ATRX chromatin remodeler (Q21105313)

Zinc finger, RING/FYVE/PHD-type

1 reference

P-loop containing nucleoside triphosphate hydrolase

1 reference

SNF2-like, N-terminal domain superfamily

1 reference

Helicase superfamily 1/2, ATP-binding domain, protein family

1 reference

Helicase, C-terminal domain, protein family

1 reference

1 reference

ADD domain, protein family

1 reference

2 references

13 November 2019

17 September 2016

2 references

13 November 2019

30 June 2016

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

chromo shadow domain binding

1 reference

8 April 2019

The mammalian heterochromatin protein 1 binds diverse nuclear proteins through a common motif that targets the chromoshadow domain

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

8 April 2019

ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

8 April 2019

Distinct factors control histone variant H3.3 localization at specific genomic regions

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

The ATRX syndrome protein forms a chromatin-remodeling complex with Daxx and localizes in promyelocytic leukemia nuclear bodies

DNA translocase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

methylated histone binding

IDA

1 reference

8 April 2019

The ATRX-ADD domain binds to H3 tail peptides and reads the combined methylation state of K4 and K9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

Mutations in a putative global transcriptional regulator cause X-linked mental retardation with alpha-thalassemia (ATR-X syndrome)

IDA

DNA helicase activity

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46100&geneProductId=UniProtKB:P46100

10 references

8 April 2019

ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

8 April 2019

ATRX binds to atypical chromatin domains at the 3' exons of zinc finger genes to preserve H3K9me3 enrichment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

8 April 2019

EBV tegument protein BNRF1 disrupts DAXX-ATRX to activate viral early gene transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

8 April 2019

ATRX directs binding of PRC2 to Xist RNA and Polycomb targets

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

8 April 2019

Cell cycle-dependent phosphorylation of the ATRX protein correlates with changes in nuclear matrix and chromatin association

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

8 April 2019

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

8 April 2019

ATRX dysfunction induces replication defects in primary mouse cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

8 April 2019

Interaction between chromatin proteins MECP2 and ATRX is disrupted by mutations that cause inherited mental retardation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

8 April 2019

Loss of ATRX Suppresses Resolution of Telomere Cohesion to Control Recombination in ALT Cancer Cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

8 April 2019

The ATRX syndrome protein forms a chromatin-remodeling complex with Daxx and localizes in promyelocytic leukemia nuclear bodies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

2 references

DNA-binding transcription factor activity, RNA polymerase II-specific

1 reference

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

SWI/SNF superfamily-type complex

cell component

1 reference

27 March 2018

The ATRX syndrome protein forms a chromatin-remodeling complex with Daxx and localizes in promyelocytic leukemia nuclear bodies

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46100&geneProductId=UniProtKB:P46100

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

3 references

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

1 reference

8 April 2019

Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

1 reference

8 April 2019

Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

1 reference

27 March 2018

Mutations in a putative global transcriptional regulator cause X-linked mental retardation with alpha-thalassemia (ATR-X syndrome)

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46100&geneProductId=UniProtKB:P46100

post-embryonic forelimb morphogenesis

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

multicellular organism growth

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

Sertoli cell development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

transcription, DNA-templated

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46100&geneProductId=UniProtKB:P46100

cellular response to DNA damage stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

positive regulation of telomeric RNA transcription from RNA pol II promoter

1 reference

8 April 2019

Genetic Inactivation of ATRX Leads to a Decrease in the Amount of Telomeric Cohesin and Level of Telomere Transcription in Human Glioma Cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

1 reference

8 April 2019

Mutations in ATRX, encoding a SWI/SNF-like protein, cause diverse changes in the pattern of DNA methylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

seminiferous tubule development

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric

1 reference

8 April 2019

Loss of ATRX Suppresses Resolution of Telomere Cohesion to Control Recombination in ALT Cancer Cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

IMP

forebrain development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

1 reference

27 March 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46100&geneProductId=UniProtKB:P46100

regulation of histone H3-K9 trimethylation

1 reference

8 April 2019

ATRX binds to atypical chromatin domains at the 3' exons of zinc finger genes to preserve H3K9me3 enrichment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

meiotic spindle organization

IMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

chromosome organization involved in meiotic cell cycle

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

chromatin organization

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

regulation of transcription, DNA-templated

1 reference

8 April 2019

Mutations in a putative global transcriptional regulator cause X-linked mental retardation with alpha-thalassemia (ATR-X syndrome)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46100

TAS

Identifiers

MeSH descriptor ID

D000075924

subject named as

X-linked Nuclear Protein

0 references

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

30 June 2016

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

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1 reference

1 reference

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1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

inferred by common MeSH mappings on source and on Wikidata

1 reference