tobramycin (Q1758380)

Tobramycin (Saesneg)

23 Medi 2015

tobramycin metabolic process ^Saesneg

participant ^Saesneg

1 ffynhonnell

Gene Ontology release 2019-11-16 ^Saesneg

tobramycin catabolic process ^Saesneg

reactant ^Saesneg

1 ffynhonnell

Gene Ontology release 2019-11-16 ^Saesneg

tobramycin biosynthetic process ^Saesneg

product ^Saesneg

1 ffynhonnell

Gene Ontology release 2019-11-16 ^Saesneg

adeiledd gemegol

Tobramycin.svg
490 × 190; 4 KB

0 ffynonellau

màs

467.259 uned Dalton

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

tobramycin (Saesneg)

17 Tachwedd 2016

C₁₈H₃₇N₅O₉

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

tobramycin (Saesneg)

17 Tachwedd 2016

C1C(C(C(C(C1N)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(CC(C(O3)CN)O)N)N

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

tobramycin (Saesneg)

17 Tachwedd 2016

isomeric SMILES ^Saesneg

C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)N)O)O)O[C@@H]3[C@@H](C[C@@H]([C@H](O3)CN)O)N)N

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

tobramycin (Saesneg)

17 Tachwedd 2016

Tobi Podhaler ^Saesneg

1 ffynhonnell

European Medicines Agency product number ^Saesneg

EMEA/H/C/002155

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/002155/human_med_001401.jsp

22 Mawrth 2017

Vantobra ^Saesneg

1 ffynhonnell

European Medicines Agency product number ^Saesneg

EMEA/H/C/002633

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/002633/human_med_001773.jsp

22 Mawrth 2017

Tobi ^Saesneg

1 ffynhonnell

RxNorm ^Saesneg

RxNorm ID ^Saesneg

220329

14 Chwefror 2018

Tobrex ^Saesneg

1 ffynhonnell

RxNorm ^Saesneg

RxNorm ID ^Saesneg

220333

14 Chwefror 2018

Bethkis ^Saesneg

1 ffynhonnell

RxNorm ^Saesneg

RxNorm ID ^Saesneg

1314764

14 Chwefror 2018

Kitabis ^Saesneg

1 ffynhonnell

RxNorm ^Saesneg

RxNorm ID ^Saesneg

1596026

14 Chwefror 2018

World Health Organisation international non-proprietary name ^Saesneg

tobramycin (Saesneg)

2 ffynonellau

ChEMBL ^Saesneg

ChEMBL ID ^Saesneg

Tobramycin (Saesneg)

cyhoeddwyd fel rhan o'r canlynol

9 Hydref 2015

Recommended INN: List 15 ^Saesneg

dyddiad cyhoeddi

1975

found in taxon ^Saesneg

Streptoalloteichus hindustanus ^Saesneg

1 ffynhonnell

Biosynthesis of 2-deoxystreptamine-containing antibiotics in Streptoalloteichus hindustanus JCM 3268: characterization of 2-deoxy-scyllo-inosose synthase. ^Saesneg

Streptomyces cremeus ^Saesneg

9 ffynonellau

Isolation and characterization of the tobramycin biosynthetic gene cluster from Streptomyces tenebrarius ^Saesneg

An approach for cloning biosynthetic genes of 2-deoxystreptamine-containing aminocyclitol antibiotics: isolation of a biosynthetic gene cluster of tobramycin from Streptomyces tenebrarius ^Saesneg

Cloning and analysis of a gene (SMS13) encoding sannamycin B-glycyltransferase from Streptomyces sannanensis and its distribution among actinomycetes. ^Saesneg

Characterization of L-glutamine:2-deoxy-scyllo-inosose aminotransferase (tbmB) from Streptomyces tenebrarius ^Saesneg

Analysis of a ribosomal RNA methylase gene from Streptomyces tenebrarius which confers resistance to gentamicin. ^Saesneg

Construction of kanamycin B overproducing strain by genetic engineering of Streptomyces tenebrarius. ^Saesneg

Involvement of 16S ribosomal RNA in resistance of the aminoglycoside-producers Streptomyces tenjimariensis, Streptomyces tenebrarius and Micromonospora purpurea ^Saesneg

