Caspase 9 (Q4216687)

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mammalian protein found in Homo sapiens
  • CASP9
  • caspase 9, apoptosis-related cysteine peptidase
  • apoptotic protease activating factor 3
  • protein phosphatase 1, regulatory subunit 56
  • APAF-3
  • ICE-like apoptotic protease 6
  • ICE-LAP6
  • caspase-9
  • Apoptotic protease-activating factor 3
  • apoptotic protease MCH-6
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Language Label Description Also known as
English
Caspase 9
mammalian protein found in Homo sapiens
  • CASP9
  • caspase 9, apoptosis-related cysteine peptidase
  • apoptotic protease activating factor 3
  • protein phosphatase 1, regulatory subunit 56
  • APAF-3
  • ICE-like apoptotic protease 6
  • ICE-LAP6
  • caspase-9
  • Apoptotic protease-activating factor 3
  • apoptotic protease MCH-6

Statements

molecular function
protein binding
determination method
IPI
28 references
retrieved
8 April 2019
stated in
The structure of the BIR3 domain of cIAP1 in complex with the N-terminal peptides of SMAC and caspase-9
GOA
curator
UniProt
UniProt protein ID
P55211
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55211
determination method
IPI
retrieved
8 April 2019
stated in
CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis
GOA
curator
UniProt
UniProt protein ID
P55211
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55211
determination method
IPI
retrieved
8 April 2019
stated in
Characterization of a novel proapoptotic caspase-2- and caspase-9-binding protein
GOA
curator
UniProt
UniProt protein ID
P55211
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55211
determination method
IPI
retrieved
8 April 2019
stated in
c-Abl tyrosine kinase regulates caspase-9 autocleavage in the apoptotic response to DNA damage
GOA
curator
UniProt
UniProt protein ID
P55211
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55211
determination method
IPI
retrieved
8 April 2019
stated in
Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin
GOA
curator
UniProt
UniProt protein ID
P55211
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55211
determination method
IPI
retrieved
8 April 2019
stated in
HIP1R interacts with a member of Bcl-2 family, BCL2L10, and induces BAK-dependent cell death
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55211
determination method
IPI
retrieved
8 April 2019
stated in
Executioner caspase-3 and caspase-7 are functionally distinct proteases
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55211
determination method
IPI
retrieved
8 April 2019
stated in
An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55211
determination method
IPI
retrieved
8 April 2019
stated in
Mechanism of XIAP-mediated inhibition of caspase-9
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55211
determination method
IPI
retrieved
8 April 2019
stated in
Towards a proteome-scale map of the human protein–protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55211
determination method
IPI
retrieved
8 April 2019
stated in
IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55211
determination method
IPI
retrieved
8 April 2019
stated in
The dependence receptor DCC requires lipid raft localization for cell death signaling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55211
determination method
IPI
retrieved
8 April 2019
stated in
ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55211
determination method
IPI
retrieved
8 April 2019
stated in
The structure of the BIR3 domain of cIAP1 in complex with the N-terminal peptides of SMAC and caspase-9
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55211
determination method
IPI
retrieved
8 April 2019
stated in
Netrin-1 up-regulation in inflammatory bowel diseases is required for colorectal cancer progression
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55211
determination method
IPI
retrieved
8 April 2019
stated in
Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55211
determination method
IPI
retrieved
8 April 2019
stated in
The Apaf-1*procaspase-9 apoptosome complex functions as a proteolytic-based molecular timer
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55211
determination method
IPI
retrieved
8 April 2019
stated in
Integrin-linked kinase interacts with caspase-9 and -8 in an adhesion-dependent manner for promoting radiation-induced apoptosis in human leukemia cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55211
determination method
IPI
retrieved
8 April 2019
stated in
Structure of an apoptosome-procaspase-9 CARD complex.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55211
determination method
IPI
retrieved
8 April 2019
stated in
Livin, a novel inhibitor of apoptosis protein family member
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55211
determination method
IPI
retrieved
8 April 2019
stated in
LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55211
determination method
IPI
retrieved
8 April 2019
stated in
Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55211
determination method
IPI
retrieved
8 April 2019
stated in
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55211
determination method
IPI
retrieved
8 April 2019
stated in
SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP)
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55211
determination method
IPI
retrieved
8 April 2019
stated in
The holo-apoptosome: activation of procaspase-9 and interactions with caspase-3
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55211
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55211
determination method
IPI
retrieved
8 April 2019
stated in
Toward an understanding of the protein interaction network of the human liver
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55211
determination method
IPI
retrieved
8 April 2019
stated in
Pooled-matrix protein interaction screens using Barcode Fusion Genetics
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55211
determination method
IPI
cell component
biological process
Gene Atlas image
PBB GE CASP9 203984 s at fs.png
732 × 530; 11 KB
0 references

Identifiers

KBpedia ID
Caspase9
1 reference
stated in
KBpedia
retrieved
9 July 2020
 
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