Potassium voltage-gated channel subfamily E regulatory subunit 1 (Q1500343)

http://www.ebi.ac.uk/interpro/protein/P15382

1 reference

20 December 2017

1 reference

20 December 2017

potassium channel activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

delayed rectifier potassium channel activity

IEA

7 references

26 September 2017

A KCNQ1 mutation contributes to the concealed type 1 long QT phenotype by limiting the Kv7.1 channel conformational changes associated with protein kinase A phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

26 September 2017

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

26 September 2017

Mutations in the hminK gene cause long QT syndrome and suppress IKs function

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

26 September 2017

Augmented potassium current is a shared phenotype for two genetic defects associated with familial atrial fibrillation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

26 September 2017

Cellular dysfunction of LQT5-minK mutants: abnormalities of IKs, IKr and trafficking in long QT syndrome

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

26 September 2017

AKAP proteins anchor cAMP-dependent protein kinase to KvLQT1/IsK channel complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

26 September 2017

KCNQ1 gain-of-function mutation in familial atrial fibrillation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization

1 reference

8 April 2019

Cellular dysfunction of LQT5-minK mutants: abnormalities of IKs, IKr and trafficking in long QT syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

voltage-gated ion channel activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

1 reference

8 April 2019

Specific interaction of the potassium channel beta-subunit minK with the sarcomeric protein T-cap suggests a T-tubule-myofibril linking system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

potassium channel regulator activity

IPI

5 references

26 September 2017

Regulation of the Kv2.1 potassium channel by MinK and MiRP1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

26 September 2017

Cloning and function of the rat colonic epithelial K+ channel KVLQT1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

26 September 2017

Cellular dysfunction of LQT5-minK mutants: abnormalities of IKs, IKr and trafficking in long QT syndrome

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

26 September 2017

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

26 September 2017

KCNQ1 gain-of-function mutation in familial atrial fibrillation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

6 references

8 April 2019

KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

Analysis of the interactions between the C-terminal cytoplasmic domains of KCNQ1 and KCNE1 channel subunits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

Impact of KCNE subunits on KCNQ1 (Kv7.1) channel membrane surface targeting

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

Long QT mutations at the interface between KCNQ1 helix C and KCNE1 disrupt I(KS) regulation by PKA and PIP₂

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

Intracellular domains interactions and gated motions of I(KS) potassium channel subunits

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

Specific interaction of the potassium channel beta-subunit minK with the sarcomeric protein T-cap suggests a T-tubule-myofibril linking system

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

IPI

1 reference

26 September 2017

Mutations in the hminK gene cause long QT syndrome and suppress IKs function

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

delayed rectifier potassium channel activity

8 references

8 April 2019

A KCNQ1 mutation contributes to the concealed type 1 long QT phenotype by limiting the Kv7.1 channel conformational changes associated with protein kinase A phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

Cellular dysfunction of LQT5-minK mutants: abnormalities of IKs, IKr and trafficking in long QT syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

KCNQ1 gain-of-function mutation in familial atrial fibrillation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

Mutations in the hminK gene cause long QT syndrome and suppress IKs function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

Augmented potassium current is a shared phenotype for two genetic defects associated with familial atrial fibrillation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

AKAP proteins anchor cAMP-dependent protein kinase to KvLQT1/IsK channel complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

potassium channel regulator activity

6 references

8 April 2019

Cloning and function of the rat colonic epithelial K+ channel KVLQT1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

Regulation of the Kv2.1 potassium channel by MinK and MiRP1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

Cellular dysfunction of LQT5-minK mutants: abnormalities of IKs, IKr and trafficking in long QT syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

KCNQ1 gain-of-function mutation in familial atrial fibrillation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

transmembrane transporter binding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

integral component of membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

2 references

voltage-gated potassium channel complex

4 references

26 September 2017

Regulation of the Kv2.1 potassium channel by MinK and MiRP1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

26 September 2017

The KCNQ1 potassium channel is down-regulated by ubiquitylating enzymes of the Nedd4/Nedd4-like family

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

26 September 2017

Augmented potassium current is a shared phenotype for two genetic defects associated with familial atrial fibrillation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

26 September 2017

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

4 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

26 September 2017

Regulation of the Kv2.1 potassium channel by MinK and MiRP1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

