Human T-cell leukaemia virus type 1 (HTLV-1) infectivity and cellular transformation (Q36769835)

16 August 2017

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title

Human T-cell leukaemia virus type 1 (HTLV-1) infectivity and cellular transformation (English)

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Human T-lymphotropic virus 1

16 August 2017

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Masao Matsuoka

1

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author name string

Kuan-Teh Jeang

series ordinal

2

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PubMed ID

17384582

16 August 2017

language of work or name

English

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publication date

1 April 2007

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16 August 2017

Nature Reviews Cancer

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16 August 2017

7

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16 August 2017

4

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16 August 2017

270-280

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https://scigraph.springernature.com/pub.10.1038/nrc2111

16 August 2017

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cites work

Dating the origin of the African human T-cell lymphotropic virus type-i (HTLV-I) subtypes

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Enhancement of LFA-1-mediated T cell adhesion by human T lymphotropic virus type 1 p12I1.

21 January 2018

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Human T-cell leukemia virus type 1 Tax and cell cycle progression: role of cyclin D-cdk and p110Rb

21 January 2018

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Discovery of adult T-cell leukemia

21 January 2018

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The discovery of the first human retrovirus: HTLV-1 and HTLV-2

31 March 2020

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Discovery of HTLV-1, the first human retrovirus, its unique regulatory mechanisms, and insights into pathogenesis

31 March 2020

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Molecular mechanisms of cellular transformation by HTLV-1 Tax.

31 March 2020

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Emergence of unique primate T-lymphotropic viruses among central African bushmeat hunters

31 March 2020

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Discovery of a new human T-cell lymphotropic virus (HTLV-3) in Central Africa

31 March 2020

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Global epidemiology of HTLV-I infection and associated diseases

31 March 2020

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Evaluation of adult T-cell leukemia/lymphoma incidence and its impact on non-Hodgkin lymphoma incidence in southwestern Japan.

31 March 2020

1 reference

Cellular immune response to HTLV-1.

31 March 2020

1 reference

Human T-cell leukemia virus type I (HTLV-I) infection and the onset of adult T-cell leukemia (ATL)

31 March 2020

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Concurrence of lymphoma type adult T-cell leukemia in three sisters

31 March 2020

1 reference

Rapid quantification of HTLV-I provirus load: detection of monoclonal proliferation of HTLV-I-infected cells among blood donors.

31 March 2020

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Expression of FoxP3, a key molecule in CD4CD25 regulatory T cells, in adult T-cell leukaemia/lymphoma cells

31 March 2020

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Regulatory T cell-like activity of Foxp3+ adult T cell leukemia cells.

31 March 2020

1 reference

Human T-cell leukemia virus type 1 Tax protein down-regulates pre-T-cell receptor alpha gene transcription in human immature thymocytes

31 March 2020

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Thymus-derived leukemia-lymphoma in mice transgenic for the Tax gene of human T-lymphotropic virus type I.

31 March 2020

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Spread of HTLV-I between lymphocytes by virus-induced polarization of the cytoskeleton

31 March 2020

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Engagement of specific T-cell surface molecules regulates cytoskeletal polarization in HTLV-1-infected lymphocytes.

31 March 2020

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Human T-lymphotropic virus, type 1, tax protein triggers microtubule reorientation in the virological synapse

31 March 2020

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Induction of ICAM-1 and LFA-3 by Tax1 of human T-cell leukemia virus type 1 and mechanism of down-regulation of ICAM-1 or LFA-1 in adult-T-cell-leukemia cell lines

31 March 2020

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Preferential selection of human T-cell leukemia virus type I provirus integration sites in leukemic versus carrier states

31 March 2020

1 reference

Persistent oligoclonal expansion of human T-cell leukemia virus type 1-infected circulating cells in patients with Tropical spastic paraparesis/HTLV-1 associated myelopathy

31 March 2020

1 reference

Zidovudine plus lamivudine in Human T-Lymphotropic Virus type-I-associated myelopathy: a randomised trial

31 March 2020

1 reference

De novo human T-cell leukemia virus type 1 infection of human lymphocytes in NOD-SCID, common gamma-chain knockout mice

31 March 2020

1 reference

The ubiquitous glucose transporter GLUT-1 is a receptor for HTLV

31 March 2020

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GLUT1 is not the primary binding receptor but is associated with cell-to-cell transmission of human T-cell leukemia virus type 1.

