TRF2 functions as a protein hub and regulates telomere maintenance by recognizing specific peptide motifs (Q33418271)

26 July 2017

TRF2 functions as a protein hub and regulates telomere maintenance by recognizing specific peptide motifs (English)

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Protein phosphatase 1, regulatory subunit 10

26 July 2017

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GOA release 2020-03-11

Liuh-Yow Chen

4

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author name string

Hyeung Kim

1

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26 July 2017

Ok-Hee Lee

2

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26 July 2017

Huawei Xin

3

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26 July 2017

Jun Qin

5

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26 July 2017

Heekyung Kate Chae

6

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26 July 2017

Shiaw-Yih Lin

7

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26 July 2017

Amin Safari

8

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26 July 2017

Dan Liu

9

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26 July 2017

Zhou Songyang

10

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26 July 2017

language of work or name

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15 March 2009

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Nature Structural & Molecular Biology

26 July 2017

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26 July 2017

16

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26 July 2017

4

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26 July 2017

372-379

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https://scigraph.springernature.com/pub.10.1038/nsmb.1575

26 July 2017

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cites work

Inside the mammalian telomere interactome: regulation and regulatory activities of telomeres

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Switching and signaling at the telomere

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Balancing instability: dual roles for telomerase and telomere dysfunction in tumorigenesis

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Telomerase in cancer and aging

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Telomerase in the human organism

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Mammalian telomeres and telomerase: why they matter for cancer and aging

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Beginning to understand the end of the chromosome

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Telomeric DNA oligonucleotides form novel intramolecular structures containing guanine-guanine base pairs

31 March 2020

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Shelterin: the protein complex that shapes and safeguards human telomeres

31 March 2020

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Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2

31 March 2020

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Telomeric localization of TRF2, a novel human telobox protein

31 March 2020

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Replication and protection of telomeres

31 March 2020

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Importance of TRF1 for Functional Telomere Structure

31 March 2020

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DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion

31 March 2020

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DNA damage foci at dysfunctional telomeres

31 March 2020

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Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1.

31 March 2020

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Homologous recombination generates T-loop-sized deletions at human telomeres

31 March 2020

1 reference

TRF2 Protects Human Telomeres from End-to-End Fusions

31 March 2020

1 reference

Apollo, an Artemis-related nuclease, interacts with TRF2 and protects human telomeres in S phase

31 March 2020

1 reference

The Apollo 5' exonuclease functions together with TRF2 to protect telomeres from DNA repair

31 March 2020

1 reference

A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins

31 March 2020

1 reference

SH2 domains recognize specific phosphopeptide sequences

31 March 2020

1 reference

Recognition and regulation of primary-sequence motifs by signaling modular domains

31 March 2020

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A motif-based profile scanning approach for genome-wide prediction of signaling pathways

31 March 2020

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A DNA damage checkpoint response in telomere-initiated senescence

31 March 2020

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p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

31 March 2020

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Telosome, a mammalian telomere-associated complex formed by multiple telomeric proteins

31 March 2020

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The human Rap1 protein complex and modulation of telomere length

31 March 2020

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Simultaneous visualization of multiple protein interactions in living cells using multicolor fluorescence complementation analysis

31 March 2020

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Telomere maintenance through spatial control of telomeric proteins

31 March 2020

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Isolation and characterization of PNUTS, a putative protein phosphatase 1 nuclear targeting subunit

31 March 2020

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BRIT1/MCPH1 is a DNA damage responsive protein that regulates the Brca1-Chk1 pathway, implicating checkpoint dysfunction in microcephaly

31 March 2020

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BRIT1 regulates early DNA damage response, chromosomal integrity, and cancer

31 March 2020

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Regulation of mitotic entry by microcephalin and its overlap with ATR signalling

31 March 2020

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MCPH1 functions in an H2AX-dependent but MDC1-independent pathway in response to DNA damage

31 March 2020

1 reference

A critical role for TPP1 and TIN2 interaction in high-order telomeric complex assembly

31 March 2020

1 reference

TPP1 is a homologue of ciliate TEBP-beta and interacts with POT1 to recruit telomerase

31 March 2020

1 reference

A RAP1/TRF2 complex inhibits nonhomologous end-joining at human telomeric DNA ends

31 March 2020

1 reference

wRAPing up the end to prevent telomere fusions

31 March 2020

1 reference

Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response

31 March 2020

1 reference

PTOP interacts with POT1 and regulates its localization to telomeres

31 March 2020

1 reference

Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis

31 March 2020

1 reference

The use of peptide library for the determination of kinase peptide substrates.

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19287395

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NSMB.1575

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Dimensions Publication ID

26 July 2017

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