Expression-based drug screening of neural progenitor cells from individuals with schizophrenia (Q57793573)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30356048%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

title

Expression-based drug screening of neural progenitor cells from individuals with schizophrenia (English)

1 reference

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30 April 2020

0 references

1 reference

corrigendum / erratum

Author Correction: Expression-based drug screening of neural progenitor cells from individuals with schizophrenia

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author

David Collier

4

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30 April 2020

Gabriel E Hoffman

8

1 reference

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30 April 2020

Eric E Schadt

11

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30 April 2020

Kristen J. Brennand

13

1 reference

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30 April 2020

9

Pamela Sklar

1 reference

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30 April 2020

author name string

Benjamin Readhead

1

1 reference

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30 April 2020

Brigham J Hartley

2

1 reference

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30 April 2020

Brian J Eastwood

3

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30 April 2020

David Evans

5

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30 April 2020

Richard Farias

6

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30 April 2020

Ching He

7

1 reference

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30 April 2020

Joel T Dudley

10

1 reference

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30 April 2020

Radoslav Savić

12

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30 April 2020

language of work or name

English

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publication date

24 October 2018

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30 April 2020

published in

Nature Communications

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30 April 2020

volume

9

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30 April 2020

issue

1

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30 April 2020

page(s)

4412

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A Library of Phosphoproteomic and Chromatin Signatures for Characterizing Cellular Responses to Drug Perturbations.

30 April 2020

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Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brains.

2 November 2018

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2 November 2018

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A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles.

2 November 2018

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Multifarious Functions of the Fragile X Mental Retardation Protein

2 November 2018

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Mutation intolerant genes and targets of FMRP are enriched for nonsynonymous alleles in schizophrenia

2 November 2018

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2 November 2018

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2 November 2018

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Human iPSC-Derived Neural Progenitors Are an Effective Drug Discovery Model for Neurological mtDNA Disorders.

2 November 2018

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Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens

2 November 2018

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variancePartition: interpreting drivers of variation in complex gene expression studies.

2 November 2018

1 reference

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Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

2 November 2018

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Systematic Quality Control Analysis of LINCS Data

2 November 2018

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Activity-Dependent Changes in Gene Expression in Schizophrenia Human-Induced Pluripotent Stem Cell Neurons

2 November 2018

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Gene expression elucidates functional impact of polygenic risk for schizophrenia

2 November 2018

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Establishment of Reporter Lines for Detecting Fragile X Mental Retardation (FMR1) Gene Reactivation in Human Neural Cells

2 November 2018

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Identification of consensus binding sites clarifies FMRP binding determinants

2 November 2018

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Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure

2 November 2018

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Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells

2 November 2018

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Altering the course of schizophrenia: progress and perspectives

2 November 2018

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Polygenic overlap between schizophrenia risk and antipsychotic response: a genomic medicine approach

2 November 2018

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Direct Lineage Reprogramming Reveals Disease-Specific Phenotypes of Motor Neurons from Human ALS Patients

2 November 2018

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2 November 2018

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Pluripotent stem cell-based disease modeling: current hurdles and future promise

2 November 2018

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2 November 2018

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Comparative neurotoxicity screening in human iPSC-derived neural stem cells, neurons and astrocytes

2 November 2018

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MicroRNA Profiling of Neurons Generated Using Induced Pluripotent Stem Cells Derived from Patients with Schizophrenia and Schizoaffective Disorder, and 22q11.2 Del.

2 November 2018

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Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture

2 November 2018

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A guide to generating and using hiPSC derived NPCs for the study of neurological diseases

2 November 2018

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limma powers differential expression analyses for RNA-sequencing and microarray studies

2 November 2018

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Evolving toward a human-cell based and multiscale approach to drug discovery for CNS disorders

2 November 2018

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2 November 2018

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Synaptic dysregulation in a human iPS cell model of mental disorders

2 November 2018

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2 November 2018

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Biological insights from 108 schizophrenia-associated genetic loci

2 November 2018

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Modeling a genetic risk for schizophrenia in iPSCs and mice reveals neural stem cell deficits associated with adherens junctions and polarity

2 November 2018

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2 November 2018

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Copy number variation in schizophrenia in Sweden

2 November 2018

1 reference

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Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia

2 November 2018

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Modeling hippocampal neurogenesis using human pluripotent stem cells

2 November 2018

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A polygenic burden of rare disruptive mutations in schizophrenia

2 November 2018

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De novo mutations in schizophrenia implicate synaptic networks

2 November 2018

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2 November 2018

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A hypothesis-driven association study of 28 nuclear-encoded mitochondrial genes with antipsychotic-induced weight gain in schizophrenia

2 November 2018

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Medication adherence in schizophrenia: factors influencing adherence and consequences of nonadherence, a systematic literature review

2 November 2018

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Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons

2 November 2018

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Does size matter in R&D productivity? If not, what does?

2 November 2018

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Opportunities and challenges of pluripotent stem cell neurodegenerative disease models

2 November 2018

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Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development.

2 November 2018

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A small molecule screen in stem-cell-derived motor neurons identifies a kinase inhibitor as a candidate therapeutic for ALS.

2 November 2018

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The translation of translational control by FMRP: therapeutic targets for FXS.

2 November 2018

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FMRP targets distinct mRNA sequence elements to regulate protein expression

2 November 2018

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SynSysNet: integration of experimental data on synaptic protein-protein interactions with drug-target relations

2 November 2018

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A system-level transcriptomic analysis of schizophrenia using postmortem brain tissue samples

2 November 2018

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World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Schizophrenia, part 1: update 2012 on the acute treatment of schizophrenia and the management of treatment resistance

2 November 2018

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Modeling human cortical development in vitro using induced pluripotent stem cells

2 November 2018

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De Novo Gene Disruptions in Children on the Autistic Spectrum

2 November 2018

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Data-driven prediction of drug effects and interactions

2 November 2018

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Strategies for aggregating gene expression data: the collapseRows R function

2 November 2018

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FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism

2 November 2018

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Neural circuit architecture defects in a Drosophila model of Fragile X syndrome are alleviated by minocycline treatment and genetic removal of matrix metalloproteinase

2 November 2018

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Modelling schizophrenia using human induced pluripotent stem cells

2 November 2018

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GAGE: generally applicable gene set enrichment for pathway analysis

2 November 2018

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Minocycline promotes dendritic spine maturation and improves behavioural performance in the fragile X mouse model

2 November 2018

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The evolution of drug development in schizophrenia: past issues and future opportunities

2 November 2018

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Induction of heat shock proteins in differentiated human and rodent neurons by celastrol

2 November 2018

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Clozapine treatment of childhood-onset schizophrenia: evaluation of effectiveness, adverse effects, and long-term outcome

2 November 2018

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Relating protein pharmacology by ligand chemistry

2 November 2018

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The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease

2 November 2018

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Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies

2 November 2018

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Erratum: Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

2 November 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FS41467-018-06515-4

inferred from DOI database lookup

7 January 2021

based on heuristic

KEGG-PATH: Kyoto encyclopedia of genes and genomes-based pathway analysis using a path analysis model

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FS41467-018-06515-4

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/S41467-018-06515-4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30356048%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30356048%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

PubMed publication ID

30356048

1 reference