31 March 2020

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Impaired production of naive T lymphocytes in human T-cell leukemia virus type I-infected individuals: its implications in the immunodeficient state

31 March 2020

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Human T-cell lymphotropic virus type 1 open reading frame II-encoded p30II is required for in vivo replication: evidence of in vivo reversion

31 March 2020

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Human T-cell leukemia virus type 1 expressing nonoverlapping tax and rex genes replicates and immortalizes primary human T lymphocytes but fails to replicate and persist in vivo

31 March 2020

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Human T-lymphotropic virus type 1 mitochondrion-localizing protein p13(II) is required for viral infectivity in vivo.

31 March 2020

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Endoplasmic reticulum and cis-Golgi localization of human T-lymphotropic virus type 1 p12(I): association with calreticulin and calnexin

31 March 2020

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Free major histocompatibility complex class I heavy chain is preferentially targeted for degradation by human T-cell leukemia/lymphotropic virus type 1 p12(I) protein

31 March 2020

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HTLV-1-encoded p30II is a post-transcriptional negative regulator of viral replication

31 March 2020

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Human T-lymphotropic virus type 1 p30(II) functions as a transcription factor and differentially modulates CREB-responsive promoters

31 March 2020

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Existence of escape mutant in HTLV-I tax during the development of adult T-cell leukemia

31 March 2020

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Genetic and epigenetic inactivation of tax gene in adult T-cell leukemia cells

31 March 2020

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5'-long terminal repeat-selective CpG methylation of latent human T-cell leukemia virus type 1 provirus in vitro and in vivo

31 March 2020

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Silencing of human T-cell leukemia virus type I gene transcription by epigenetic mechanisms

31 March 2020

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Mechanisms of genomic instability in human cancer: insights from studies with human papillomavirus oncoproteins

31 March 2020

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Two discrete events, human T-cell leukemia virus type I Tax oncoprotein expression and a separate stress stimulus, are required for induction of apoptosis in T-cells

31 March 2020

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Activation of the anaphase promoting complex by HTLV-1 tax leads to senescence

31 March 2020

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Human T-cell leukemia virus type I at age 25: a progress report

31 March 2020

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The activation of Akt/PKB signaling pathway and cell survival.

31 March 2020

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PI-3K and Akt are mediators of AP-1 induction by 5-MCDE in mouse epidermal Cl41 cells

31 March 2020

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Activated AKT regulates NF-kappaB activation, p53 inhibition and cell survival in HTLV-1-transformed cells

31 March 2020

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Role for Akt/protein kinase B and activator protein-1 in cellular proliferation induced by the human T-cell leukemia virus type 1 tax oncoprotein

31 March 2020

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Longitudinal inhibition of PI3K/Akt/mTOR signaling by LY294002 and rapamycin induces growth arrest of adult T-cell leukemia cells.

31 March 2020

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Activation of NF-kappaB by HTLV-I and implications for cell transformation

31 March 2020

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Segregation of NF-kappaB activation through NEMO/IKKgamma by Tax and TNFalpha: implications for stimulus-specific interruption of oncogenic signaling

31 March 2020

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Retroviral oncoprotein Tax induces processing of NF-kappaB2/p100 in T cells: evidence for the involvement of IKKalpha

31 March 2020

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Elevated expression of CD30 in adult T-cell leukemia cell lines: possible role in constitutive NF-kappaB activation

31 March 2020

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Tax-independent constitutive IkappaB kinase activation in adult T-cell leukemia cells

31 March 2020

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Molecular mechanism of cell cycle progression induced by the oncogene product Tax of human T-cell leukemia virus type I.

31 March 2020

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Physical interaction of human T-cell leukemia virus type 1 Tax with cyclin-dependent kinase 4 stimulates the phosphorylation of retinoblastoma protein

31 March 2020

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The HTLV-1 Tax protein binding domain of cyclin-dependent kinase 4 (CDK4) includes the regulatory PSTAIRE helix

31 March 2020

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The HTLV-I Tax oncoprotein targets the retinoblastoma protein for proteasomal degradation

31 March 2020

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Activation of E2F-mediated transcription by human T-cell leukemia virus type I Tax protein in a p16(INK4A)-negative T-cell line

31 March 2020

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Down-regulation of the INK4 family of cyclin-dependent kinase inhibitors by tax protein of HTLV-1 through two distinct mechanisms

31 March 2020

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The human T cell leukemia/lymphotropic virus type 1 Tax protein represses MyoD-dependent transcription by inhibiting MyoD-binding to the KIX domain of p300. A potential mechanism for Tax-mediated repression of the transcriptional activity of basic h

31 March 2020

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The role of cyclin D2 and p21/waf1 in human T-cell leukemia virus type 1 infected cells

31 March 2020

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Binding of human virus oncoproteins to hDlg/SAP97, a mammalian homolog of the Drosophila discs large tumor suppressor protein

31 March 2020

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Tax oncoprotein of HTLV-1 binds to the human homologue of Drosophila discs large tumor suppressor protein, hDLG, and perturbs its function in cell growth control

31 March 2020

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The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions

31 March 2020

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Binding of APC to the human homolog of the Drosophila discs large tumor suppressor protein.

