(2R)-daptomycin &#160; Béarla (Q418747)

NDF-RT ^Béarla

NDF-RT ID ^Béarla

N0000148828

27 Feabhra 2018

biogenic cyclopeptide ^Béarla

0 references

1 reference

Daptomycin (Béarla)

DrugBank ^Béarla

dáta foilsithe

17 Samhain 2015

DrugBank ID ^Béarla

00080

struchtúr ceimiceach

Daptomycin Ball et al.svg
3,793 × 1,940; 11 KB

0 references

mais

1,619.710366 aonad maise adamhaí

1 reference

PubChem ^Béarla

PubChem CID ^Béarla

16134395

DAPTOMYCIN (Béarla)

5 Deireadh Fómhair 2016

stereoisomer of ^Béarla

decanoyl-Trp-Asn-Asp-Thr(1)-Gly-Orn-Asp-D-Ala-Asp-Gly-D-Ser-Glu(3S-Me)-Asp(Ph(2-NH2))-(1) ^Béarla

2 references

inferred from InChIKey ^Béarla

inferred from InChI ^Béarla

(2S)-daptomycin ^Béarla

2 references

inferred from InChIKey ^Béarla

inferred from InChI ^Béarla

foirmle cheimiceach

C₇₂H₁₀₁N₁₇O₂₆

1 reference

PubChem ^Béarla

PubChem CID ^Béarla

16134395

DAPTOMYCIN (Béarla)

5 Deireadh Fómhair 2016

SMILES canónta

CCCCCCCCCC(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CC(=O)N)C(=O)NC(CC(=O)O)C(=O)NC3C(OC(=O)C(NC(=O)C(NC(=O)C(NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)CNC3=O)CCCN)CC(=O)O)C)CC(=O)O)CO)C(C)CC(=O)O)CC(=O)C4=CC=CC=C4N)C

1 reference

PubChem ^Béarla

PubChem CID ^Béarla

16134395

DAPTOMYCIN (Béarla)

5 Deireadh Fómhair 2016

SMILES isiméireach

CCCCCCCCCC(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@H](CC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H]3[C@@H](C)OC(=O)[C@H](CC(=O)C4=C(N)C=CC=C4)NC(=O)[C@@H](NC(=O)[C@@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCN)NC(=O)CNC3=O)[C@H](C)CC(O)=O

1 reference

UNII ^Béarla

NWQ5N31VKK

15 Feabhra 2018

defined daily dose ^Béarla

0.28 gram

route of administration ^Béarla

parenteral route of administration ^Béarla

1 reference

https://www.whocc.no/atc_ddd_index/?code=J01XX09

active ingredient in ^Béarla

Cubicin ^Béarla

1 reference

RxNorm ^Béarla

RxNorm ID ^Béarla

404965

15 Feabhra 2018

World Health Organisation international non-proprietary name ^Béarla

daptomycin (Béarla)

2 references

ChEBI ^Béarla

ChEBI ID ^Béarla

600103

daptomycin (Béarla)

Streptomyces filamentosus

5 Deireadh Fómhair 2016

foilsithe i

Recommended INN: List 29 ^Béarla

dáta foilsithe

1989

tacsón ina n-aimsítear é

1 reference

Daptomycin biosynthesis in Streptomyces roseosporus: cloning and analysis of the gene cluster and revision of peptide stereochemistry ^Béarla

