Glyceraldehyde-3-phosphate dehydrogenase (Q424886)

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mammalian protein found in Homo sapiens

• glyceraldehyde-3-phosphate dehydrogenase
• peptidyl-cysteine S-nitrosylase GAPDH
• OCAS, p38 component
• epididymis secretory sperm binding protein Li 162eP
• 2.6.99.-
• GAPDH
• aging-associated gene 9 protein
• Oct1 coactivator in S phase, 38 Kd component

edit

Language	Label	Description	Also known as
English	Glyceraldehyde-3-phosphate dehydrogenase	mammalian protein found in Homo sapiens	glyceraldehyde-3-phosphate dehydrogenase peptidyl-cysteine S-nitrosylase GAPDH OCAS, p38 component epididymis secretory sperm binding protein Li 162eP 2.6.99.- GAPDH aging-associated gene 9 protein Oct1 coactivator in S phase, 38 Kd component

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P04406

part of

NAD(P)-binding domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P04406

Glyceraldehyde-3-phosphate dehydrogenase, type I

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P04406

Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Glyceraldehyde 3-phosphate dehydrogenase, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

image

3gpd3.jpg
1,000 × 797; 397 KB

0 references

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P04406

encoded by

GAPDH

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P04406

molecular function

transferase activity

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IEA

microtubule binding

determination method

ISS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

ISS

NAD binding

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IEA

oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IEA

protein binding

determination method

IPI

15 references

retrieved

8 April 2019

stated in

A mutation in human VAP-B--MSP domain, present in ALS patients, affects the interaction with other cellular proteins

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IPI

retrieved

8 April 2019

stated in

Glyceraldehyde-3-phosphate dehydrogenase is phosphorylated by protein kinase Ciota /lambda and plays a role in microtubule dynamics in the early secretory pathway

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IPI

retrieved

8 April 2019

stated in

Oxidative stress-responsive intracellular regulation specific for the angiostatic form of human tryptophanyl-tRNA synthetase

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IPI

retrieved

8 April 2019

stated in

A human protein-protein interaction network: a resource for annotating the proteome

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IPI

retrieved

8 April 2019

stated in

Dynamic profiling of the post-translational modifications and interaction partners of epidermal growth factor receptor signaling after stimulation by epidermal growth factor using Extended Range Proteomic Analysis (ERPA)

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IPI

retrieved

8 April 2019

stated in

A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling.

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IPI

retrieved

8 April 2019

stated in

Prolyl oligopeptidase is a glyceraldehyde-3-phosphate dehydrogenase-binding protein that regulates genotoxic stress-induced cell death

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IPI

retrieved

8 April 2019

stated in

The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IPI

retrieved

8 April 2019

stated in

Loose interaction between glyceraldehyde-3-phosphate dehydrogenase and phosphoglycerate kinase revealed by fluorescence resonance energy transfer-fluorescence lifetime imaging microscopy in living cells

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IPI

retrieved

8 April 2019

stated in

Target-selective protein S-nitrosylation by sequence motif recognition

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IPI

retrieved

8 April 2019

stated in

Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IPI

retrieved

8 April 2019

stated in

Systematic Analysis Reveals Elongation Factor 2 and α-Enolase as Novel Interaction Partners of AKT2

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IPI

retrieved

8 April 2019

stated in

Proliferating cell nuclear antigen in the cytoplasm interacts with components of glycolysis and cancer

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IPI

retrieved

8 April 2019

stated in

Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IPI

retrieved

8 April 2019

stated in

Identification of sperm head proteins involved in zona pellucida binding

GOA

curator

Critical Assessment of Protein Function Annotation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IPI

peptidyl-cysteine S-nitrosylase activity

determination method

ISS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

ISS

NADP binding

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IEA

identical protein binding

determination method

IPI

2 references

retrieved

8 April 2019

stated in

Loose interaction between glyceraldehyde-3-phosphate dehydrogenase and phosphoglycerate kinase revealed by fluorescence resonance energy transfer-fluorescence lifetime imaging microscopy in living cells

