Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation (Q24296620)

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8 January 2020

title

Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation (English)

1 reference

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ubiquitin protein ligase binding

8 January 2020

main subject

1 reference

GOA release 2020-03-11

protein ubiquitination

1 reference

2

1 reference

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8 January 2020

Simone Engelender

9

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8 January 2020

10

Christopher A Ross

1 reference

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8 January 2020

author name string

Kah Leong Lim

1

1 reference

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8 January 2020

Jeanne M M Tan

3

1 reference

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8 January 2020

Cheng Wang

4

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8 January 2020

Kenny K K Chung

5

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8 January 2020

Yi Zhang

6

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8 January 2020

Yuji Tanaka

7

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8 January 2020

Wanli Smith

8

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8 January 2020

Valina L Dawson

11

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8 January 2020

Ted M Dawson

12

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8 January 2020

language of work or name

English

0 references

publication date

1 February 2005

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8 January 2020

published in

Journal of Neuroscience

1 reference

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8 January 2020

volume

25

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8 January 2020

issue

8

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8 January 2020

page(s)

2002-2009

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Immunohistochemical and subcellular localization of Parkin protein: absence of protein in autosomal recessive juvenile parkinsonism patients

8 January 2020

cites work

1 reference

12 December 2020

A role for ubiquitination in mitochondrial inheritance in Saccharomyces cerevisiae

1 reference

12 December 2020

Synphilin-1 is present in Lewy bodies in Parkinson's disease

1 reference

12 December 2020

New animal models for Parkinson's disease

1 reference

12 December 2020

Association between early-onset Parkinson's disease and mutations in the parkin gene

1 reference

12 December 2020

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

1 reference

12 December 2020

Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity

1 reference

12 December 2020

Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

1 reference

12 December 2020

Features of the parkin/ariadne-like ubiquitin ligase, HHARI, that regulate its interaction with the ubiquitin-conjugating enzyme, Ubch7

1 reference

12 December 2020

Mechanisms underlying ubiquitination

1 reference

12 December 2020

Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease

1 reference

12 December 2020

An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin

1 reference

12 December 2020

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

1 reference

12 December 2020

Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease

1 reference

12 December 2020

The role of the ubiquitin-proteasomal pathway in Parkinson's disease and other neurodegenerative disorders

1 reference

12 December 2020

Complex relationship between Parkin mutations and Parkinson disease

1 reference

12 December 2020

The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility

1 reference

12 December 2020

Synphilin-1 degradation by the ubiquitin-proteasome pathway and effects on cell survival

1 reference

12 December 2020

Update on Parkinson disease

1 reference

12 December 2020

Parkin binds to alpha/beta tubulin and increases their ubiquitination and degradation

1 reference

12 December 2020

Dorfin Localizes to Lewy Bodies and Ubiquitylates Synphilin-1

1 reference

12 December 2020

Identification and functional characterization of a novel R621C mutation in the synphilin-1 gene in Parkinson's disease

1 reference

12 December 2020

Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons

1 reference

12 December 2020

Siah-1 facilitates ubiquitination and degradation of synphilin-1

1 reference

12 December 2020

SEPT5_v2 is a parkin-binding protein

1 reference

12 December 2020

Molecular Pathways of Neurodegeneration in Parkinson's Disease

1 reference

12 December 2020

A missense mutation (L166P) in DJ-1, linked to familial Parkinson's disease, confers reduced protein stability and impairs homo-oligomerization.

1 reference

12 December 2020

Parkin genetics: one model for Parkinson's disease

1 reference

12 December 2020

Ubiquitylation of synphilin-1 and alpha-synuclein by SIAH and its presence in cellular inclusions and Lewy bodies imply a role in Parkinson's disease

1 reference

12 December 2020

S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function

1 reference

12 December 2020

Biomedicine. Parkinson's--divergent causes, convergent mechanisms.

1 reference

12 December 2020

Loss of locus coeruleus neurons and reduced startle in parkin null mice

1 reference

12 December 2020

Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity

1 reference

12 December 2020

A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein

1 reference

12 December 2020

A ubiquitin mutant with specific defects in DNA repair and multiubiquitination

1 reference

12 December 2020

Stress resistance in Saccharomyces cerevisiae is strongly correlated with assembly of a novel type of multiubiquitin chain

1 reference

12 December 2020

Familial juvenile parkinsonism: clinical and pathologic study in a family.

1 reference

12 December 2020

Ubiquitin lys63 is involved in ubiquitination of a yeast plasma membrane protein

1 reference

12 December 2020

10.1523/JNEUROSCI.4474-04.2005

Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

755084

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15728840%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

755084

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Consolidated OpenCitations Corpus – April 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15728840%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

2 references

Consolidated OpenCitations Corpus – April 2017

755084