Major histocompatibility complex class II transactivator CIITA is a viral restriction factor that targets human T-cell lymphotropic virus type 1 Tax-1 function and inhibits viral replication. (Q35275030)

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English	Major histocompatibility complex class II transactivator CIITA is a viral restriction factor that targets human T-cell lymphotropic virus type 1 Tax-1 function and inhibits viral replication.	scientific article

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9 February 2020

Major histocompatibility complex class II transactivator CIITA is a viral restriction factor that targets human T-cell lymphotropic virus type 1 Tax-1 function and inhibits viral replication (English)

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9 February 2020

Human T-lymphotropic virus 1

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9 February 2020

Roberto S. Accolla

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Giovanna Tosi

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9 February 2020

Vibeke Andresen

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9 February 2020

Marco Turci

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9 February 2020

Umberto Bertazzoni

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9 February 2020

Genoveffa Franchini

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9 February 2020

Guido Poli

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3 August 2011

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9 February 2020

Journal of Virology

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9 February 2020

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9 February 2020

10719-10729

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9 February 2020

TRIM22 inhibits HIV-1 transcription independently of its E3 ubiquitin ligase activity, Tat, and NF-kappaB-responsive long terminal repeat elements

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12 July 2018

The dual function of the MHC class II transactivator CIITA against HTLV retroviruses.

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12 July 2018

TRIM family proteins and their emerging roles in innate immunity

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12 July 2018

The HTLV-1 Tax interactome

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12 July 2018

The APOBEC3 cytidine deaminases: an innate defensive network opposing exogenous retroviruses and endogenous retroelements

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12 July 2018

Human T-cell leukaemia virus type 1 (HTLV-1) infectivity and cellular transformation

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12 July 2018

Inhibition of human T cell leukemia virus type 2 replication by the suppressive action of class II transactivator and nuclear factor Y.

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12 July 2018

Comparative biology of human T-cell lymphotropic virus type 1 (HTLV-1) and HTLV-2

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12 July 2018

Deregulation of cell-signaling pathways in HTLV-1 infection

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12 July 2018

Emergence of unique primate T-lymphotropic viruses among central African bushmeat hunters

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Discovery of a new human T-cell lymphotropic virus (HTLV-3) in Central Africa

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12 July 2018

The epidemiology and disease outcomes of human T-lymphotropic virus type II.

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12 July 2018

HTLV-1 and associated adult T-cell leukemia/lymphoma.

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12 July 2018

The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys

1 reference

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12 July 2018

Enhancement of CIITA transcriptional function by ubiquitin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187506

12 July 2018

The MHC class II transcriptional activator (CIITA) inhibits HTLV-2 viral replication by blocking the function of the viral transactivator Tax-2.

1 reference

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12 July 2018

Tax recruitment of CBP/p300, via the KIX domain, reveals a potent requirement for acetyltransferase activity that is chromatin dependent and histone tail independent

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12 July 2018

Phosphorylation of CIITA directs its oligomerization, accumulation and increased activity on MHCII promoters

1 reference

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12 July 2018

Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein

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12 July 2018

Human T-cell leukemia virus type 1 Tax protein binds to assembled nuclear proteasomes and enhances their proteolytic activity

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12 July 2018

The MHC class II transactivator: prey and hunter in infectious diseases

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12 July 2018

A 36-amino-acid region of CIITA is an effective inhibitor of CBP: novel mechanism of gamma interferon-mediated suppression of collagen alpha(2)(I) and other promoters

1 reference

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12 July 2018

Self-association of class II transactivator correlates with its intracellular localization and transactivation

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12 July 2018

Acetylation by PCAF enhances CIITA nuclear accumulation and transactivation of major histocompatibility complex class II genes

1 reference

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12 July 2018

MHC class II transactivator inhibits IL-4 gene transcription by competing with NF-AT to bind the coactivator CREB binding protein (CBP)/p300.

1 reference

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12 July 2018

Associations and interactions between bare lymphocyte syndrome factors

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12 July 2018

CIITA is a transcriptional coactivator that is recruited to MHC class II promoters by multiple synergistic interactions with an enhanceosome complex

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12 July 2018

The class II transactivator CIITA is a transcriptional integrator

1 reference

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12 July 2018

PCAF interacts with tax and stimulates tax transactivation in a histone acetyltransferase-independent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187506

12 July 2018

The coactivator CBP stimulates human T-cell lymphotrophic virus type I Tax transactivation in vitro

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12 July 2018

Involvement of CREB binding protein in expression of major histocompatibility complex class II genes via interaction with the class II transactivator

1 reference

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12 July 2018

An exposed KID-like domain in human T-cell lymphotropic virus type 1 Tax is responsible for the recruitment of coactivators CBP/p300

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187506

12 July 2018

Human T cell leukemia virus type I (HTLV-I) and human diseases

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12 July 2018

Physical and functional interaction between the human T-cell lymphotropic virus type 1 Tax1 protein and the CCAAT binding protein NF-Y

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Human T-cell lymphotropic virus type II-associated myelopathy: clinical and immunologic profiles

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12 July 2018

Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)

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Construction and characterization of infectious human T-cell leukemia virus type 1 molecular clones.

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12 July 2018

The amino terminus of Tax is required for interaction with the cyclic AMP response element binding protein

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12 July 2018

Molecular mechanisms of human T-cell leukemia/lymphotropic virus type I infection

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12 July 2018

A new subtype of human T-cell leukemia virus (HTLV-II) associated with a T-cell variant of hairy cell leukemia

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Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease

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Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma

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12 July 2018

aIr-1, a newly found locus on mouse chromosome 16 encoding a trans-acting activator factor for MHC class II gene expression

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Cis-acting sequences responsible for the transcriptional activation of human T-cell leukemia virus type I constitute a conditional enhancer

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Transformation to continuous growth of primary human T lymphocytes by human T-cell leukemia virus type I X-region genes transduced by a Herpesvirus saimiri vector

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Identification of HTLV-I tax trans-activator mutants exhibiting novel transcriptional phenotypes

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Human T-cell leukemia virus type I infection of monocytes and microglial cells in primary human cultures

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12 July 2018

MHC class II enhanceosome: how is the class II transactivator recruited to DNA-bound activators?

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26 September 2018

Mechanisms of nuclear import and export that control the subcellular localization of class II transactivator

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p300 and p300/cAMP-responsive element-binding protein associated factor interact with human T-cell lymphotropic virus type-1 Tax in a multi-histone acetyltransferase/activator-enhancer complex

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Control of cAMP-regulated enhancers by the viral transactivator Tax through CREB and the co-activator CBP.

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26 September 2018

The HLA class II transcriptional activator blocks the function of HIV-1 Tat and inhibits viral replication

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813598

12 December 2020

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10.1128/JVI.00813-11

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9 February 2020

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9 February 2020

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9 February 2020

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