Aromatic diamidines as antiparasitic agents (Q36210897)

12 August 2017

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title

Aromatic diamidines as antiparasitic agents (English)

1 reference

12 August 2017

Soeiro MN

1

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12 August 2017

De Souza EM

series ordinal

2

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12 August 2017

Stephens CE

series ordinal

3

1 reference

12 August 2017

Boykin DW

series ordinal

4

1 reference

12 August 2017

language of work or name

English

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publication date

1 August 2005

1 reference

Expert Opinion on Investigational Drugs

12 August 2017

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12 August 2017

14

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12 August 2017

8

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12 August 2017

957-972

1 reference

Highly active anti-Pneumocystis carinii compounds in a library of novel piperazine-linked bisbenzamidines and related compounds

12 August 2017

1 reference

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Apoptotic death in Leishmania donovani promastigotes in response to respiratory chain inhibition: complex II inhibition results in increased pentamidine cytotoxicity.

21 January 2018

1 reference

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Successful Treatment of Balamuthia Amoebic Encephalitis: Presentation of 2 Cases

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.14.8.957

Pentamidine is active in vitro against Fusarium species

21 January 2018

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Efficacy of Trypan: a diminazene based drug as antileishmanial agent

21 January 2018

1 reference

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Visceral leishmaniasis unresponsive to antimonial drugs. II. Response to high dosage sodium stibogluconate or prolonged treatment with pentamidine

21 January 2018

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Activity of pentamidine and pentamidine analogs against Toxoplasma gondii in cell cultures

21 January 2018

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Uptake and mode of action of drugs used against sleeping sickness.

21 January 2018

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Present status of chemotherapy and chemopropylaxis of human trypanosomiasis in the Eastern Hemisphere

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.14.8.957

Persistently culture positive acanthamoeba keratitis: in vivo resistance and in vitro sensitivity

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.14.8.957

Amoebicidal efficiencies of various diamidines against two strains of Acanthamoeba polyphaga

21 January 2018

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Chemotherapy of Babesia microti infections in Mongolian Jirds

21 January 2018

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Inhibition of Cryptosporidium parvum in neonatal Hsd:(ICR)BR Swiss miceby polyether ionophores and aromatic amidines

21 January 2018

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Structure-activity studies of dicationically substituted bis-benzimidazoles against Giardia lamblia: correlation of antigiardial activity with DNA binding affinity and giardial topoisomerase II inhibition

21 January 2018

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DB75, a novel trypanocidal agent, disrupts mitochondrial function in Saccharomyces cerevisiae

21 January 2018

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Pentamidine inhibition of group I intron splicing in Candida albicans correlates with growth inhibition

21 January 2018

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In vitro activities of pentamidine, pyrimethamine, trimethoprim, and sulfonamides against Aspergillus species

21 January 2018

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In vitro synergistic interaction between amphotericin B and pentamidine against Scedosporium prolificans.

21 January 2018

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Dicationic diarylfurans as anti-Pneumocystis carinii agents

21 January 2018

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The pulmonary effects of long-term exposure to aerosol pentamidine: a 5-year surveillance study in HIV-infected patients.

21 January 2018

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Fatal pancreatitis as a complication of therapy for HIV infection

21 January 2018

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Pentamidine-induced long QT syndrome and block of hERG trafficking

21 January 2018

1 reference

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Outcome of acanthamoeba keratitis treated with polyhexamethyl biguanide and propamidine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.8.957

The pathogenicity of diminazene aceturate-resistant Trypanosoma brucei in rats after treatment with the drug.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.8.957

Prodrugs for amidines: synthesis and anti-Pneumocystis carinii activity of carbamates of 2,5-bis(4-amidinophenyl)furan

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.8.957

Treatment perspectives for human African trypanosomiasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.8.957

Synthesis and antiprotozoal activity of aza-analogues of furamidine

21 January 2018

1 reference

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O-alkoxyamidine prodrugs of furamidine: in vitro transport and microsomal metabolism as indicators of in vivo efficacy in a mouse model of Trypanosoma brucei rhodesiense infection

21 January 2018

1 reference

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Novel dicationic imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines as antiprotozoal agents

21 January 2018

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The story of CGP 40 215: studies on its efficacy and pharmacokinetics in African green monkey infected with Trypanosoma brucei rhodesiense

21 January 2018

1 reference

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2,5-bis[4-(N-alkylamidino)phenyl]furans as anti-Pneumocystis carinii agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.8.957

Strong binding in the DNA minor groove by an aromatic diamidine with a shape that does not match the curvature of the groove

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.8.957

Modification of kinetoplast DNA minicircle composition in pentamidine-resistant Leishmania.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.8.957

Pentamidine is an uncoupler of oxidative phosphorylation in rat liver mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.8.957

Selective cleavage of kinetoplast DNA minicircles promoted by antitrypanosomal drugs

21 January 2018

1 reference

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A trypanosome oligopeptidase as a target for the trypanocidal agents pentamidine, diminazene and suramin

21 January 2018

1 reference

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Effects of exogenous polyamine and trypanocides on the DNA polymerase activities from Trypanosoma brucei brucei, mouse thymus and murine leukemia virus

21 January 2018

1 reference

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Selective inhibition of topoisomerases from Pneumocystis carinii compared with that of topoisomerases from mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.8.957