Identification and functional analysis of dTDP-glucose-4,6-dehydratase gene and its linked gene cluster in an aminoglycoside antibiotics producer of Streptomyces tenebrarius H6. ^Saesneg

Biosynthesis of 3'-deoxy-carbamoylkanamycin C in a Streptomyces tenebrarius mutant strain by tacB gene disruption ^Saesneg

Aspergillus fumigatus ^Saesneg

1 ffynhonnell

Helvolic Acid Derivatives with Antibacterial Activities against Streptococcus agalactiae from the Marine-Derived Fungus Aspergillus fumigatus HNMF0047 ^Saesneg

Serratia plymuthica ^Saesneg

1 ffynhonnell

Antibacterial 3,6-Disubstituted 4-Hydroxy-5,6-dihydro-2H-pyran-2-ones from Serratia plymuthica MF371-2. ^Saesneg

clefyd a drinir

haint yn yr uwch-pibellau anadlu

1 ffynhonnell

NDF-RT ^Saesneg

13 Rhagfyr 2016

1 ffynhonnell

NDF-RT ^Saesneg

haint bacteria sy'n adweithio'n negyddol i brofion Gram

13 Rhagfyr 2016

1 ffynhonnell

NDF-RT ^Saesneg

13 Rhagfyr 2016

Pseudomonas infection ^Saesneg

1 ffynhonnell

NDF-RT ^Saesneg

13 Rhagfyr 2016

2 ffynonellau

NDF-RT ^Saesneg

13 Rhagfyr 2016

https://www.ncbi.nlm.nih.gov/pubmed/789045

llid y cyfbilen

1 ffynhonnell

2 Hydref 2018

clefyd heintus bacterol

1 ffynhonnell

2 Hydref 2018

ffibrosis systig

1 ffynhonnell

2 Hydref 2018

niwmonia

1 ffynhonnell

2 Hydref 2018

bronciectasis

1 ffynhonnell

dyddiad neu amser cychwyn

2 Hydref 2018

ffibrosis systig

12 Chwefror 2014

cadarnhawyd gan

Food and Drug Administration ^Saesneg

1 ffynhonnell

Inxight: Drugs Database ^Saesneg

2 Tachwedd 2018

https://drugs.ncats.io/drug/VZ8RRZ51VK

significant drug interaction ^Saesneg

Ffoscarnet

side effect ^Saesneg

nephrotoxicity ^Saesneg

1 ffynhonnell

hypothetically ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

fancomycin

side effect ^Saesneg

nephrotoxicity ^Saesneg

1 ffynhonnell

hypothetically ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

ciclosporin

side effect ^Saesneg

nephrotoxicity ^Saesneg

1 ffynhonnell

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

carboplatin

side effect ^Saesneg

Ototoxicity ^Saesneg

1 ffynhonnell

hypothetically ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

bwmetanid

side effect ^Saesneg

Ototoxicity ^Saesneg

1 ffynhonnell

hypothetically ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

fancomycin

side effect ^Saesneg

Ototoxicity ^Saesneg

1 ffynhonnell

hypothetically ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

ffwrosemid

side effect ^Saesneg

Ototoxicity ^Saesneg

1 ffynhonnell

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

ffwrosemid

side effect ^Saesneg

nephrotoxicity ^Saesneg

1 ffynhonnell

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

carboplatin

side effect ^Saesneg

nephrotoxicity ^Saesneg

1 ffynhonnell

hypothetically ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

cisplatin

side effect ^Saesneg

nephrotoxicity ^Saesneg

1 ffynhonnell

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

cisplatin

side effect ^Saesneg

Ototoxicity ^Saesneg

1 ffynhonnell

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

bwmetanid

side effect ^Saesneg

nephrotoxicity ^Saesneg

1 ffynhonnell

hypothetically ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

rocuronium ^Saesneg

1 ffynhonnell

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

rocuronium ^Saesneg

side effect ^Saesneg

1 ffynhonnell

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

rocuronium ^Saesneg

side effect ^Saesneg

1 ffynhonnell

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

mivacurium ^Saesneg

1 ffynhonnell

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

mivacurium ^Saesneg

side effect ^Saesneg

1 ffynhonnell