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IPI

retrieved

8 April 2019

stated in

Toward an understanding of the protein interaction network of the human liver

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IPI

oxidoreductase activity

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IEA

glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity

determination method

NAS

ISS

IEA

EXP

6 references

retrieved

31 October 2017

stated in

The complete amino acid sequence of human muscle glyceraldehyde 3-phosphate dehydrogenase

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

NAS

retrieved

31 October 2017

stated in

Isolation and complete sequence of a functional human glyceraldehyde-3-phosphate dehydrogenase gene

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

NAS

retrieved

31 October 2017

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

ISS

retrieved

31 October 2017

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

IEA

retrieved

31 October 2017

stated in

Glyceraldehyde-3-phosphate dehydrogenase from human tissues

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

EXP

retrieved

31 October 2017

stated in

Isolation and complete sequence of a functional human glyceraldehyde-3-phosphate dehydrogenase gene

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

EXP

aspartic-type endopeptidase inhibitor activity

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

A peptide derived from the highly conserved protein GAPDH is involved in tissue protection by different antifungal strategies and epithelial immunomodulation

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IDA

disordered domain specific binding

determination method

IPI

1 reference

retrieved

8 April 2019

stated in

HSP90, HSP70, and GAPDH directly interact with the cytoplasmic domain of macrophage scavenger receptors

GOA

curator

Critical Assessment of Protein Function Annotation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IPI

glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity

determination method

EXP

IBA

IEA

ISS

NAS

7 references

retrieved

1 January 2018

stated in

The complete amino acid sequence of human muscle glyceraldehyde 3-phosphate dehydrogenase

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

NAS

retrieved

1 January 2018

stated in

Isolation and complete sequence of a functional human glyceraldehyde-3-phosphate dehydrogenase gene

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

NAS

retrieved

1 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

ISS

retrieved

1 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

IEA

retrieved

1 January 2018

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

IBA

retrieved

1 January 2018

stated in

Glyceraldehyde-3-phosphate dehydrogenase from human tissues

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

EXP

retrieved

1 January 2018

stated in

Isolation and complete sequence of a functional human glyceraldehyde-3-phosphate dehydrogenase gene

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

EXP

glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity

determination method

IBA

IEA

ISS

NAS

5 references

retrieved

8 April 2019

stated in

The complete amino acid sequence of human muscle glyceraldehyde 3-phosphate dehydrogenase

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

NAS

retrieved

8 April 2019

stated in

Isolation and complete sequence of a functional human glyceraldehyde-3-phosphate dehydrogenase gene

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

NAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

ISS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IBA

cell component

vesicle

determination method

IDA

1 reference

retrieved

31 October 2017

stated in

Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

IDA

nuclear membrane

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Human Protein Atlas

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IDA

membrane

determination method

IDA

IEA

2 references

retrieved

31 October 2017

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

IEA

retrieved

31 October 2017

stated in

Defining the membrane proteome of NK cells

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

IDA

intracellular membrane-bounded organelle

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Human Protein Atlas

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IDA

microtubule cytoskeleton

determination method

ISS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

ISS

lipid droplet

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

Identification of major proteins in the lipid droplet-enriched fraction isolated from the human hepatocyte cell line HuH7

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IDA

plasma membrane

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Human Protein Atlas

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IDA

perinuclear region of cytoplasm

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IEA

GAIT complex

determination method

IDA

2 references

retrieved

8 April 2019

stated in

Heterotrimeric GAIT complex drives transcript-selective translation inhibition in murine macrophages

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IDA

retrieved

8 April 2019

stated in

Noncanonical function of glutamyl-prolyl-tRNA synthetase: gene-specific silencing of translation

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IDA

cytoskeleton

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IEA

extracellular exosome

determination method

IDA

8 references

retrieved

31 October 2017

stated in

Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

IDA

retrieved

31 October 2017

stated in

Intestinal epithelial cells secrete exosome-like vesicles

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

IDA

retrieved

31 October 2017

stated in

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

IDA

retrieved

31 October 2017

stated in

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

IDA

retrieved

31 October 2017

stated in

Large-scale proteomics and phosphoproteomics of urinary exosomes

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

IDA

retrieved

31 October 2017

stated in

Protein profile of exosomes from trabecular meshwork cells

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

IDA

retrieved

31 October 2017

stated in

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

IDA

retrieved

31 October 2017

stated in

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

IDA

cytosol

determination method

TAS

ISS

IDA

IEA

5 references

retrieved

31 October 2017

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

TAS

retrieved

31 October 2017

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

ISS

retrieved

31 October 2017

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

IEA

retrieved

31 October 2017

stated in

Mitochondrial disulfide relay mediates translocation of p53 and partitions its subcellular activity