26 September 2017

Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

1 reference

8 April 2019

Cellular dysfunction of LQT5-minK mutants: abnormalities of IKs, IKr and trafficking in long QT syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

1 reference

8 April 2019

Specific interaction of the potassium channel beta-subunit minK with the sarcomeric protein T-cap suggests a T-tubule-myofibril linking system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

1 reference

26 September 2017

Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

1 reference

8 April 2019

Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

Regulation of the Kv2.1 potassium channel by MinK and MiRP1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

voltage-gated potassium channel complex

HDA

5 references

8 April 2019

Regulation of the Kv2.1 potassium channel by MinK and MiRP1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

Augmented potassium current is a shared phenotype for two genetic defects associated with familial atrial fibrillation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

The KCNQ1 potassium channel is down-regulated by ubiquitylating enzymes of the Nedd4/Nedd4-like family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

regulation of ion transmembrane transport

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

protein O-linked glycosylation

IEA

1 reference

26 September 2017

O-glycosylation of the cardiac I(Ks) complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

ventricular cardiac muscle cell action potential

1 reference

26 September 2017

Mutations in the hminK gene cause long QT syndrome and suppress IKs function

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

cardiac muscle cell action potential involved in contraction

1 reference

8 April 2019

Cellular dysfunction of LQT5-minK mutants: abnormalities of IKs, IKr and trafficking in long QT syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

sensory perception of sound

1 reference

8 April 2019

A novel mutation in the potassium channel gene KVLQT1 causes the Jervell and Lange-Nielsen cardioauditory syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

TAS

membrane repolarization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

negative regulation of protein targeting to membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

membrane repolarization during action potential

ISS

3 references

26 September 2017

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

26 September 2017

AKAP proteins anchor cAMP-dependent protein kinase to KvLQT1/IsK channel complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

26 September 2017

Augmented potassium current is a shared phenotype for two genetic defects associated with familial atrial fibrillation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

regulation of delayed rectifier potassium channel activity

1 reference

8 April 2019

Cellular dysfunction of LQT5-minK mutants: abnormalities of IKs, IKr and trafficking in long QT syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

potassium ion transmembrane transport

TAS

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

Mutations in the hminK gene cause long QT syndrome and suppress IKs function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

AKAP proteins anchor cAMP-dependent protein kinase to KvLQT1/IsK channel complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

positive regulation of potassium ion transmembrane transport

1 reference

8 April 2019

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

protein N-linked glycosylation

1 reference

26 September 2017

O-glycosylation of the cardiac I(Ks) complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

membrane repolarization during cardiac muscle cell action potential

regulation of heart rate by cardiac conduction

1 reference

26 September 2017

Cellular dysfunction of LQT5-minK mutants: abnormalities of IKs, IKr and trafficking in long QT syndrome

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

regulation of potassium ion transmembrane transport

1 reference

8 April 2019

Cellular dysfunction of LQT5-minK mutants: abnormalities of IKs, IKr and trafficking in long QT syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

negative regulation of delayed rectifier potassium channel activity

1 reference

26 September 2017

Regulation of the Kv2.1 potassium channel by MinK and MiRP1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

cellular response to cAMP

1 reference

8 April 2019

AKAP proteins anchor cAMP-dependent protein kinase to KvLQT1/IsK channel complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

regulation of ventricular cardiac muscle cell membrane repolarization

1 reference

26 September 2017

Mutations in the hminK gene cause long QT syndrome and suppress IKs function

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

membrane repolarization during ventricular cardiac muscle cell action potential

1 reference

8 April 2019

Mutations in the hminK gene cause long QT syndrome and suppress IKs function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382

membrane repolarization during action potential

IEA

4 references

8 April 2019

Augmented potassium current is a shared phenotype for two genetic defects associated with familial atrial fibrillation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

AKAP proteins anchor cAMP-dependent protein kinase to KvLQT1/IsK channel complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

potassium ion export across plasma membrane

4 references

8 April 2019

The KCNQ1 potassium channel is down-regulated by ubiquitylating enzymes of the Nedd4/Nedd4-like family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

Cellular dysfunction of LQT5-minK mutants: abnormalities of IKs, IKr and trafficking in long QT syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382