Integrin cytoplasmic domain-associated protein-1 attenuates sprouting angiogenesis (Q24338343)

Notch receptor 1

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Delta like canonical Notch ligand 4

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Endothelial cell specific molecule 1

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negative regulation of cell migration involved in sprouting angiogenesis

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1 reference

Hellmut G Augustin

8

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ORCID Public Data File 2021

author name string

René Brütsch

1

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Sven S Liebler

2

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Joycelyn Wüstehube

3

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Arne Bartol

4

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Stefanie E Herberich

5

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M Gordian Adam

6

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Anja Telzerow

7

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Andreas Fischer

Integrin Cytoplasmic domain-Associated Protein-1 (ICAP-1) promotes migration of myoblasts and affects focal adhesions

9

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language of work or name

English

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publication date

3 September 2010

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published in

Circulation Research

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volume

107

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issue

5

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page(s)

592-601

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cites work

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The forkhead transcription factors, Foxc1 and Foxc2, are required for arterial specification and lymphatic sprouting during vascular development

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Hypoxia-mediated activation of Dll4-Notch-Hey2 signaling in endothelial progenitor cells and adoption of arterial cell fate

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Endocan is a VEGF-A and PI3K regulated gene with increased expression in human renal cancer.

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Genetics of cavernous angiomas

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Proteomic identification of the cerebral cavernous malformation signaling complex

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Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia

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The cerebral cavernous malformation signaling pathway promotes vascular integrity via Rho GTPases

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Spheroid-based engineering of a human vasculature in mice.

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Spheroid-based human endothelial cell microvessel formation in vivo.

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Cerebral cavernous malformation protein CCM1 inhibits sprouting angiogenesis by activating DELTA-NOTCH signaling

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Analysis of gene expression in single live neurons

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Interaction of the integrin beta1 cytoplasmic domain with ICAP-1 protein

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Rho kinase inhibition rescues the endothelial cell cerebral cavernous malformation phenotype

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Disruption of focal adhesions by integrin cytoplasmic domain-associated protein-1 alpha

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ICAP-1, a novel beta1 integrin cytoplasmic domain-associated protein, binds to a conserved and functionally important NPXY sequence motif of beta1 integrin

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Integration of endothelial cells in multicellular spheroids prevents apoptosis and induces differentiation

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Cell adaptive response to extracellular matrix density is controlled by ICAP-1-dependent beta1-integrin affinity

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Cerebral cavernous malformations proteins inhibit Rho kinase to stabilize vascular integrity

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Nuclear translocation of integrin cytoplasmic domain-associated protein 1 stimulates cellular proliferation.

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Interaction between krit1 and icap1alpha infers perturbation of integrin beta1-mediated angiogenesis in the pathogenesis of cerebral cavernous malformation

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Regulation of vascular morphogenesis by Notch signaling

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Krit 1 interactions with microtubules and membranes are regulated by Rap1 and integrin cytoplasmic domain associated protein-1

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Recent insights into cerebral cavernous malformations: a complex jigsaw puzzle under construction

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Akt signaling: linking membrane events to life and death decisions

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Regulation of neuronal survival by the serine-threonine protein kinase Akt

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Notch activation induces endothelial cell cycle arrest and participates in contact inhibition: role of p21Cip1 repression

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Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function

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The BTB-Kelch protein KLEIP controls endothelial migration and sprouting angiogenesis.

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Notch1 is an effector of Akt and hypoxia in melanoma development

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Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade

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Transcriptional profiling of VEGF-A and VEGF-C target genes in lymphatic endothelium reveals endothelial-specific molecule-1 as a novel mediator of lymphangiogenesis

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Microarray analysis of retinal endothelial tip cells identifies CXCR4 as a mediator of tip cell morphology and branching

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Krit1 modulates beta 1-integrin-mediated endothelial cell proliferation

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Defective osteoblast function in ICAP-1-deficient mice

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Ccm1 is required for arterial morphogenesis: implications for the etiology of human cavernous malformations.

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