cobimetinib &#160; Béarla (Q15708292)

PubChem ^Béarla

PubChem CID ^Béarla

Cobimetinib (Béarla)

[3,4-Difluoro-2-(2-fluoro-4-iodoanilino)phenyl]{3-hydroxy-3-[(2R)-piperidin-2-yl]azetidin-1-yl}methanone ^Béarla

19 Deireadh Fómhair 2016

stereoisomer of ^Béarla

1 reference

bunaithe ar chur chuige heorastúil

inferred from InChI ^Béarla

foirmle cheimiceach

C₂₁H₂₁F₃IN₃O₂

1 reference

PubChem ^Béarla

PubChem CID ^Béarla

Cobimetinib (Béarla)

19 Samhain 2016

C1CCNC(C1)C2(CN(C2)C(=O)C3=C(C(=C(C=C3)F)F)NC4=C(C=C(C=C4)I)F)O

1 reference

PubChem ^Béarla

PubChem CID ^Béarla

Cobimetinib (Béarla)

19 Samhain 2016

C1CCN[C@@H](C1)C2(CN(C2)C(=O)C3=C(C(=C(C=C3)F)F)NC4=C(C=C(C=C4)I)F)O

1 reference

PubChem ^Béarla

PubChem CID ^Béarla

Cobimetinib (Béarla)

19 Samhain 2016

active ingredient in ^Béarla

Cotellic ^Béarla

1 reference

RxNorm ^Béarla

RxNorm ID ^Béarla

1722371

14 Feabhra 2018

World Health Organisation international non-proprietary name ^Béarla

cobimetinib (Béarla)

1 reference

ChEBI ^Béarla

ChEBI ID ^Béarla

cobimetinib (Béarla)

19 Deireadh Fómhair 2016

spriocghalar

metastatic melanoma ^Béarla

1 reference

Drug Indications Extracted from FAERS ^Béarla

2 Deireadh Fómhair 2018

meileanóma

1 reference

Drug Indications Extracted from FAERS ^Béarla

2 Deireadh Fómhair 2018

physically interacts with ^Béarla

Mitogen-activated protein kinase kinase 1 ^Béarla

allosteric modulator ^Béarla

1 reference

17 Lúnasa 2016

Mitogen-activated protein kinase kinase 2 ^Béarla

allosteric modulator ^Béarla

1 reference

17 Lúnasa 2016

mitogen-activated protein kinase kinase 7 ^Béarla

allosteric modulator ^Béarla

1 reference

17 Lúnasa 2016

Mitogen-activated protein kinase kinase 1 ^Béarla

reaction inhibitor ^Béarla

1 reference

Open Targets Platform ^Béarla

https://platform.opentargets.org/drug/CHEMBL2146883

14 Lúnasa 2023

URL tagartha

pregnancy category ^Béarla

Australian pregnancy category D ^Béarla

1 reference

iompórtáilte ó thionscadal Vicipéide

Vicipéid an Bhéarla

LiverTox likelihood score ^Béarla

LiverTox toxicity likelihood category D ^Béarla

1 reference

LiverTox ^Béarla

https://www.ncbi.nlm.nih.gov/books/n/livertox/Cobimetinib

8 Aibreán 2021

URL tagartha

last update ^Béarla

1 Meitheamh 2017

protein kinase inhibitors ^Béarla

1 reference

NDF-RT ^Béarla

NDF-RT ID ^Béarla

N0000192139

InChI=1S/C21H21F3IN3O2/c22-14-6-5-13(19(18(14)24)27-16-7-4-12(25)9-15(16)23)20(29)28-10-21(30,11-28)17-3-1-2-8-26-17/h4-7,9,17,26-27,30H,1-3,8,10-11H2/t17-/m0/s1

5 Márta 2018

Identifiers

InChI

1 reference

PubChem ^Béarla

PubChem CID ^Béarla

Cobimetinib (Béarla)

