YES proto-oncogene 1, Src family tyrosine kinase (Q21097216)

From Wikidata

Jump to navigation Jump to search

mammalian protein found in Homo sapiens

proto-oncogene tyrosine-protein kinase YES
YES1 proto-oncogene, Src family tyrosine kinase
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
cellular yes-1 protein
Yamaguchi sarcoma oncogene
proto-oncogene c-Yes
tyrosine-protein kinase Yes
p61-Yes

Language	Label	Description	Also known as
English	YES proto-oncogene 1, Src family tyrosine kinase	mammalian protein found in Homo sapiens	proto-oncogene tyrosine-protein kinase YES YES1 proto-oncogene, Src family tyrosine kinase YES1 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 cellular yes-1 protein Yamaguchi sarcoma oncogene proto-oncogene c-Yes tyrosine-protein kinase Yes p61-Yes

Statements

1 reference

13 November 2019

UniProt protein ID

SH3-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07947

Protein kinase-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07947

SH2 domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07947

Src family kinases (SFKs) [cytosol]

0 references

Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

SH2 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Tyrosine-protein kinase Yes, SH3 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

SH3 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase, ATP binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Tyrosine-protein kinase, catalytic domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Tyrosine-protein kinase, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

transferase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

nucleotide binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

protein kinase activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

transmembrane transporter binding

determination method

1 reference

8 April 2019

Regulation of a transient receptor potential (TRP) channel by tyrosine phosphorylation. SRC family kinase-dependent tyrosine phosphorylation of TRPV4 on TYR-253 mediates its response to hypotonic stress

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

epidermal growth factor receptor binding

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

kinase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

protein binding

determination method

10 references

8 April 2019

Phosphotyrosine signaling networks in epidermal growth factor receptor overexpressing squamous carcinoma cells

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

8 April 2019

VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKC{delta}-driven migration

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

8 April 2019

The naturally processed CD95L elicits a c-yes/calcium/PI3K-driven cell migration pathway

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

8 April 2019

Phospho-tyrosine dependent protein-protein interaction network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

8 April 2019

Analysis of 5-lipoxygenase phosphorylation on molecular level by MALDI-MS

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

8 April 2019

Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

8 April 2019

EG-1 interacts with c-Src and activates its signaling pathway

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

8 April 2019

The SRC-associated protein CUB Domain-Containing Protein-1 regulates adhesion and motility

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

8 April 2019

Lyn, a Src family kinase, regulates activation of epidermal growth factor receptors in lung adenocarcinoma cells

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

determination method

1 reference

8 April 2019

The Lyn kinase C-lobe mediates Golgi export of Lyn through conformation-dependent ACSL3 association

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

protein tyrosine kinase activity

determination method

10 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

8 April 2019

Characterization of cDNA clones for the human c-yes gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

8 April 2019

Tyrosyl phosphorylation of Shp2 is required for normal ERK activation in response to some, but not all, growth factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

8 April 2019

Vav2 is required for cell spreading

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

8 April 2019

Gab2 is involved in differential phosphoinositide 3-kinase signaling by two splice forms of c-Kit

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

8 April 2019

Kit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

8 April 2019

Steel factor stimulates the tyrosine phosphorylation of the proto-oncogene product, p95vav, in human hemopoietic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

signaling receptor binding

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

determination method

2 references

phosphotyrosine residue binding

determination method

1 reference

8 April 2019

Tarp regulates early Chlamydia-induced host cell survival through interactions with the human adaptor protein SHC1

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

non-membrane spanning protein tyrosine kinase activity

determination method

3 references

8 April 2019

Cooperation between integrin alphavbeta3 and VEGFR2 in angiogenesis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

Golgi apparatus

determination method

1 reference

8 April 2019

The Lyn kinase C-lobe mediates Golgi export of Lyn through conformation-dependent ACSL3 association

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

determination method

1 reference

17 October 2017

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07947&geneProductId=UniProtKB:P07947

determination method

extrinsic component of cytoplasmic side of plasma membrane

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

plasma membrane

determination method

4 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

8 April 2019

The Lyn kinase C-lobe mediates Golgi export of Lyn through conformation-dependent ACSL3 association

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

microtubule organizing center

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

extracellular exosome

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

determination method

1 reference

8 April 2019

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

extracellular exosome

determination method

1 reference

8 April 2019

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

glutamatergic synapse

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

postsynaptic specialization, intracellular component

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

biological process

cellular response to transforming growth factor beta stimulus

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

cellular response to retinoic acid

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

cell differentiation

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

Fc-gamma receptor signaling pathway involved in phagocytosis

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

phosphorylation

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

transmembrane receptor protein tyrosine kinase signaling pathway

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

ephrin receptor signaling pathway

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

T cell costimulation

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

cellular response to platelet-derived growth factor stimulus

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

protein phosphorylation

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

regulation of vascular permeability

determination method

1 reference

8 April 2019

Cooperation between integrin alphavbeta3 and VEGFR2 in angiogenesis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

regulation of cell population proliferation

determination method

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07947&geneProductId=UniProtKB:P07947

determination method

positive regulation of peptidyl-tyrosine phosphorylation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

peptidyl-tyrosine autophosphorylation

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

protein autophosphorylation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

leukocyte migration

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

positive regulation of transcription by RNA polymerase II

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

innate immune response

determination method

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07947&geneProductId=UniProtKB:P07947

determination method

determination method

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07947&geneProductId=UniProtKB:P07947

determination method

regulation of glucose transmembrane transport

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947

determination method

physically interacts with

enzyme inhibitor

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

enzyme inhibitor

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

tyrosine-protein kinase, active site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07947

protein kinase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07947

protein kinase, ATP binding site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07947

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07947

tyrosine-protein kinase, catalytic domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07947

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07947

serine-threonine/tyrosine-protein kinase, catalytic domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07947

Tyrosine-protein kinase Yes, SH3 domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07947

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000324740

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000324740

ENSP00000462468

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000462468

ENSP00000464380

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000464380

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q21097216&oldid=2022912543"