Pentamidine uptake and resistance in pathogenic protozoa: past, present and future

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.8.957

Drug transport and drug resistance in African trypanosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.8.957

The biochemical basis of arsenical-diamidine crossresistance in African trypanosomes

21 January 2018

1 reference

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Pentamidine uptake in Leishmania donovani and Leishmania amazonensis promastigotes and axenic amastigotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.8.957

Uptake of diamidine drugs by the P2 nucleoside transporter in melarsen-sensitive and -resistant Trypanosoma brucei brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.8.957

Characterisation of pentamidine-resistant Trypanosoma brucei brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.8.957

A drug resistance determinant in Trypanosoma brucei.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.8.957

Mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.8.957

Characterisation of melarsen-resistant Trypanosoma brucei brucei with respect to cross-resistance to other drugs and trypanothione metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.8.957

Resistance to pentamidine in Leishmania mexicana involves exclusion of the drug from the mitochondrion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.8.957

Characterization of the choline carrier of Plasmodium falciparum: a route for the selective delivery of novel antimalarial drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.8.957

Parasitic adaptive mechanisms in infection by leishmania

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.8.957

Proteinase inhibitors as antileishmanial agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.8.957

Leishmaniasis: drugs in the clinic, resistance and new developments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.8.957

Human leishmaniasis: clinical, diagnostic, and chemotherapeutic developments in the last 10 years

21 January 2018

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Natural products and synthetic compounds as immunomodulators

21 January 2018

1 reference

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The activity of diguanidino and 'reversed' diamidino 2,5-diarylfurans versus Trypanosoma cruzi and Leishmania donovani

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.8.957

Long-term exposure of Trypanosoma brucei gambiense to pentamidine in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.8.957

Trypanocidal activity of conformationally restricted pentamidine congeners

21 January 2018

1 reference

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Bisguanidine, bis(2-aminoimidazoline), and polyamine derivatives as potent and selective chemotherapeutic agents against Trypanosoma brucei rhodesiense. Synthesis and in vitro evaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.8.957

Distribution and quantitation of the anti-trypanosomal diamidine 2,5-bis(4-amidinophenyl)furan (DB75) and its N-methoxy prodrug DB289 in murine brain tissue

21 January 2018

1 reference

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Parasitology: the dawn of a new millennium.

21 January 2018

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A critical review on Chagas disease chemotherapy

21 January 2018

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Chemotherapy of Chagas disease

21 January 2018

1 reference

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Synthesis, anti-Trypanosoma cruzi activity and micelle interaction studies of bisguanylhydrazones analogous to pentamidine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.8.957

Malaria chemoprophylaxis: when should we use it and what are the options?

21 January 2018

1 reference

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Combined action of inhibitors of S-adenosylmethionine decarboxylase with an antimalarial drug, chloroquine, on Plasmodium falciparum

21 January 2018

1 reference

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Synthesis and antiprotozoal activity of 2,5-bis(4-guanylphenyl)thiophenes and -pyrroles

21 January 2018

1 reference

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Synthesis and antitrypanosomal activity of some bis(4-guanylphenyl) five- and six-membered ring heterocycles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.8.957

Parallel solution-phase synthesis of conformationally restricted congeners of pentamidine and evaluation of their antiplasmodial activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.8.957

Pentamidine for the treatment of Pneumocystis carinii pneumonia and other protozoal diseases

21 January 2018

1 reference

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Aerosolized pentamidine: effect on diagnosis and presentation of Pneumocystis carinii pneumonia

21 January 2018

1 reference

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Diagnosis of Pneumocystis carinii pneumonia by multiple lobe, site-directed bronchoalveolar lavage with immunofluorescent monoclonal antibody staining in human immunodeficiency virus-infected patients receiving aerosolized pentamidine chemoprophylax

21 January 2018

1 reference

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Effect of aerosolized pentamidine prophylaxis on the clinical severity and diagnosis of Pneumocystis carinii pneumonia

21 January 2018

1 reference

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The effect of nebulised pentamidine on the concentration of intra-oral Candida albicans in HIV-infected patients

21 January 2018

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Novel pentamidine analogs in the treatment of experimental Pneumocystis carinii pneumonia

21 January 2018

1 reference

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Trypanocidal activity of dicationic compounds related to pentamidine

21 January 2018

1 reference

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Activity of cationically substituted bis-benzimidazoles against experimental Pneumocystis carinii pneumonia

21 January 2018

1 reference

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N,N'-bis[4-(N-alkylamidino)phenyl]homopiperazines as anti-Pneumocystis carinii agents

21 January 2018

1 reference

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Novel bisbenzamidines as potential drug candidates for the treatment of Pneumocystis carinii pneumonia

21 January 2018

1 reference

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2,4-Diphenyl furan diamidines as novel anti-Pneumocystis carinii pneumonia agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.8.957

Diguanidino and "reversed" diamidino 2,5-diarylfurans as antimicrobial agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.8.957

Activity of pentamidine-loaded poly (D,L-lactide) nanoparticles against Leishmania infantum in a murine model

21 January 2018

1 reference

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In vitro study of leishmanicidal agents with drug carriers

21 January 2018

1 reference

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Therapy of human African trypanosomiasis: current situation

21 January 2018

1 reference

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10.1517/13543784.14.8.957

21 January 2018

Identifiers

DOI

1 reference

12 August 2017

1 reference