31 March 2020

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The APC-hDLG complex negatively regulates cell cycle progression from the G0/G1 to S phase

31 March 2020

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PDZ domain-binding motif of human T-cell leukemia virus type 1 Tax oncoprotein augments the transforming activity in a rat fibroblast cell line

31 March 2020

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Inactivation of tumor suppressor Dlg1 augments transformation of a T-cell line induced by human T-cell leukemia virus type 1 Tax protein

31 March 2020

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Human T-cell leukemia virus type 2 (HTLV-2) Tax protein transforms a rat fibroblast cell line but less efficiently than HTLV-1 Tax.

31 March 2020

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Aneuploidy theory explains tumor formation, the absence of immune surveillance, and the failure of chemotherapy

31 March 2020

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Prevalent loss of mitotic spindle checkpoint in adult T-cell leukemia confers resistance to microtubule inhibitors

31 March 2020

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Centrosome aberrations: cause or consequence of cancer progression?

31 March 2020

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Centrosomal aberrations in primary invasive breast cancer are associated with nodal status and hormone receptor expression

31 March 2020

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Centrosome amplification and the origin of chromosomal instability in breast cancer

31 March 2020

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Involvement of Crm1 in hepatitis B virus X protein-induced aberrant centriole replication and abnormal mitotic spindles

31 March 2020

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The retroviral oncoprotein Tax targets the coiled-coil centrosomal protein TAX1BP2 to induce centrosome overduplication

31 March 2020

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Abnormal centrosome amplification in cells through the targeting of Ran-binding protein-1 by the human T cell leukemia virus type-1 Tax oncoprotein

31 March 2020

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Centrosome amplification in adult T-cell leukemia and human T-cell leukemia virus type 1 Tax-induced human T cells

31 March 2020

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DNA aneuploidy of adult T-cell leukemia cells

31 March 2020

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The spindle checkpoint: structural insights into dynamic signalling

31 March 2020

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Heterozygous deletion of mitotic arrest-deficient protein 1 (MAD1) increases the incidence of tumors in mice

31 March 2020

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MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells

31 March 2020

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Human T cell leukemia virus type 1 oncoprotein Tax targets the human mitotic checkpoint protein MAD1

31 March 2020

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Characterization of regions in hsMAD1 needed for binding hsMAD2. A polymorphic change in an hsMAD1 leucine zipper affects MAD1-MAD2 interaction and spindle checkpoint function

31 March 2020

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Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461)

31 March 2020

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HTLV-I Tax directly binds the Cdc20-associated anaphase-promoting complex and activates it ahead of schedule

31 March 2020

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Epstein-barr virus-induced resistance to drugs that activate the mitotic spindle assembly checkpoint in Burkitt's lymphoma cells

31 March 2020

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c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability

31 March 2020

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Human T-cell leukemia virus type 1 Tax interacts with Chk1 and attenuates DNA-damage induced G2 arrest mediated by Chk1.

31 March 2020

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The HTLV-1 tax oncoprotein attenuates DNA damage induced G1 arrest and enhances apoptosis in p53 null cells

31 March 2020

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HTLV-I trans-activator protein, tax, is a trans-repressor of the human beta-polymerase gene

31 March 2020

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Defective DNA repair in cells with human T-cell leukemia/bovine leukemia viruses: role of tax gene

31 March 2020

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p53-independent induction of apoptosis by the HTLV-I tax protein following UV irradiation

31 March 2020

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Reduced expression of human mismatch repair genes in adult T-cell leukemia

31 March 2020

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Increased expression of telomere length regulating factors TRF1, TRF2 and TIN2 in patients with adult T-cell leukemia

31 March 2020

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Inactivation of hTERT transcription by Tax.

31 March 2020

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Clastogenic effect of the human T-cell leukemia virus type I Tax oncoprotein correlates with unstabilized DNA breaks

31 March 2020

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Ku protein as a potential human T-cell leukemia virus type 1 (HTLV-1) Tax target in clastogenic chromosomal instability of mammalian cells

31 March 2020

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A truncated human chromosome 16 associated with α thalassaemia is stabilized by addition of telomeric repeat (TTAGGG)n

31 March 2020

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Recognition of a chromosome truncation site associated with α-thalassaemia by human telomerase

31 March 2020

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Telomerase activity and telomere length as prognostic factors of adult T-cell leukemia

31 March 2020

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Correlation of telomerase activity with development and progression of adult T-cell leukemia.

