Pentamidine uptake and resistance in pathogenic protozoa: past, present and future (Q35134470)

6 August 2017

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title

Pentamidine uptake and resistance in pathogenic protozoa: past, present and future (English)

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6 August 2017

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2

Michael P Barrett

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Harry P de Koning

object named as

Harry P de Koning

4

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Steve Ward

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ORCID Public Data File 2021

author name string

Patrick G Bray

1

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PubMed ID

12763430

6 August 2017

Michael P Barrett

2

1 reference

PubMed ID

12763430

6 August 2017

Stephen A Ward

3

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6 August 2017

1 May 2003

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6 August 2017

Trends in Parasitology

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6 August 2017

19

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6 August 2017

5

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6 August 2017

232-239

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6 August 2017

Studies in Chemotherapy

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7 January 2021

Treatment of Sleeping Sickness in Sierra Leone

1 reference

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7 January 2021

Pentamidine isethionate. A review of its antiprotozoal activity, pharmacokinetic properties and therapeutic use in Pneumocystis carinii pneumonia

1 reference

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7 January 2021

Pentamidine Transport and Sensitivity inbrucei-Group Trypanosomes*

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7 January 2021

Pentamidine transport in Trypanosoma brucei—Kinetics and specificity

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7 January 2021

Selective cleavage of kinetoplast DNA minicircles promoted by antitrypanosomal drugs

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7 January 2021

Uptake of diamidine drugs by the P2 nucleoside transporter in melarsen-sensitive and -resistant Trypanosoma brucei brucei

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7 January 2021

Arsenical-resistant trypanosomes lack an unusual adenosine transporter

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7 January 2021

A nucleoside transporter from Trypanosoma brucei involved in drug resistance.

1 reference

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7 January 2021

The biochemical basis of arsenical-diamidine crossresistance in African trypanosomes

1 reference

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7 January 2021

Uptake of pentamidine in Trypanosoma brucei brucei is mediated by the P2 adenosine transporter and at least one novel, unrelated transporter

1 reference

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7 January 2021

Characterization of a Nucleoside/Proton Symporter in ProcyclicTrypanosoma brucei brucei

1 reference

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7 January 2021

Transporters in African trypanosomes: role in drug action and resistance

1 reference

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7 January 2021

Characterisation of melarsen-resistant Trypanosoma brucei brucei with respect to cross-resistance to other drugs and trypanothione metabolism

1 reference

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7 January 2021

In vivo and in vitro sensitivity of Trypanosoma evansi and T. equiperdum to diminazene, suramin, MelCy, quinapyramine and isometamidium

1 reference

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7 January 2021

Susceptibility of Ugandan Trypanosoma brucei rhodesiense isolated from man and animal reservoirs to diminazene, isometamidium and melarsoprol

1 reference

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7 January 2021

Characterisation of pentamidine-resistant Trypanosoma brucei brucei

1 reference

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7 January 2021

Availability and affordability of treatment for Human African Trypanosomiasis

1 reference

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7 January 2021

Melarsoprol refractory T. b. gambiense from Omugo, north-western Uganda.

1 reference

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7 January 2021

The phenomenon of treatment failures in Human African Trypanosomiasis

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7 January 2021

Chemotherapy of leishmaniasis

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7 January 2021

Monitoring drug resistance in leishmaniasis

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7 January 2021

The efficacy of pentamidine combined with allopurinol and immunotherapy for the treatment of patients with diffuse cutaneous leishmaniasis

1 reference

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7 January 2021

Successful treatment of Colombian cutaneous leishmaniasis with four injections of pentamidine

1 reference

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7 January 2021

Kinetics and molecular characteristics of arginine transport by Leishmania donovani promastigotes

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7 January 2021

Putrescine uptake inhibition by aromatic diamidines in leishmania infantum promastigotes

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7 January 2021

Putrescine and spermidine transport in Leishmania.

