A direct intersection between p53 and transforming growth factor beta pathways targets chromatin modification and transcription repression of the alpha-fetoprotein gene (Q28507391)

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English	A direct intersection between p53 and transforming growth factor beta pathways targets chromatin modification and transcription repression of the alpha-fetoprotein gene	scientific journal article

Statements

scholarly article

1 reference

24 January 2017

A direct intersection between p53 and transforming growth factor beta pathways targets chromatin modification and transcription repression of the alpha-fetoprotein gene (English)

1 reference

24 January 2017

Transformation related protein 53

1 reference

GOA release 2020-03-11

SMAD family member 2

1 reference

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Transforming growth factor, beta 1

1 reference

GOA release 2020-03-11

SMAD family member 4

1 reference

GOA release 2020-03-11

Michelle Craig Barton

object named as

Michelle Craig Barton

7

0 references

author name string

Deepti S. Wilkinson

1

1 reference

24 January 2017

Stacey K. Ogden

2

1 reference

24 January 2017

Sabrina A. Stratton

3

1 reference

24 January 2017

Julie L. Piechan

4

1 reference

24 January 2017

Thi T. Nguyen

5

1 reference

24 January 2017

George A. Smulian

6

1 reference

24 January 2017

language of work or name

0 references

publication date

1 February 2005

1 reference

24 January 2017

Molecular and Cellular Biology

1 reference

24 January 2017

25

1 reference

24 January 2017

3

1 reference

24 January 2017

1200–1212

1 reference

24 January 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC544019/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Direct interaction of Ski with either Smad3 or Smad4 is necessary and sufficient for Ski-mediated repression of transforming growth factor-beta signaling

1 reference

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19 March 2017

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

1 reference

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19 March 2017

Repression of TGF-beta signaling by the oncogenic protein SKI in human melanomas: consequences for proliferation, survival, and metastasis

1 reference

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19 March 2017

Structural mechanism of Smad4 recognition by the nuclear oncoprotein Ski: insights on Ski-mediated repression of TGF-beta signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=544019

19 March 2017

Smad3 allostery links TGF-beta receptor kinase activation to transcriptional control

1 reference

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19 March 2017

Increased susceptibility to tumorigenesis of ski-deficient heterozygous mice

1 reference

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19 March 2017

Loss of the SKI proto-oncogene in individuals affected with 1p36 deletion syndrome is predicted by strain-dependent defects in Ski-/- mice

1 reference

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19 March 2017

Cytoplasmic localization of the oncogenic protein Ski in human cutaneous melanomas in vivo: functional implications for transforming growth factor beta signaling

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TGFbeta signaling in growth control, cancer, and heritable disorders

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Histone acetylation and an epigenetic code

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The sno gene, which encodes a component of the histone deacetylase complex, acts as a tumor suppressor in mice

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19 March 2017

c-Ski acts as a transcriptional co-repressor in transforming growth factor-beta signaling through interaction with smads

1 reference

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19 March 2017

Interaction of the Ski oncoprotein with Smad3 regulates TGF-beta signaling

1 reference

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19 March 2017

Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein

1 reference

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19 March 2017

The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signaling

1 reference

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19 March 2017

p53 in embryonic development: maintaining a fine balance

1 reference

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19 March 2017

Ski is a component of the histone deacetylase complex required for transcriptional repression by Mad and thyroid hormone receptor

1 reference

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Heterodimers of the SnoN and Ski oncoproteins form preferentially over homodimers and are more potent transforming agents

1 reference

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TGF-beta signal transduction

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Mice lacking the ski proto-oncogene have defects in neurulation, craniofacial, patterning, and skeletal muscle development

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p53, the cellular gatekeeper for growth and division

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HDA1 and HDA3 are components of a yeast histone deacetylase (HDA) complex

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Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

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Tissue-specific in vitro transcription from the mouse albumin promoter

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19 March 2017

Histone acetyltransferases

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7 April 2017

TGF-beta signaling in tumor suppression and cancer progression

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Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

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Transcriptional control by the TGF-beta/Smad signaling system

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p53: puzzle and paradigm

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Ski and SnoN: negative regulators of TGF-beta signaling

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29 September 2017

siRNA technology

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29 September 2017

p53-regulated transcriptional program associated with genotoxic stress-induced apoptosis

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Functional regulation of p73 and p63: development and cancer

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Defective T-cell activation is associated with augmented transforming growth factor Beta sensitivity in mice with mutations in the Sno gene

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29 September 2017

Signal-dependent N-CoR Requirement for Repression by the Ski Oncoprotein

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Multiple roles of the tumor suppressor p53.

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The evolution of diverse biological responses to DNA damage: insights from yeast and p53.

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Stress signals utilize multiple pathways to stabilize p53

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Smads as transcriptional co-modulators

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29 September 2017

Homeodomain and winged-helix transcription factors recruit activated Smads to distinct promoter elements via a common Smad interaction motif

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29 September 2017

Signaling inputs converge on nuclear effectors in TGF-beta signaling

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29 September 2017

Hepatocyte nuclear factor 3 relieves chromatin-mediated repression of the alpha-fetoprotein gene

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29 September 2017

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29 September 2017

Growth stimulation of murine fibroblasts by TGF-beta1 depends on the expression of a functional p53 protein

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29 September 2017

p53-mediated repression of alpha-fetoprotein gene expression by specific DNA binding

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Induction of p53 and Bax during TGF-beta 1 initiated apoptosis in rat liver epithelial cells

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Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members

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29 September 2017

pX, the HBV-encoded coactivator, interacts with components of the transcription machinery and stimulates transcription in a TAF-independent manner

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29 September 2017

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29 September 2017

Direct interaction of the hepatitis B virus HBx protein with p53 leads to inhibition by HBx of p53 response element-directed transactivation

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29 September 2017

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29 September 2017

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29 September 2017

p53 targets chromatin structure alteration to repress alpha-fetoprotein gene expression

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2 June 2018

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2 June 2018

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27 November 2018

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27 November 2018

Inhibition of hepatitis-B-virus core promoter by p53: implications for carcinogenesis in hepatocytes

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27 November 2018

A single erythroid-specific DNase I super-hypersensitive site activates high levels of human beta-globin gene expression in transgenic mice

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Hepatitis B viral transactivator HBx alleviates p53-mediated repression of alpha-fetoprotein gene expression

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12 December 2020

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Identifiers

10.1128/MCB.25.3.1200-1212.2005

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24 January 2017

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1 reference

24 January 2017

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