plicamycin &#160; Turanci (Q3906700)

Hybrid compounds generated by the introduction of a nogalamycin-producing plasmid into Streptomyces argillaceus ^Turanci

ranar wallafa

17 Nuwamba 2015

DrugBank ID ^Turanci

06810

tsarin sinadaran

Mithramycin A.png
640 × 425; 50 KB

0 references

Taro

1,084.472653 dalton

1 reference

stated in ^Turanci

PubChem ^Turanci

PubChem CID ^Turanci

CHEMBL1237054 (Turanci)

retrieved ^Turanci

21 Satumba 2016

stereoisomer of ^Turanci

plicamycin ^Turanci

2 references

based on heuristic ^Turanci

inferred from InChIKey ^Turanci

based on heuristic ^Turanci

inferred from InChI ^Turanci

Deoliosyl-3C-|A-L-digitoxosyl-MTM ^Turanci

1 reference

based on heuristic ^Turanci

inferred from InChI ^Turanci

sinadaran dabara

C₅₂H₇₆O₂₄

1 reference

stated in ^Turanci

PubChem ^Turanci

PubChem CID ^Turanci

CHEMBL1237054 (Turanci)

retrieved ^Turanci

21 Satumba 2016

canonical SMILES ^Turanci

CC1C(C(CC(O1)OC2CC(OC(C2O)C)OC3=CC4=CC5=C(C(=O)C(C(C5)C(C(=O)C(C(C)O)O)OC)OC6CC(C(C(O6)C)O)OC7CC(C(C(O7)C)OC8CC(C(C(O8)C)O)(C)O)O)C(=C4C(=C3C)O)O)O)O

1 reference

stated in ^Turanci

PubChem ^Turanci

PubChem CID ^Turanci

CHEMBL1237054 (Turanci)

retrieved ^Turanci

21 Satumba 2016

isomeric SMILES ^Turanci

C[C@@H]1[C@H]([C@@H](C[C@@H](O1)O[C@@H]2C[C@@H](O[C@@H]([C@H]2O)C)OC3=CC4=CC5=C(C(=O)[C@H]([C@@H](C5)[C@@H](C(=O)[C@H]([C@@H](C)O)O)OC)O[C@H]6C[C@H]([C@@H]([C@H](O6)C)O)O[C@H]7C[C@H]([C@H]([C@H](O7)C)O)O[C@H]8C[C@]([C@@H]([C@H](O8)C)O)(C)O)C(=C4C(=C3C)O)O)O)O

0 references

World Health Organisation international non-proprietary name ^Turanci

Plicamycin (Turanci)

1 reference

stated in ^Turanci

ChEMBL ^Turanci

ChEMBL ID ^Turanci

Plicamycin (Turanci)

retrieved ^Turanci

19 Janairu 2016

found in taxon ^Turanci

Streptomyces nogalater ^Turanci

1 reference

stated in ^Turanci

Streptomyces ^Turanci

1 reference

stated in ^Turanci

Two novel C-glycosides of aureolic acid repress transcription of the MDR1 gene ^Turanci

Streptomyces argillaceus ^Turanci

4 references

stated in ^Turanci

The Structure of Mithramycin Reinvestigated ^Turanci

stated in ^Turanci

Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin ^Turanci

stated in ^Turanci

Uncovering production of specialized metabolites by Streptomyces argillaceus: Activation of cryptic biosynthesis gene clusters using nutritional and genetic approaches. ^Turanci

stated in ^Turanci

Engineering precursor metabolite pools for increasing production of antitumor mithramycins in Streptomyces argillaceus ^Turanci

Streptomyces lividans ^Turanci

1 reference

stated in ^Turanci

Increased heterologous production of the antitumoral polyketide mithramycin A by engineered Streptomyces lividans TK24 strains. ^Turanci

medical condition treated ^Turanci

Chronic myelogenous leukemia

1 reference

stated in ^Turanci

NDF-RT ^Turanci

NDF-RT ID ^Turanci

retrieved ^Turanci

13 Disamba 2016

Kansar Mahaifa

1 reference

stated in ^Turanci

NDF-RT ^Turanci

NDF-RT ID ^Turanci

retrieved ^Turanci

13 Disamba 2016

hypercalcemia ^Turanci

1 reference

stated in ^Turanci

NDF-RT ^Turanci

NDF-RT ID ^Turanci

retrieved ^Turanci

13 Disamba 2016

pregnancy category ^Turanci

US pregnancy category X ^Turanci

1 reference

an ɗauko daga

English Wikipedia ^Turanci

subject has role ^Turanci

DNA polymerase inhibitors ^Turanci

2 references

stated in ^Turanci

NDF-RT ^Turanci

NDF-RT ID ^Turanci

retrieved ^Turanci

5 Maris 2018

stated in ^Turanci

MeSH descriptor ID ^Turanci

retrieved ^Turanci

15 Maris 2018

antineoplastic antibiotics ^Turanci

1 reference

stated in ^Turanci

MeSH descriptor ID ^Turanci

retrieved ^Turanci

15 Maris 2018

fluorophore ^Turanci

1 reference

stated in ^Turanci

MeSH descriptor ID ^Turanci

retrieved ^Turanci

15 Maris 2018

protein synthesis inhibitor ^Turanci

1 reference

stated in ^Turanci

MeSH descriptor ID ^Turanci

InChI=1S/C52H76O24/c1-18-29(72-34-14-30(43(58)21(4)68-34)73-33-13-28(54)42(57)20(3)67-33)12-26-10-25-11-27(49(66-9)48(63)41(56)19(2)53)50(47(62)39(25)46(61)38(26)40(18)55)76-36-16-31(44(59)23(6)70-36)74-35-15-32(45(60)22(5)69-35)75-37-17-52(8,65)51(64)24(7)71-37/h10,12,19-24,27-28,30-37,41-45,49-51,53-61,64-65H,11,13-17H2,1-9H3/t19-,20-,21-,22-,23-,24-,27+,28-,30-,31-,32-,33+,34+,35+,36+,37+,41+,42-,43-,44-,45+,49+,50+,51-,52+/m1/s1

retrieved ^Turanci

15 Maris 2018

Identifiers

InChI ^Turanci

0 references

InChIKey ^Turanci

CFCUWKMKBJTWLW-BKHRDMLASA-N

3 references

stated in ^Turanci

PubChem ^Turanci

PubChem CID ^Turanci

163659

stated in ^Turanci

Natural Product Atlas ^Turanci

PubChem CID ^Turanci

163659