1 reference

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7 January 2021

Resistance to pentamidine in Leishmania mexicana involves exclusion of the drug from the mitochondrion.

1 reference

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7 January 2021

Effects of pentamidine on polyamine level and biosynthesis in wild-type, pentamidine-treated, and pentamidine-resistant Leishmania

1 reference

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7 January 2021

Altered transport properties of pentamidine-resistant Leishmania donovani and L. amazonensis promastigotes

1 reference

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7 January 2021

Modification of kinetoplast DNA minicircle composition in pentamidine-resistant Leishmania.

1 reference

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7 January 2021

Phenotypic characterization of Leishmania mexicana pentamidine-resistant promastigotes. Modulation of the resistance during in-vitro developmental life cycle.

1 reference

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7 January 2021

In vitro life cycle of pentamidine-resistant amastigotes: stability of the chemoresistant phenotypes is dependent on the level of resistance induced

1 reference

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7 January 2021

Effect of pentamidine isethionate on the ultrastructure and morphology of Leishmania mexicana amazonensis in vitro

1 reference

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7 January 2021

The ultrastructural changes of Leishmania tropica after treatment with pentamidine

1 reference

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7 January 2021

Ca2+ transport by digitonin-permeabilized Leishmania donovani. Effects of Ca2+, pentamidine and WR-6026 on mitochondrial membrane potential in situ

1 reference

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7 January 2021

Characterization of the PNT1 pentamidine resistance gene of Saccharomyces cerevisiae

1 reference

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7 January 2021

Mutations affecting a yeast mitochondrial inner membrane protein, pnt1p, block export of a mitochondrially synthesized fusion protein from the matrix

1 reference

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7 January 2021

Pentamidine is an uncoupler of oxidative phosphorylation in rat liver mitochondria

1 reference

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7 January 2021

Modulation of mitochondrial electrical potential: a candidate mechanism for drug resistance in African trypanosomes

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7 January 2021

Observations on the Course ofPlasmodium KnowlesiInfection in Monkeys(Macacus Rhesus), with Notes on Its Treatment by (1) Atebrin and (2) 1: 11 Normal Undecane Diamidine, Together with a Note on the Action of the Latter on Bird Malaria

1 reference

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7 January 2021

The Course ofPlasmodium RelictumInfection in Canaries and the Treatment of Bird and Monkey Malaria with Synthetic Bases

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7 January 2021

Structure-activity relationships of analogs of pentamidine against Plasmodium falciparum and Leishmania mexicana amazonensis

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7 January 2021

Diamidine compounds: selective uptake and targeting in Plasmodium falciparum.

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7 January 2021

A voltage-dependent channel involved in nutrient uptake by red blood cells infected with the malaria parasite

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7 January 2021

Membrane transport in the malaria-infected erythrocyte

1 reference

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7 January 2021

Cellular uptake of chloroquine is dependent on binding to ferriprotoporphyrin IX and is independent of NHE activity in Plasmodium falciparum

1 reference

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7 January 2021

Hemoglobin metabolism in the malaria parasite Plasmodium falciparum

1 reference

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7 January 2021

Late results of treatment of sleeping sickness in Sierra Leone by antrypol tryparsamide pentamidine and propamidine singly and in various combinations

1 reference

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7 January 2021

The efficacy of certain trypanocidal compounds against Trypanosoma gambiense infection in man

1 reference

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7 January 2021

The efficacy of pentamidine in the treatment of early-late stage Trypanosoma brucei gambiense trypanosomiasis

1 reference

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7 January 2021

Treatment of human African trypanosomiasis--present situation and needs for research and development

1 reference

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7 January 2021

A field experiment on the prophylactic value of pentamidine in sleeping sickness.

1 reference

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7 January 2021

[Human african trypanosomiasis: A history of its therapies and their failures]

1 reference

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7 January 2021

10.1016/S1471-4922(03)00069-2

Identifiers

DOI

1 reference

6 August 2017

1 reference

PubMed ID

12763430