31 March 2020

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Functional inactivation of p53 by human T-cell leukemia virus type 1 Tax protein: mechanisms and clinical implications

31 March 2020

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Inactivation of p53 by human T-cell lymphotropic virus type 1 Tax requires activation of the NF-kappaB pathway and is dependent on p53 phosphorylation.

31 March 2020

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HTLV-1 tax oncoprotein represses the p53-mediated trans-activation function through coactivator CBP sequestration

31 March 2020

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Evidence for NF-kappaB- and CBP-independent repression of p53's transcriptional activity by human T-cell leukemia virus type 1 Tax in mouse embryo and primary human fibroblasts

31 March 2020

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The complementary strand of the human T-cell leukemia virus type 1 RNA genome encodes a bZIP transcription factor that down-regulates viral transcription

31 March 2020

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Human T-cell leukemia virus minus strand transcription in infected T-cells

31 March 2020

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The HBZ factor of human T-cell leukemia virus type I dimerizes with transcription factors JunB and c-Jun and modulates their transcriptional activity

31 March 2020

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HBZ, a new important player in the mystery of adult T-cell leukemia

31 March 2020

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HBZ interacts with JunD and stimulates its transcriptional activity

31 March 2020

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HTLV-I antisense transcripts initiating in the 3'LTR are alternatively spliced and polyadenylated

31 March 2020

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Involvement of IL-2/IL-2R system activation by parasite antigen in polyclonal expansion of CD4(+)25(+) HTLV-1-infected T-cells in human carriers of both HTLV-1 and S. stercoralis

31 March 2020

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HTLV-I basic leucine zipper factor gene mRNA supports proliferation of adult T cell leukemia cells

31 March 2020

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Ancient origin and molecular features of the novel human T-lymphotropic virus type 3 revealed by complete genome analysis.

31 March 2020

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Enhancement of infectivity and persistence in vivo by HBZ, a natural antisense coded protein of HTLV-1.

31 March 2020

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Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

31 March 2020

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A new G-CSF-supported combination chemotherapy, LSG15, for adult T-cell leukaemia-lymphoma: Japan Clinical Oncology Group Study 9303.

31 March 2020

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Proteasome inhibitor, bortezomib, potently inhibits the growth of adult T-cell leukemia cells both in vivo and in vitro.

31 March 2020

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Dual targeting of transformed and untransformed HTLV-1-infected T cells by DHMEQ, a potent and selective inhibitor of NF-kappaB, as a strategy for chemoprevention and therapy of adult T-cell leukemia

31 March 2020

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Targeting the Akt/mammalian target of rapamycin pathway for radiosensitization of breast cancer.

31 March 2020

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Potent and selective inhibitors of Akt kinases slow the progress of tumors in vivo

31 March 2020

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Improved outcome of adult T cell leukemia/lymphoma with allogeneic hematopoietic stem cell transplantation

31 March 2020

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Allogeneic stem-cell transplantation with reduced conditioning intensity as a novel immunotherapy and antiviral therapy for adult T-cell leukemia/lymphoma

31 March 2020

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Graft-versus-Tax response in adult T-cell leukemia patients after hematopoietic stem cell transplantation.

31 March 2020

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Modulation of nuclear factor-kappaB by human T cell leukemia virus type 1 Tax protein: implications for oncogenesis and inflammation

31 March 2020

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Human T-cell leukemia virus infection of human hematopoietic progenitor cells: maintenance of virus infection during differentiation in vitro and in vivo

31 March 2020

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7 January 2021

Differential transactivation of the intercellular adhesion molecule 1 gene promoter by Tax1 and Tax2 of human T-cell leukemia viruses.

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7 January 2021

Transcriptional activation of the vascular cell adhesion molecule-1 gene in T lymphocytes expressing human T-cell leukemia virus type 1 Tax protein.

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7 January 2021

Stimulation of cyclin-dependent kinase activity and G1- to S-phase transition in human lymphocytes by the human T-cell leukemia/lymphotropic virus type 1 Tax protein.

1 reference

7 January 2021

Human T-cell leukemia virus type 1 Tax releases cell cycle arrest induced by p16INK4a

1 reference

7 January 2021

Identifiers

DOI

10.1038/NRC2111

1 reference

PubMed ID

17384582

Dimensions Publication ID

16 August 2017

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1 reference

PubMed ID

17384582