BSMCAPRUBJMWDF-KRWDZBQOSA-N

19 Samhain 2016

InChIKey ^Béarla

2 references

PubChem ^Béarla

PubChem CID ^Béarla

Cobimetinib (Béarla)

19 Samhain 2016

ChEBI release 2020-09-01 ^Béarla

uimhir CAS

934660-93-2

2 references

UNII ^Béarla

cobimetinib (Béarla)

BSMCAPRUBJMWDF-KRWDZBQOSA-N

19 Samhain 2016

InChIKey ^Béarla

CAS Common Chemistry ^Béarla

https://commonchemistry.cas.org/detail?cas_rn=934660-93-2

10 Aibreán 2021

URL tagartha

ChemSpider ID ^Béarla

17349374

1 reference

ChemSpider ^Béarla

ChemSpider ID ^Béarla

17349374

Cobimetinib (Béarla)

19 Samhain 2016

PubChem CID ^Béarla

1 reference

PubChem ^Béarla

PubChem CID ^Béarla

Cobimetinib (Béarla)

19 Samhain 2016

Reaxys registry number ^Béarla

12883594

1 reference

ChEBI ^Béarla

ChEBI ID ^Béarla

cobimetinib (Béarla)

19 Deireadh Fómhair 2016

ChEBI ID ^Béarla

mapping relation type ^Béarla

exact match ^Béarla

1 reference

ChEBI ^Béarla

ChEBI ID ^Béarla

cobimetinib (Béarla)

19 Deireadh Fómhair 2016

ChEMBL ID ^Béarla

CHEMBL2146883

1 reference

ChEMBL ^Béarla

ChEMBL ID ^Béarla

CHEMBL2146883

COBIMETINIB (Béarla)

bunaithe ar chur chuige heorastúil

19 Samhain 2016

SureChEMBL ID ^Béarla

SCHEMBL189565

1 reference

inferred from InChIKey ^Béarla

UniChem compound ID ^Béarla

27308527

1 reference

UniChem ^Béarla

DSSTox substance ID ^Béarla

DTXSID60239435

1 reference

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard ^Béarla

DSSTOX compound identifier ^Béarla

DTXCID80161926

0 references

LiverTox ID ^Béarla

Cobimetinib

0 references

ATC code ^Béarla

L01XE38

0 references

1 reference

cobimetinib (Béarla)

19 Samhain 2016

RxNorm ID ^Béarla

1722365

1 reference

UNII ^Béarla

cobimetinib (Béarla)

19 Samhain 2016

DrugBank ID ^Béarla

05239

1 reference

DrugBank ^Béarla

DrugBank ID ^Béarla

05239

Cobimetinib (Béarla)

19 Samhain 2016

UNII ^Béarla

1 reference

UNII ^Béarla

cobimetinib (Béarla)

19 Samhain 2016

MedlinePlus drug identifier ^Béarla

a615057

0 references

NDF-RT ID ^Béarla

N0000192139

1 reference

UNII ^Béarla

cobimetinib (Béarla)

19 Samhain 2016

Probes And Drugs ID ^Béarla

PD009336

0 references

DrugCentral ID ^Béarla

5046

1 reference

UniChem ^Béarla

KEGG ID ^Béarla

D10405

1 reference

ChEBI ^Béarla

ChEBI ID ^Béarla

cobimetinib (Béarla)

19 Deireadh Fómhair 2016

PDB ligand ID ^Béarla

EUI

0 references

Freebase ID ^Béarla

/m/0wqyv0d

0 references

Microsoft Academic ID ^Béarla

2779385430

0 references

PDB structure ID ^Béarla

4LMN

1 reference

Protein Data Bank ^Béarla

PDB structure ID ^Béarla

4LMN

4LMN (Béarla)

19 Deireadh Fómhair 2016

4AN2

1 reference

Protein Data Bank ^Béarla

PDB structure ID ^Béarla

4AN2

4AN2 (Béarla)

19 Deireadh Fómhair 2016

UMLS CUI ^Béarla

C4049146

1 reference

UNII ^Béarla

cobimetinib (Béarla)