SMAD family member 2 (Q14903951)

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mammalian protein found in Mus musculus
  • Smad2
  • mad-related protein 2
  • mothers against decapentaplegic homolog 2
  • MAD homolog 2
  • mMad2
  • Smad 2
  • mothers against DPP homolog 2
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Language Label Description Also known as
English
SMAD family member 2
mammalian protein found in Mus musculus
  • Smad2
  • mad-related protein 2
  • mothers against decapentaplegic homolog 2
  • MAD homolog 2
  • mMad2
  • Smad 2
  • mothers against DPP homolog 2

Statements

molecular function
protein binding
determination method
IPI
6 references
retrieved
14 February 2019
stated in
Activin regulation of the follicle-stimulating hormone beta-subunit gene involves Smads and the TALE homeodomain proteins Pbx1 and Prep1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62432
determination method
IPI
retrieved
14 February 2019
stated in
Induction of vascular smooth muscle alpha-actin gene transcription in transforming growth factor beta1-activated myofibroblasts mediated by dynamic interplay between the Pur repressor proteins and Sp1/Smad coactivators
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62432
determination method
IPI
retrieved
14 February 2019
stated in
Smicl is a novel Smad interacting protein and cleavage and polyadenylation specificity factor associated protein
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62432
determination method
IPI
retrieved
14 February 2019
stated in
Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62432
determination method
IPI
retrieved
14 February 2019
stated in
Identification of novel Smad binding proteins
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62432
determination method
IPI
retrieved
14 February 2019
stated in
Intercellular variation in signaling through the TGF-β pathway and its relation to cell density and cell cycle phase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62432
determination method
IPI
cell component
nucleus
determination method
IDA
IEA
ISO
7 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62432
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q62432
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62432
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62432
determination method
IEA
retrieved
14 February 2019
stated in
Smad proteins function as co-modulators for MEF2 transcriptional regulatory proteins
GOA
curator
UniProt
UniProt protein ID
Q62432
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62432
determination method
IDA
retrieved
14 February 2019
stated in
Proper formation of whisker barrelettes requires periphery-derived Smad4-dependent TGF-beta signaling
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62432
determination method
IDA
retrieved
14 February 2019
stated in
TGFbeta3 signaling activates transcription of the LEF1 gene to induce epithelial mesenchymal transformation during mouse palate development
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62432
determination method
IDA
retrieved
14 February 2019
stated in
Pin1 promotes degradation of Smad proteins and their interaction with phosphorylated tau in Alzheimer's disease
GOA
curator
ARUK-UCL
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62432
determination method
IDA
biological process
transforming growth factor beta receptor signaling pathway
determination method
IDA
IGI
IEA
ISO
6 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62432
determination method
ISO
retrieved
14 February 2019
stated in
Chromatin-bound p53 anchors activated Smads and the mSin3A corepressor to confer transforming-growth-factor-beta-mediated transcription repression
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62432
determination method
IGI
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62432
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62432
determination method
IEA
retrieved
14 February 2019
stated in
Endogenous TGF-beta signaling suppresses maturation of osteoblastic mesenchymal cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62432
determination method
IDA
retrieved
14 February 2019
stated in
Antagonistic effects of Smad2 versus Smad7 are sensitive to their expression level during tooth development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62432
determination method
IDA
positive regulation of transcription by RNA polymerase II
determination method
IDA
IGI
IEA
ISO
6 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62432
determination method
ISO
retrieved
14 February 2019
stated in
Foxh1 recruits Gsc to negatively regulate Mixl1 expression during early mouse development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62432
determination method
IGI
retrieved
14 February 2019
stated in
Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62432
determination method
IGI
retrieved
14 February 2019
stated in
TGF-β/Smad2/3 signaling directly regulates several miRNAs in mouse ES cells and early embryos
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62432
determination method
IGI
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62432
determination method
IEA
retrieved
14 February 2019
stated in
Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62432
determination method
IDA

Identifiers

 
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