spriocghalar

staphylococcal infection ^Béarla

1 reference

2 Deireadh Fómhair 2018

infective endocarditis ^Béarla

1 reference

galar tógálach baictéarach

2 Deireadh Fómhair 2018

1 reference

2 Deireadh Fómhair 2018

Ceallailíteas

1 reference

2 Deireadh Fómhair 2018

septic arthritis ^Béarla

1 reference

2 Deireadh Fómhair 2018

ionfhabhtú craicinn

1 reference

2 Deireadh Fómhair 2018

staphylococcus aureus septicemia ^Béarla

am tosaigh

12 Meán Fómhair 2003

approved by ^Béarla

Riarachán Bia is Drugaí

1 reference

Inxight: Drugs Database ^Béarla

2 Samhain 2018

https://drugs.ncats.io/drug/NWQ5N31VKK

http://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021572s038lbl.pdf

galar tógálach baictéarach

am tosaigh

12 Meán Fómhair 2003

approved by ^Béarla

Riarachán Bia is Drugaí

1 reference

Inxight: Drugs Database ^Béarla

2 Samhain 2018

https://drugs.ncats.io/drug/NWQ5N31VKK

http://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021572s038lbl.pdf

significant drug interaction ^Béarla

rosuvastatin ^Béarla

side effect ^Béarla

rhabdomyolysis ^Béarla

1 reference

hypothetically ^Béarla

A reference set of clinically relevant adverse drug-drug interactions ^Béarla

simvastatin ^Béarla

side effect ^Béarla

rhabdomyolysis ^Béarla

1 reference

hypothetically ^Béarla

A reference set of clinically relevant adverse drug-drug interactions ^Béarla

atorvastatin ^Béarla

side effect ^Béarla

rhabdomyolysis ^Béarla

1 reference

hypothetically ^Béarla

A reference set of clinically relevant adverse drug-drug interactions ^Béarla

fluvastatin ^Béarla

side effect ^Béarla

rhabdomyolysis ^Béarla

1 reference

hypothetically ^Béarla

A reference set of clinically relevant adverse drug-drug interactions ^Béarla

pravastatin ^Béarla

side effect ^Béarla

rhabdomyolysis ^Béarla

1 reference

hypothetically ^Béarla

A reference set of clinically relevant adverse drug-drug interactions ^Béarla

rosuvastatin ^Béarla

side effect ^Béarla

muscular disease ^Béarla

1 reference

hypothetically ^Béarla

A reference set of clinically relevant adverse drug-drug interactions ^Béarla

simvastatin ^Béarla

side effect ^Béarla

muscular disease ^Béarla

1 reference

hypothetically ^Béarla

A reference set of clinically relevant adverse drug-drug interactions ^Béarla

atorvastatin ^Béarla

side effect ^Béarla

muscular disease ^Béarla

1 reference

hypothetically ^Béarla

A reference set of clinically relevant adverse drug-drug interactions ^Béarla

fluvastatin ^Béarla

side effect ^Béarla

muscular disease ^Béarla

1 reference

hypothetically ^Béarla

A reference set of clinically relevant adverse drug-drug interactions ^Béarla

pravastatin ^Béarla

side effect ^Béarla

muscular disease ^Béarla

1 reference

hypothetically ^Béarla

iompórtáilte ó thionscadal Vicipéide

A reference set of clinically relevant adverse drug-drug interactions ^Béarla

pregnancy category ^Béarla

US pregnancy category B ^Béarla

1 reference

1 reference

https://www.pfizer.com/products/product-list

cáilíocht

táirge íocshláinte bitheolaíocha

1 reference

Daptomycin (Béarla)

