Cholesterol suppresses cellular TGF-beta responsiveness: implications in atherogenesis (Q24294300)

Transforming growth factor beta receptor 2

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SMAD family member 2

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transforming growth factor beta 1

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response to cholesterol

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Transforming growth factor, beta receptor II

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Transforming growth factor, beta receptor I

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Transforming growth factor, beta 1

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author name string

Chun-Lin Chen

1

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I-Hua Liu

2

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Steven J Fliesler

3

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Xianlin Han

4

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Shuan Shian Huang

5

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Jung San Huang

Pleiotropic effects of statins

6

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language of work or name

English

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publication date

15 October 2007

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published in

Journal of Cell Science

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volume

120

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page(s)

3509-21

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issue

Pt 20

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cites work

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TGF-beta signal transduction

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Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

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Cellular growth inhibition by IGFBP-3 and TGF-beta1 requires LRP-1

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Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

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TGF-beta signaling in tumor suppression and cancer progression

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Ligand-dependent and -independent transforming growth factor-beta receptor recycling regulated by clathrin-mediated endocytosis and Rab11.

27 September 2017

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Dynamic redistribution of raft domains as an organizing platform for signaling during cell chemotaxis

27 September 2017

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Disruption of TGF-β signaling in T cells accelerates atherosclerosis

27 September 2017

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Cholesterol is important in control of EGF receptor kinase activity but EGF receptors are not concentrated in caveolae

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c-Src is required for glial cell line-derived neurotrophic factor (GDNF) family ligand-mediated neuronal survival via a phosphatidylinositol-3 kinase (PI-3K)-dependent pathway.

27 September 2017

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Acute cholesterol depletion inhibits clathrin-coated pit budding

27 September 2017

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Genomic instability in the type II TGF-beta1 receptor gene in atherosclerotic and restenotic vascular cells

27 September 2017

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Mechanism of TGFbeta receptor inhibition by FKBP12

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Transforming growth factor-beta and the protection from cardiovascular injury hypothesis.

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Transforming growth factor-beta-induced growth inhibition and cellular hypertrophy in cultured vascular smooth muscle cells

27 September 2017

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27 September 2017

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27 September 2017

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Transforming growth factor-beta is a strong and fast acting positive regulator of the level of type-1 plasminogen activator inhibitor mRNA in WI-38 human lung fibroblasts

27 September 2017

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Hyaluronan regulates transforming growth factor-beta1 receptor compartmentalization

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Mechanisms of TGF-beta-induced cell cycle arrest

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30 May 2018

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Transforming growth factor-beta inhibits E-selectin expression on human endothelial cells

30 May 2018

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ApoE-deficient mice are a model of lipoprotein oxidation in atherogenesis. Demonstration of oxidation-specific epitopes in lesions and high titers of autoantibodies to malondialdehyde-lysine in serum.

30 May 2018

1 reference

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Transforming growth factor-beta receptor type I-dependent fibrogenic gene program is mediated via activation of Smad1 and ERK1/2 pathways.

30 May 2018

1 reference

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Suppression of atherogenesis by delivery of TGFbeta1ACT using adeno-associated virus type 2 in LDLR knockout mice

29 November 2018

1 reference

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Cellular heparan sulfate negatively modulates transforming growth factor-beta1 (TGF-beta1) responsiveness in epithelial cells.

29 November 2018

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Genetic ablation of caveolin-1 confers protection against atherosclerosis

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1 reference

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1 reference

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1 reference

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Identifiers

DOI

10.1242/JCS.006916

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2526566

2526566

1 reference

1 reference

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