8 April 2019
stated in
Crystal structure of the tricellulin C-terminal coiled-coil domain reveals a unique mode of dimerization.
GOA
curator
UniProt
UniProt protein ID
Q07157
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07157
determination method
IPI
retrieved
8 April 2019
stated in
Cdc42 GEF Tuba regulates the junctional configuration of simple epithelial cells.
GOA
curator
UniProt
UniProt protein ID
Q07157
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07157
determination method
IPI
retrieved
8 April 2019
stated in
Characterization of the ubinuclein protein as a new member of the nuclear and adhesion complex components (NACos)
GOA
curator
UniProt
UniProt protein ID
Q07157
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07157
determination method
IPI
retrieved
8 April 2019
stated in
Expression and function of connexin 43 protein in mouse and human retinal pigment epithelial cells as hemichannels and gap junction proteins.
GOA
curator
UniProt
UniProt protein ID
Q07157
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07157
determination method
IPI
retrieved
8 April 2019
stated in
JAM-A associates with ZO-2, afadin, and PDZ-GEF1 to activate Rap2c and regulate epithelial barrier function
GOA
curator
UniProt
UniProt protein ID
Q07157
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07157
determination method
IPI
retrieved
8 April 2019
stated in
Human and Xenopus cingulin share a modular organization of the coiled-coil rod domain: predictions for intra- and intermolecular assembly
GOA
curator
UniProt
UniProt protein ID
Q07157
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07157
determination method
IPI
retrieved
8 April 2019
stated in
The coxsackievirus and adenovirus receptor is a transmembrane component of the tight junction
GOA
curator
UniProt
UniProt protein ID
Q07157
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07157
determination method
IPI
retrieved
8 April 2019
stated in
Motor protein Myo1c is a podocyte protein that facilitates the transport of slit diaphragm protein Neph1 to the podocyte membrane
GOA
curator
UniProt
UniProt protein ID
Q07157
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07157
determination method
IPI
retrieved
8 April 2019
stated in
Reduced expression of vacuole membrane protein 1 affects the invasion capacity of tumor cells
GOA
curator
UniProt
UniProt protein ID
Q07157
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07157
determination method
IPI
retrieved
8 April 2019
stated in
Tight junction-associated MARVEL proteins marveld3, tricellulin, and occludin have distinct but overlapping functions
GOA
curator
UniProt
UniProt protein ID
Q07157
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07157
determination method
IPI
retrieved
8 April 2019
stated in
Density-enhanced phosphatase 1 regulates phosphorylation of tight junction proteins and enhances barrier function of epithelial cells
GOA
curator
UniProt
UniProt protein ID
Q07157
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07157
determination method
IPI
retrieved
8 April 2019
stated in
Molecular cloning, functional expression, and tissue distribution of a novel human gap junction-forming protein, connexin-31.9. Interaction with zona occludens protein-1
GOA
curator
UniProt
UniProt protein ID
Q07157
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07157
determination method
IPI
retrieved
8 April 2019
stated in
Interaction of zonula occludens-1 (ZO-1) with alpha-actinin-4: application of functional proteomics for identification of PDZ domain-associated proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07157
determination method
IPI
retrieved
8 April 2019
stated in
Solution structure analysis of cytoplasmic domain of podocyte protein Neph1 using small/wide angle x-ray scattering (SWAXS)
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07157
determination method
IPI
retrieved
8 April 2019
stated in
The gap junction protein connexin43 interacts with the second PDZ domain of the zona occludens-1 protein
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07157
determination method
IPI
retrieved
8 April 2019
stated in
TAZ interacts with zonula occludens-1 and -2 proteins in a PDZ-1 dependent manner
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07157
determination method
IPI
retrieved
8 April 2019
stated in
Molecular cloning, functional expression, and tissue distribution of a novel human gap junction-forming protein, connexin-31.9. Interaction with zona occludens protein-1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07157
determination method
IPI
cell component
bicellular tight junction
determination method
IDA
IEA
TAS
7 references
retrieved
8 April 2019
stated in
The 220-kD protein colocalizing with cadherins in non-epithelial cells is identical to ZO-1, a tight junction-associated protein in epithelial cells: cDNA cloning and immunoelectron microscopy
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07157
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q07157
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07157
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07157
determination method
IEA
retrieved
8 April 2019
stated in
Characterization of the ubinuclein protein as a new member of the nuclear and adhesion complex components (NACos)
GOA
curator
UniProt
UniProt protein ID
Q07157
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07157
determination method
IDA
retrieved
8 April 2019
stated in
The coxsackievirus and adenovirus receptor is a transmembrane component of the tight junction
GOA
curator
UniProt
UniProt protein ID
Q07157
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07157
determination method
IDA
retrieved
8 April 2019
stated in
Lulu2 regulates the circumferential actomyosin tensile system in epithelial cells through p114RhoGEF
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07157
determination method
IDA
retrieved
8 April 2019
stated in
Lateral membrane biogenesis in human bronchial epithelial cells requires 190-kDa ankyrin-G
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07157
determination method
IDA

Identifiers

RefSeq protein ID
PDB structure ID
 
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