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

IDA

retrieved

31 October 2017

stated in

GOA

curator

Human Protein Atlas

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

IDA

nucleus

determination method

ISS

IDA

IEA

3 references

retrieved

31 October 2017

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

ISS

retrieved

31 October 2017

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

IEA

retrieved

31 October 2017

stated in

Proteomic characterization of the human sperm nucleus

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

IDA

extracellular matrix

determination method

IDA

1 reference

retrieved

31 October 2017

stated in

SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

IDA

cytoplasm

determination method

IDA

IEA

ISS

4 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

ISS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IEA

retrieved

8 April 2019

stated in

ERCC6L2 mutations link a distinct bone-marrow-failure syndrome to DNA repair and mitochondrial function

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IDA

retrieved

8 April 2019

stated in

HSP90, HSP70, and GAPDH directly interact with the cytoplasmic domain of macrophage scavenger receptors

GOA

curator

Critical Assessment of Protein Function Annotation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IDA

nucleus

determination method

HDA

IEA

ISS

3 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

ISS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IEA

retrieved

8 April 2019

stated in

Proteomic characterization of the human sperm nucleus

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

HDA

cytosol

determination method

IBA

IDA

IEA

ISS

TAS

6 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

ISS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IEA

retrieved

8 April 2019

stated in

Mitochondrial disulfide relay mediates translocation of p53 and partitions its subcellular activity

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IDA

retrieved

8 April 2019

stated in

GOA

curator

Human Protein Atlas

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IBA

membrane

determination method

HDA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IEA

retrieved

8 April 2019

stated in

Defining the membrane proteome of NK cells

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

HDA

vesicle

determination method

HDA

1 reference

retrieved

8 April 2019

stated in

Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

HDA

extracellular exosome

determination method

HDA

7 references

retrieved

8 April 2019

stated in

Protein profile of exosomes from trabecular meshwork cells

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

HDA

retrieved

8 April 2019

stated in

Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

HDA

retrieved

8 April 2019

stated in

Large-scale proteomics and phosphoproteomics of urinary exosomes

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

HDA

retrieved

8 April 2019

stated in

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

HDA

retrieved

8 April 2019

stated in

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

HDA

retrieved

8 April 2019

stated in

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

HDA

retrieved

8 April 2019

stated in

Intestinal epithelial cells secrete exosome-like vesicles

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

HDA

ribonucleoprotein complex

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

Noncanonical function of glutamyl-prolyl-tRNA synthetase: gene-specific silencing of translation

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IDA

biological process

peptidyl-cysteine S-trans-nitrosylation

determination method

ISS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

ISS

neuron apoptotic process

determination method

ISS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

ISS

gluconeogenesis

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

TAS

negative regulation of translation

determination method

IDA

IMP

2 references

retrieved

8 April 2019

stated in

Noncanonical function of glutamyl-prolyl-tRNA synthetase: gene-specific silencing of translation

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IMP

retrieved

8 April 2019

stated in

Heterotrimeric GAIT complex drives transcript-selective translation inhibition in murine macrophages

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IDA

glycolytic process

determination method

IEA

1 reference

retrieved

31 October 2017

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04406&geneProductId=UniProtKB:P04406

determination method

IEA

canonical glycolysis

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

TAS

protein stabilization

determination method

ISS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

ISS

cellular response to interferon-gamma

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

Noncanonical function of glutamyl-prolyl-tRNA synthetase: gene-specific silencing of translation

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IDA

regulation of translation

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IEA

microtubule cytoskeleton organization

determination method

ISS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

ISS

regulation of macroautophagy

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

AMPK-Dependent Phosphorylation of GAPDH Triggers Sirt1 Activation and Is Necessary for Autophagy upon Glucose Starvation

