Moesin (Q3860053)

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mammalian protein found in Homo sapiens
  • epididymis luminal protein 70
  • membrane-organizing extension spike protein
  • MSN
  • moesin
edit
Language Label Description Also known as
English
Moesin
mammalian protein found in Homo sapiens
  • epididymis luminal protein 70
  • membrane-organizing extension spike protein
  • MSN
  • moesin

Statements

molecular function
protein binding
determination method
IPI
21 references
retrieved
9 May 2019
stated in
The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho
GOA
curator
UniProt
UniProt protein ID
P26038
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038
determination method
IPI
retrieved
9 May 2019
stated in
Podoplanin binds ERM proteins to activate RhoA and promote epithelial-mesenchymal transition.
GOA
curator
UniProt
UniProt protein ID
P26038
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038
determination method
IPI
retrieved
9 May 2019
stated in
Ezrin has properties to self-associate at the plasma membrane
GOA
curator
UniProt
UniProt protein ID
P26038
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038
determination method
IPI
retrieved
9 May 2019
stated in
TIMAP is a positive regulator of pulmonary endothelial barrier function
GOA
curator
UniProt
UniProt protein ID
P26038
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038
determination method
IPI
retrieved
9 May 2019
stated in
The ERM proteins interact with the HOPS complex to regulate the maturation of endosomes
GOA
curator
UniProt
UniProt protein ID
P26038
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038
determination method
IPI
retrieved
9 May 2019
stated in
The Nck-interacting kinase phosphorylates ERM proteins for formation of lamellipodium by growth factors
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038
determination method
IPI
retrieved
9 May 2019
stated in
The EBP50-moesin interaction involves a binding site regulated by direct masking on the FERM domain
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038
determination method
IPI
retrieved
9 May 2019
stated in
Role of moesin in hyaluronan induced cell migration in glioblastoma multiforme
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038
determination method
IPI
retrieved
9 May 2019
stated in
Structural model of the dimeric Parkinson's protein LRRK2 reveals a compact architecture involving distant interdomain contacts
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038
determination method
IPI
retrieved
9 May 2019
stated in
14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038
determination method
IPI
retrieved
9 May 2019
stated in
GTPase activity and neuronal toxicity of Parkinson's disease-associated LRRK2 is regulated by ArfGAP1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038
determination method
IPI
retrieved
9 May 2019
stated in
Parkinson-related LRRK2 mutation R1441C/G/H impairs PKA phosphorylation of LRRK2 and disrupts its interaction with 14-3-3
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038
determination method
IPI
retrieved
9 May 2019
stated in
NHE-RF, a regulatory cofactor for Na(+)-H+ exchange, is a common interactor for merlin and ERM (MERM) proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038
determination method
IPI
retrieved
9 May 2019
stated in
LRRK2 kinase activity and biology are not uniformly predicted by its autophosphorylation and cellular phosphorylation site status
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038
determination method
IPI
retrieved
9 May 2019
stated in
Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038
determination method
IPI
retrieved
9 May 2019
stated in
Biochemical characterization of highly purified leucine-rich repeat kinases 1 and 2 demonstrates formation of homodimers
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038
determination method
IPI
retrieved
9 May 2019
stated in
LRRK2 kinase activity regulates synaptic vesicle trafficking and neurotransmitter release through modulation of LRRK2 macro-molecular complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038
determination method
IPI
retrieved
9 May 2019
stated in
GTPase activity regulates kinase activity and cellular phenotypes of Parkinson's disease-associated LRRK2
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038
determination method
IPI
retrieved
9 May 2019
stated in
A Parkinson's disease gene regulatory network identifies the signaling protein RGS2 as a modulator of LRRK2 activity and neuronal toxicity
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038
determination method
IPI
retrieved
9 May 2019
stated in
The Parkinson disease-linked LRRK2 protein mutation I2020T stabilizes an active state conformation leading to increased kinase activity
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038
determination method
IPI
retrieved
9 May 2019
stated in
Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038
determination method
IPI
cell component
extracellular exosome
determination method
IDA
6 references
retrieved
17 October 2017
stated in
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine
GOA
curator
UniProt
UniProt protein ID
P26038
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P26038&geneProductId=UniProtKB:P26038
determination method
IDA
retrieved
17 October 2017
stated in
Protein profile of exosomes from trabecular meshwork cells
GOA
curator
UniProt
UniProt protein ID
P26038
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P26038&geneProductId=UniProtKB:P26038
determination method
IDA
retrieved
17 October 2017
stated in
Large-scale proteomics and phosphoproteomics of urinary exosomes
GOA
curator
UniProt
UniProt protein ID
P26038
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P26038&geneProductId=UniProtKB:P26038
determination method
IDA
retrieved
17 October 2017
stated in
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis
GOA
curator
UniProt
UniProt protein ID
P26038
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P26038&geneProductId=UniProtKB:P26038
determination method
IDA
retrieved
17 October 2017
stated in
Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation
GOA
curator
UniProt
UniProt protein ID
P26038
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P26038&geneProductId=UniProtKB:P26038
determination method
IDA
retrieved
17 October 2017
stated in
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)
GOA
curator
UniProt
UniProt protein ID
P26038
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P26038&geneProductId=UniProtKB:P26038
determination method
IDA
extracellular exosome
determination method
HDA
6 references
retrieved
9 May 2019
stated in
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis
GOA
curator
UniProt
UniProt protein ID
P26038
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038
determination method
HDA
retrieved
9 May 2019
stated in
Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation
GOA
curator
UniProt
UniProt protein ID
P26038
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038
determination method
HDA
retrieved
9 May 2019
stated in
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)
GOA
curator
UniProt
UniProt protein ID
P26038
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038
determination method
HDA
retrieved
9 May 2019
stated in
Protein profile of exosomes from trabecular meshwork cells
GOA
curator
UniProt
UniProt protein ID
P26038
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038
determination method
HDA
retrieved
9 May 2019
stated in
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine
GOA
curator
UniProt
UniProt protein ID
P26038
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038
determination method
HDA
retrieved
9 May 2019
stated in
Large-scale proteomics and phosphoproteomics of urinary exosomes
GOA
curator
UniProt
UniProt protein ID
P26038
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038
determination method
HDA
biological process
Gene Atlas image
PBB GE MSN 200600 at fs.png
732 × 530; 11 KB
0 references

Identifiers

 
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