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

mivacurium ^Saesneg

side effect ^Saesneg

1 ffynhonnell

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

atracurium ^Saesneg

1 ffynhonnell

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

atracurium ^Saesneg

side effect ^Saesneg

1 ffynhonnell

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

atracurium ^Saesneg

side effect ^Saesneg

1 ffynhonnell

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

cisatracurium ^Saesneg

1 ffynhonnell

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

cisatracurium ^Saesneg

side effect ^Saesneg

1 ffynhonnell

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

cisatracurium ^Saesneg

side effect ^Saesneg

1 ffynhonnell

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

ciclosporin

side effect ^Saesneg

methiant yr arennau

1 ffynhonnell

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

succinylcholine ^Saesneg

side effect ^Saesneg

1 ffynhonnell

hypothetically ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

succinylcholine ^Saesneg

side effect ^Saesneg

apnea ^Saesneg

1 ffynhonnell

hypothetically ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

cisplatin

side effect ^Saesneg

methiant yr arennau

1 ffynhonnell

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

legal status (medicine) ^Saesneg

boxed warning ^Saesneg

1 ffynhonnell

https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802

FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links. (Saesneg)

gwneuthurwr

Pfizer ^Saesneg

1 ffynhonnell

https://www.pfizer.com/products/product-list

protein synthesis inhibitor ^Saesneg

1 ffynhonnell

NDF-RT ^Saesneg

5 Mawrth 2018

1 ffynhonnell

15 Mawrth 2018

‎WHO Aware Classification ^Saesneg

watch ^Saesneg

1 ffynhonnell

InChI=1S/C18H37N5O9/c19-3-9-8(25)2-7(22)17(29-9)31-15-5(20)1-6(21)16(14(15)28)32-18-13(27)11(23)12(26)10(4-24)30-18/h5-18,24-28H,1-4,19-23H2/t5-,6+,7+,8-,9+,10+,11-,12+,13+,14-,15+,16-,17+,18+/m0/s1

2023 ‎AWaRe classification‎ ^Saesneg

categori Comin

Tobramycin

0 ffynonellau

Identifiers

InChI

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

tobramycin (Saesneg)

NLVFBUXFDBBNBW-PBSUHMDJSA-N

17 Tachwedd 2016

InChIKey ^Saesneg

2 ffynonellau

PubChem ^Saesneg

PubChem CID ^Saesneg

tobramycin (Saesneg)

17 Tachwedd 2016

ChEBI release 2020-09-01 ^Saesneg

Rhif Cofrestru CAS

32986-56-4

2 ffynonellau

UNII ^Saesneg

tobramycin (Saesneg)

NLVFBUXFDBBNBW-PBSUHMDJSA-N

17 Tachwedd 2016

InChIKey ^Saesneg

CAS Common Chemistry ^Saesneg

10 Ebrill 2021

https://commonchemistry.cas.org/detail?cas_rn=32986-56-4

ChemSpider ID ^Saesneg

33377

1 ffynhonnell

ChemSpider ^Saesneg

ChemSpider ID ^Saesneg

33377

Tobramycin (Saesneg)

17 Tachwedd 2016

PubChem CID ^Saesneg

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

tobramycin (Saesneg)

17 Tachwedd 2016

Reaxys registry number ^Saesneg

1357507

1 ffynhonnell

ChEBI ^Saesneg

ChEBI ID ^Saesneg

28864

tobramycin (Saesneg)

19 Hydref 2016

ChEBI ID ^Saesneg

28864

mapping relation type ^Saesneg

exact match ^Saesneg

1 ffynhonnell

ChEMBL ^Saesneg

ChEMBL ID ^Saesneg

TOBRAMYCIN (Saesneg)

17 Tachwedd 2016

ChEMBL ID ^Saesneg

1 ffynhonnell

ChEMBL ^Saesneg

ChEMBL ID ^Saesneg

TOBRAMYCIN (Saesneg)

seiliwyd ar dybiaethau esboniadol

17 Tachwedd 2016

SureChEMBL ID ^Saesneg

SCHEMBL2838

1 ffynhonnell

inferred from InChIKey ^Saesneg

UniChem compound ID ^Saesneg

404692

1 ffynhonnell

splash10-03di-0911100000-b28142c63090941c9e87

UniChem ^Saesneg

SPLASH ^Saesneg

0 ffynonellau

dynodwr HSDB

3259

1 ffynhonnell

Hazardous Substances Data Bank ^Saesneg

28 Hydref 2019

Tobramycin (Saesneg)

