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Bone morphogenetic protein 4 (Q14903410)

From Wikidata
mammalian protein found in Mus musculus
  • bone morphogenetic protein 2B
  • Bmp4
  • bone morphogenetic protein 4
  • BMP-2B
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    English
    Bone morphogenetic protein 4
    mammalian protein found in Mus musculus
    • bone morphogenetic protein 2B
    • Bmp4
    • bone morphogenetic protein 4
    • BMP-2B

    Statements

    molecular function
    protein binding
    determination method or standard
    IPI
    6 references
    retrieved
    14 February 2019
    stated in
    LRP2/megalin is required for patterning of the ventral telencephalon
    GOA
    curator
    UniProt
    UniProt protein ID
    P21275
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21275
    determination method or standard
    IPI
    retrieved
    14 February 2019
    stated in
    Developmentally regulated expression of mouse HtrA3 and its role as an inhibitor of TGF-beta signaling
    GOA
    curator
    UniProt
    UniProt protein ID
    P21275
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21275
    determination method or standard
    IPI
    retrieved
    14 February 2019
    stated in
    BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiation
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21275
    determination method or standard
    IPI
    retrieved
    14 February 2019
    stated in
    A novel chordin-like BMP inhibitor, CHL2, expressed preferentially in chondrocytes of developing cartilage and osteoarthritic joint cartilage
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21275
    determination method or standard
    IPI
    retrieved
    14 February 2019
    stated in
    HtrA1 serine protease inhibits signaling mediated by Tgfbeta family proteins
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21275
    determination method or standard
    IPI
    retrieved
    14 February 2019
    stated in
    Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21275
    determination method or standard
    IPI
    cell component
    biological process
    BMP signaling pathway
    determination method or standard
    IDA
    IGI
    ISS
    IEA
    ISO
    6 references
    retrieved
    24 April 2018
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    P21275
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P21275&geneProductId=UniProtKB:P21275
    determination method or standard
    ISS
    retrieved
    24 April 2018
    stated in
    Repulsive guidance molecule RGMa alters utilization of bone morphogenetic protein (BMP) type II receptors by BMP2 and BMP4
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P21275&geneProductId=UniProtKB:P21275
    determination method or standard
    ISO
    retrieved
    24 April 2018
    stated in
    Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P21275&geneProductId=UniProtKB:P21275
    determination method or standard
    IGI
    retrieved
    24 April 2018
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P21275&geneProductId=UniProtKB:P21275
    determination method or standard
    IEA
    retrieved
    24 April 2018
    stated in
    Repulsive guidance molecule RGMa alters utilization of bone morphogenetic protein (BMP) type II receptors by BMP2 and BMP4
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P21275&geneProductId=UniProtKB:P21275
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P21275&geneProductId=UniProtKB:P21275
    determination method or standard
    IDA
    positive regulation of transcription by RNA polymerase II
    determination method or standard
    IDA
    IGI
    IEA
    IMP
    ISO
    16 references
    retrieved
    14 February 2019
    stated in
    Bone morphogenetic proteins (BMPs) as regulators of dorsal forebrain development
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21275
    determination method or standard
    ISO
    retrieved
    14 February 2019
    stated in
    Changes in homeobox-containing gene expression during ectopic bone formation induced by bone morphogenetic protein
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21275
    determination method or standard
    ISO
    retrieved
    14 February 2019
    stated in
    Bmp4 is required for tracheal formation: a novel mouse model for tracheal agenesis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21275
    determination method or standard
    IMP
    retrieved
    14 February 2019
    stated in
    Bmp4 signaling is required for outflow-tract septation and branchial-arch artery remodeling
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21275
    determination method or standard
    IMP
    retrieved
    14 February 2019
    stated in
    Msx1 controls inductive signaling in mammalian tooth morphogenesis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21275
    determination method or standard
    IGI
    retrieved
    14 February 2019
    stated in
    Msx1 is required for the induction of Patched by Sonic hedgehog in the mammalian tooth germ
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21275
    determination method or standard
    IGI
    retrieved
    14 February 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21275
    determination method or standard
    IEA
    retrieved
    14 February 2019
    stated in
    FGF-, BMP- and Shh-mediated signalling pathways in the regulation of cranial suture morphogenesis and calvarial bone development
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21275
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    Teashirt 3 is necessary for ureteral smooth muscle differentiation downstream of SHH and BMP4
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21275
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    Msx1 controls inductive signaling in mammalian tooth morphogenesis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21275
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    Bmp4 is required for tracheal formation: a novel mouse model for tracheal agenesis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21275
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    Id genes are direct targets of bone morphogenetic protein induction in embryonic stem cells
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21275
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    Molecular mechanisms of cell and tissue interactions during early tooth development
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21275
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    Murine cerberus homologue mCer-1: a candidate anterior patterning molecule
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21275
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21275
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    Two BMP responsive elements, STAT, and bZIP/HNF4/COUP motifs of the hepcidin promoter are critical for BMP, SMAD1, and HJV responsiveness
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21275
    determination method or standard
    IDA
    BMP signaling pathway
    determination method or standard
    IBA
    IDA
    IEA
    IGI
    ISO
    ISS
    7 references
    retrieved
    14 February 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    P21275
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21275
    determination method or standard
    ISS
    retrieved
    14 February 2019
    stated in
    Repulsive guidance molecule RGMa alters utilization of bone morphogenetic protein (BMP) type II receptors by BMP2 and BMP4
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21275
    determination method or standard
    ISO
    retrieved
    14 February 2019
    stated in
    Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21275
    determination method or standard
    IGI
    retrieved
    14 February 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21275
    determination method or standard
    IEA
    retrieved
    14 February 2019
    stated in
    Repulsive guidance molecule RGMa alters utilization of bone morphogenetic protein (BMP) type II receptors by BMP2 and BMP4
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21275
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21275
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21275
    determination method or standard
    IBA

    Identifiers

     
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