Replication and protection of telomeres (Q36854279)

16 August 2017

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title

Replication and protection of telomeres (English)

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16 August 2017

Ramiro E Verdun

1

1 reference

PubMed ID

17581575

16 August 2017

Jan Karlseder

series ordinal

2

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PubMed ID

17581575

16 August 2017

language of work or name

English

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publication date

1 June 2007

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16 August 2017

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16 August 2017

447

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16 August 2017

7147

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16 August 2017

924-931

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https://scigraph.springernature.com/pub.10.1038/nature05976

16 August 2017

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cites work

Variability at the telomeres of the human X/Y pseudoautosomal region

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

Coordinate regulation of G- and C strand length during new telomere synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

Mammalian telomeres end in a large duplex loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

T-loops and the origin of telomeres

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Telomere proteins: specific recognition and protection of the natural termini of Oxytricha macronuclear DNA

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Telomeric DNA-protein interactions of Oxytricha macronuclear DNA.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Cloning and expression of genes for the Oxytricha telomere-binding protein: specific subunit interactions in the telomeric complex

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Crystal structure of the Oxytricha nova telomere end binding protein complexed with single strand DNA

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Shelterin: the protein complex that shapes and safeguards human telomeres

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Control of telomere length by the human telomeric protein TRF1

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

TRF2 Protects Human Telomeres from End-to-End Fusions

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Control of human telomere length by TRF1 and TRF2

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Targeted deletion reveals an essential function for the telomere length regulator Trf1.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Origin of Concatemeric T7DNA

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

The serial cultivation of human diploid cell strains

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

A mutant with a defect in telomere elongation leads to senescence in yeast

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Extension of life-span by introduction of telomerase into normal human cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

TLC1: template RNA component of Saccharomyces cerevisiae telomerase

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Reverse transcriptase motifs in the catalytic subunit of telomerase

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Telomeres shorten during ageing of human fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Hayflick, his limit, and cellular ageing.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Protection of mammalian telomeres

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Loss of a yeast telomere: arrest, recovery, and chromosome loss.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Different telomere damage signaling pathways in human and mouse cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Senescence Induced by Altered Telomere State, Not Telomere Loss

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

DNA damage foci at dysfunctional telomeres

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

A DNA damage checkpoint response in telomere-initiated senescence

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

For better or worse? Telomerase inhibition and cancer

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Transformation of normal human cells in the absence of telomerase activation.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

A critical role for telomeres in suppressing and facilitating carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Alternative lengthening of telomeres: dangerous road less travelled

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Telomere maintenance by recombination in human cells.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Molecular characterization of inter-telomere and intra-telomere mutations in human ALT cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Absence of cancer-associated changes in human fibroblasts immortalized with telomerase

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Cellular senescence in aging primates.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Long lifespan in worms with long telomeric DNA.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Uncoupling of longevity and telomere length in C. elegans

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Telomere length homeostasis is achieved via a switch between telomerase- extendible and -nonextendible states.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Telomere length homeostasis requires that telomerase levels are limiting

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Essential role of mouse telomerase in highly proliferative organs

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

The telomerase reverse transcriptase is limiting and necessary for telomerase function in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Cdc13 delivers separate complexes to the telomere for end protection and replication

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Delivery of yeast telomerase to a DNA break depends on the recruitment functions of Cdc13 and Est1

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Cdc13 both positively and negatively regulates telomere replication

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Pol12, the B subunit of DNA polymerase alpha, functions in both telomere capping and length regulation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Alterations of DNA and chromatin structures at telomeres and genetic instability in mouse cells defective in DNA polymerase alpha

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Telomere structure and function

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Semi-conservative DNA replication through telomeres requires Taz1

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Defective telomere lagging strand synthesis in cells lacking WRN helicase activity.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Essential role of limiting telomeres in the pathogenesis of Werner syndrome

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

G-overhang dynamics at Tetrahymena telomeres

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Evidence for a new step in telomere maintenance

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Cell cycle-regulated generation of single-stranded G-rich DNA in the absence of telomerase

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Human telomeres have different overhang sizes at leading versus lagging strands

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Generation of Telomeric G Strand Overhangs Involves Both G and C Strand Cleavage

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Telomere-end processing the terminal nucleotides of human chromosomes

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

POT1 protects telomeres from a transient DNA damage response and determines how human chromosomes end

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Genetic regulation of telomere-telomere fusions in the yeast Saccharomyces cerevisae

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

DNA ligase IV-dependent NHEJ of deprotected mammalian telomeres in G1 and G2

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Cell cycle-dependent regulation of yeast telomerase by Ku.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Ku: a multifunctional protein involved in telomere maintenance

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

The Saccharomyces CDC13 protein is a single-strand TG1-3 telomeric DNA-binding protein in vitro that affects telomere behavior in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Ten1 functions in telomere end protection and length regulation in association with Stn1 and Cdc13

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Quantitative amplification of single-stranded DNA (QAOS) demonstrates that cdc13-1 mutants generate ssDNA in a telomere to centromere direction

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Regulation of telomere length and function by a Myb-domain protein in fission yeast

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Pot1, the putative telomere end-binding protein in fission yeast and humans

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

POT1 as a terminal transducer of TRF1 telomere length control

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Human POT1 facilitates telomere elongation by telomerase

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Homologous recombination generates T-loop-sized deletions at human telomeres

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Telomere maintenance is dependent on activities required for end repair of double-strand breaks.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

The role of the Mre11-Rad50-Xrs2 complex in telomerase- mediated lengthening of Saccharomyces cerevisiae telomeres

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Late S phase-specific recruitment of Mre11 complex triggers hierarchical assembly of telomere replication proteins in Saccharomyces cerevisiae.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Reciprocal association of the budding yeast ATM-related proteins Tel1 and Mec1 with telomeres in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Altering telomere structure allows telomerase to act in yeast lacking ATM kinases

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Telomerase and ATM/Tel1p protect telomeres from nonhomologous end joining

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Functional human telomeres are recognized as DNA damage in G2 of the cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

The DNA damage machinery and homologous recombination pathway act consecutively to protect human telomeres

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Telomeric DNA in ALT cells is characterized by free telomeric circles and heterogeneous t-loops

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Frequent recombination in telomeric DNA may extend the proliferative life of telomerase-negative cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Break-induced replication and recombinational telomere elongation in yeast

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Telomere maintenance without telomerase

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

The Mre11 complex is required for ATM activation and the G2/M checkpoint

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Partners and pathwaysrepairing a double-strand break.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05976

7 January 2021

Identifiers

DOI

10.1038/NATURE05976

1 reference

16 August 2017

1 reference

PubMed ID

17581575