10 Mai 2021

DSSTox substance ID ^Saesneg

DTXSID8023680

1 ffynhonnell

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard ^Saesneg

DSSTOX compound identifier ^Saesneg

DTXCID903680

0 ffynonellau

NSC number ^Saesneg

180514

0 ffynonellau

757352

0 ffynonellau

EC number ^Saesneg

251-322-5

1 ffynhonnell

UNII ^Saesneg

tobramycin (Saesneg)

17 Tachwedd 2016

ECHA Substance Infocard ID ^Saesneg

100.046.642

1 ffynhonnell

ECHA Substance Infocard database ^Saesneg

ECHA Substance Infocard ID ^Saesneg

27 Rhagfyr 2018

Tobramycin (Saesneg)

CAS no.: 32986-56-4 (Saesneg)

Cod yr ATC

J01GB01

1 ffynhonnell

DrugBank ^Saesneg

Tobramycin (Saesneg)

23 Medi 2015

1 ffynhonnell

DrugBank ^Saesneg

Tobramycin (Saesneg)

dyddiad cyhoeddi

23 Medi 2015

World Health Organisation international non-proprietary name numeric ID ^Saesneg

2990

1 ffynhonnell

https://mednet-communities.net/inn/db/ViewINN.aspx?i=2990

dynodwr Llawlyfr Ffarmacoleg Ligand

10930

1 ffynhonnell

IUPHAR/BPS Guide to PHARMACOLOGY ^Saesneg

5 Chwefror 2021

Tobramycin

1 ffynhonnell

14 Mawrth 2018

D09.408.051.476.600.800

0 ffynonellau

RxNorm ID ^Saesneg

10627

1 ffynhonnell

UNII ^Saesneg

tobramycin (Saesneg)

17 Tachwedd 2016

1 ffynhonnell

DrugBank ^Saesneg

seiliwyd ar dybiaethau esboniadol

Tobramycin (Saesneg)

17 Tachwedd 2016

1 ffynhonnell

inferred from InChIKey ^Saesneg

UNII ^Saesneg

1 ffynhonnell

UNII ^Saesneg

tobramycin (Saesneg)

seiliwyd ar dybiaethau esboniadol

17 Tachwedd 2016

Natural Product Atlas ID ^Saesneg

NPA024722

1 ffynhonnell

inferred from InChIKey ^Saesneg

MedlinePlus drug identifier ^Saesneg

a681003

dull gweini

intravenous injection ^Saesneg

pigiad mewngyhyrol

0 ffynonellau

a682660

dull gweini

eye contact ^Saesneg

0 ffynonellau

1 ffynhonnell

UNII ^Saesneg

tobramycin (Saesneg)

17 Tachwedd 2016

Probes And Drugs ID ^Saesneg

PD001728

0 ffynonellau

DrugCentral ID ^Saesneg

1 ffynhonnell

UniChem ^Saesneg

1 ffynhonnell

ChEBI ^Saesneg

ChEBI ID ^Saesneg

28864

dynodwr Microsoft Academic

tobramycin (Saesneg)

19 Hydref 2016

0 ffynonellau

1 ffynhonnell

Freebase Data Dumps ^Saesneg

dyddiad cyhoeddi

28 Hydref 2013

2778974779

0 ffynonellau

OpenAlex ID ^Saesneg

1 ffynhonnell

OpenAlex ^Saesneg

26 Ionawr 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID ^Saesneg

1M4D

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

1M4D

1M4D (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

3SG8

3SG8 (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

5CFS

5CFS (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

4LFC

4LFC (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

4EBK

4EBK (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

4EVY

4EVY (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

1LC4

1LC4 (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

3VET

3VET (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

4XJE

4XJE (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

4JD6

4JD6 (Saesneg)

19 Hydref 2016

UMLS CUI ^Saesneg

C0040341

1 ffynhonnell

UNII ^Saesneg

tobramycin (Saesneg)

17 Tachwedd 2016

WikiProjectMed ID ^Saesneg

Tobramycin

0 ffynonellau

WordNet 3.1 Synset ID ^Saesneg

04450722-n

1 ffynhonnell