GOA

curator

Parkinsons Disease Gene Ontology Initiative

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

TAS

apoptotic process

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IEA

glucose metabolic process

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IEA

negative regulation of endopeptidase activity

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

A peptide derived from the highly conserved protein GAPDH is involved in tissue protection by different antifungal strategies and epithelial immunomodulation

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IDA

antimicrobial humoral immune response mediated by antimicrobial peptide

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

A peptide derived from the highly conserved protein GAPDH is involved in tissue protection by different antifungal strategies and epithelial immunomodulation

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IDA

glycolytic process

determination method

IBA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04406

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04406

determination method

IBA

EC enzyme number

2.6.99.-

1 reference

retrieved

12 October 2015

reference URL

http://www.uniprot.org/uniprot/P04406.txt?206

stated in

UniProt

Gene Atlas image

PBB GE GAPDH 212581 x at fs.png
732 × 530; 12 KB

0 references

exact match

http://purl.uniprot.org/uniprot/P04406

1 reference

stated in

Identifiers.org

has part(s)

Glyceraldehyde 3-phosphate dehydrogenase, active site

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P04406

Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P04406

Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P04406

Commons category

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)

0 references

Identifiers

RefSeq protein ID

NP_001243728

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

2597

NP_001276674

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

2597

NP_001276675

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

2597

NP_002037

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

2597

NP_001344872

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

2597

UniProt protein ID

P04406

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P04406

Ensembl protein ID

ENSP00000229239

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000229239

ENSP00000380067

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000380067

ENSP00000380068

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000380068

ENSP00000380070

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000380070

ENSP00000478864

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000478864

ENSP00000380065

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000380065

Freebase ID

/m/0bwkhb

1 reference

stated in

Freebase Data Dumps

publication date

28 October 2013

Microsoft Academic ID

134792803

0 references

OpenAlex ID

C134792803

1 reference

stated in

OpenAlex

retrieved

26 January 2022

reference URL

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID

1U8F

1 reference

stated in

UniProt

UniProt protein ID

P04406

retrieved

15 June 2016

language of work or name

English

1ZNQ

1 reference

stated in

UniProt

UniProt protein ID

P04406

retrieved

15 June 2016

language of work or name

English

3GPD

1 reference

stated in

UniProt

UniProt protein ID

P04406

retrieved

15 June 2016

language of work or name

English

4WNC

1 reference

stated in

UniProt

UniProt protein ID

P04406

retrieved

15 June 2016

language of work or name

English

4WNI

1 reference

stated in

UniProt

UniProt protein ID

P04406

retrieved

15 June 2016

language of work or name

English

 

Sitelinks

Wikipedia(18 entries)

edit

• bgwiki Глицералдехид-3-фосфатдехидрогеназа
• cawiki Gliceraldehid-3-fosfat deshidrogenasa
• dewiki Glycerinaldehyd-3-phosphat-Dehydrogenase
• enwiki Glyceraldehyde 3-phosphate dehydrogenase
• eswiki Gliceraldehído-3-fosfato deshidrogenasa
• fawiki GAPDH
• fiwiki Glyseraldehydi-3-fosfaattidehydrogenaasi
• frwiki Glycéraldéhyde-3-phosphate déshydrogénase
• glwiki Gliceraldehido-3-fosfato deshidroxenase
• huwiki Glicerinaldehid-3-foszfát-dehidrogenáz
• idwiki Gliseraldehida 3-fosfat dehidrogenase
• itwiki Gliceraldeide-3-fosfato deidrogenasi (NADP+)
• kowiki 글리세르알데하이드 3-인산 탈수소효소
• mswiki Gliseraldehid 3-fosfat dehidrogenase
• plwiki Dehydrogenaza aldehydu 3-fosfoglicerynowego
• shwiki Gliceraldehid-3-fosfat dehidrogenaza
• srwiki Gliceraldehid-3-fosfat dehidrogenaza
• ukwiki Гліцеральдегід-3-фосфатдегідрогеназа

Wikibooks(0 entries)

edit

Wikinews(0 entries)

edit

Wikiquote(0 entries)

edit

Wikisource(0 entries)

edit

Wikiversity(0 entries)

edit

Wikivoyage(0 entries)

edit

Wiktionary(0 entries)

edit

Multilingual sites(1 entry)

edit

• commonswiki Category:Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q424886&oldid=2087966036"