DrugBank ^Béarla

dáta foilsithe

17 Samhain 2015

DrugBank ID ^Béarla

1 reference

Medical Subject Headings ^Béarla

MeSH descriptor ID ^Béarla

15 Márta 2018

1 reference

ChEBI ^Béarla

ChEBI ID ^Béarla

600103

‎WHO Aware Classification ^Béarla

reserve ^Béarla

1 reference

2023 ‎AWaRe classification‎ ^Béarla

stylized name ^Béarla

DAPTOmycin

cáilíocht

Tall Man lettering ^Béarla

arna n-eisiúint ag

Institute for Safe Medication Practices ^Béarla

luaite mar

daptomycin

1 reference

https://www.ismp.org/recommendations/tall-man-letters-list

2 Meán Fómhair 2022

NCI Thesaurus ID ^Béarla

C47470

1 reference

UNII ^Béarla

NWQ5N31VKK

iompórtáilte ó thionscadal Vicipéide

15 Feabhra 2018

catagóir Commons

Daptomycin

0 references

Identifiers

ID GND

4555516-3

1 reference

Vicipéid na Gearmáinise

InChI

InChI=1S/C72H101N17O26/c1-5-6-7-8-9-10-11-22-53(93)81-44(25-38-31-76-42-20-15-13-17-39(38)42)66(108)84-45(27-52(75)92)67(109)86-48(30-59(102)103)68(110)89-61-37(4)115-72(114)49(26-51(91)40-18-12-14-19-41(40)74)87-71(113)60(35(2)24-56(96)97)88-69(111)50(34-90)82-55(95)32-77-63(105)46(28-57(98)99)83-62(104)36(3)79-65(107)47(29-58(100)101)85-64(106)43(21-16-23-73)80-54(94)33-78-70(61)112/h12-15,17-20,31,35-37,43-50,60-61,76,90H,5-11,16,21-30,32-34,73-74H2,1-4H3,(H2,75,92)(H,77,105)(H,78,112)(H,79,107)(H,80,94)(H,81,93)(H,82,95)(H,83,104)(H,84,108)(H,85,106)(H,86,109)(H,87,113)(H,88,111)(H,89,110)(H,96,97)(H,98,99)(H,100,101)(H,102,103)/t35-,36-,37-,43+,44+,45-,46+,47+,48+,49+,50-,60+,61+/m1/s1

0 references

InChIKey ^Béarla

DOAKLVKFURWEDJ-QCMAZARJSA-N

1 reference

UNII ^Béarla

15 Feabhra 2018

2 references

ChEBI ^Béarla

ChEBI ID ^Béarla

600103

daptomycin (Béarla)

5 Deireadh Fómhair 2016

UNII ^Béarla

NWQ5N31VKK

15 Feabhra 2018

PubChem CID ^Béarla

21585658

0 references

UniChem compound ID ^Béarla

1075046

1 reference

UniChem ^Béarla

DSSTox substance ID ^Béarla

DTXSID1041009

1 reference

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard ^Béarla

DSSTOX compound identifier ^Béarla

DTXCID9021009

0 references

LiverTox ID ^Béarla

Daptomycin

0 references

EC number ^Béarla

600-389-2

1 reference

ECHA Substance Infocard database ^Béarla

ECHA Substance Infocard ID ^Béarla

100.116.065

29 Iúil 2019

(3S)-3-{[(2S)-4-amino-2-{[(2S)-2-(decanoylamino)-3-(1H-indol-3-yl)propanoyl]amino}-4-oxobutanoyl]amino}-4-{[(3S,6S,9R,15S,18R,21S,24S,30S,31R)-3-[2-(2-aminophenyl)-2-oxoethyl]-24-(3-aminopropyl)-15,21-bis(carboxymethyl)-6-[(1R)-2-carboxy-1-methylethyl]-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29-decaoxo-1-oxa-4,7,10,13,16,19,22,25,28-nonaazacyclohentriacontan-30-yl]amino}-4-oxobutanoic acid (Béarla)

quotation ^Béarla

CAS no.: 103060-53-3 (Béarla)

ECHA Substance Infocard ID ^Béarla

100.116.065

1 reference

ECHA Substance Infocard database ^Béarla

ECHA Substance Infocard ID ^Béarla

100.116.065

29 Iúil 2019

(3S)-3-{[(2S)-4-amino-2-{[(2S)-2-(decanoylamino)-3-(1H-indol-3-yl)propanoyl]amino}-4-oxobutanoyl]amino}-4-{[(3S,6S,9R,15S,18R,21S,24S,30S,31R)-3-[2-(2-aminophenyl)-2-oxoethyl]-24-(3-aminopropyl)-15,21-bis(carboxymethyl)-6-[(1R)-2-carboxy-1-methylethyl]-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29-decaoxo-1-oxa-4,7,10,13,16,19,22,25,28-nonaazacyclohentriacontan-30-yl]amino}-4-oxobutanoic acid (Béarla)

quotation ^Béarla

CAS no.: 103060-53-3 (Béarla)

ATC code ^Béarla

J01XX09

1 reference

DrugBank ^Béarla

DrugBank ID ^Béarla

00080