darunavir English (Q3765251)

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chemical compound English
cokic
Language Label Description Also known as
Thuɔŋjäŋ
Acïn yärërin cï nyuɔɔth etɛ̈n
Acïn tɛ̈ɛ̈tëyic cï lueel
    English
    darunavir
    chemical compound
    • MC-114
    • TMC114
    • (3R,3AS,6ar)-hexahydrofuro[2,3-b]furan-3-yl N-((1S,2R)-1-benzyl-2-hydroxy-3-(N(1)-isobutylsulfanilamido)propyl)carbamate
    • (3R,3AS,6ar)-tetrahydro-2H-furo[2,3-b]furan-3-yl (2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-ylcarbamate
    • (3R,3AS,6ar)-hexahydrofuro[2,3-b]furan-3-yl(1S,2R)-3-[[(4-aminophenyl)sulfonyl](isobutyl)amino]-1-benzyl-2-hydroxypropylcarbamate
    • [(S)-3-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-2-hydroxy-1-((R)-phenylmethyl)-propyl]-carbamic acid (3R,3as,6ar)-(hexahydro-furo[2,3-b]furan-3-yl) ester
    • N-((1S,2R)-3-(((4-Aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-benzylpropyl)((1S,2R,5R)-4,6-dioxabicyclo(3.3.0)oct-2-yloxy)carboxamide
    • {(1S,2R)-3-[(4-amino-benzenesulfonyl)-isobutyl-amino]-1-benzyl-2-hydroxy-propyl}-carbamic acid (3R,3as,6ar)-(hexahydro-furo[2,3-b]furan-3-yl) ester
    • TMC-114
    • (3R,3AS,6ar)-tetrahydro-2H-furo[2,3-b]furan-3-yl (2S,3R)-4-(4-amino-N-neopentylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-ylcarbamate
    • UIC-940T
    • Darunavir
    • Darunavirum

    Käluel

    instance of English
    type of chemical entity English
    0 references
    subclass of English
    2-epi-Darunavir English
    1 reference
    based on heuristic English
    inferred from InChIKey English
    has use English
    medication English
    1 reference
    title English
    Darunavir (English)
    stated in English
    DrugBank English
    language of work or name English
    English English
    publication date English
    17 Pɛnëthiäärkutök 2015
    DrugBank ID English
    01264
    chemical structure English
    Darunavir structure.svg
    512 × 413; 13 KB
    0 references
    mass English
    547.235 dalton
    1 reference
    stated in English
    PubChem English
    PubChem CID English
    213039
    language of work or name English
    English English
    title English
    Darunavir (English)
    retrieved English
    18 Pɛnëthiäär 2016
    chemical formula English
    C₂₇H₃₇N₃O₇S
    1 reference
    stated in English
    PubChem English
    PubChem CID English
    213039
    language of work or name English
    English English
    title English
    Darunavir (English)
    retrieved English
    19 Pɛnëthiäärkutök 2016
    canonical SMILES English
    CC(C)CN(CC(C(CC1=CC=CC=C1)NC(=O)OC2COC3C2CCO3)O)S(=O)(=O)C4=CC=C(C=C4)N
    1 reference
    stated in English
    PubChem English
    PubChem CID English
    213039
    language of work or name English
    English English
    title English
    Darunavir (English)
    retrieved English
    19 Pɛnëthiäärkutök 2016
    isomeric SMILES English
    CC(C)CN(C[C@H]([C@H](CC1=CC=CC=C1)NC(=O)O[C@H]2CO[C@@H]3[C@H]2CCO3)O)S(=O)(=O)C4=CC=C(C=C4)N
    1 reference
    stated in English
    PubChem English
    PubChem CID English
    213039
    language of work or name English
    English English
    title English
    Darunavir (English)
    retrieved English
    19 Pɛnëthiäärkutök 2016
    World Health Organisation international non-proprietary name English
    darunavir (English)
    1 reference
    stated in English
    ChEBI English
    ChEBI ID English
    367163
    language of work or name English
    English English
    title English
    darunavir (English)
    retrieved English
    18 Pɛnëthiäär 2016
    medical condition treated English
    Adarwäl
    1 reference
    stated in English
    Drug Indications Extracted from FAERS English
    retrieved English
    2 Pɛnëthiäär 2018
    LiverTox likelihood score English
    LiverTox toxicity likelihood category D English
    1 reference
    stated in English
    LiverTox English
    retrieved English
    8 Pɛnëŋuan 2021
    reference URL English
    https://www.ncbi.nlm.nih.gov/books/n/livertox/Darunavir
    last update English
    1 Pɛnëdhoŋuan 2017
    subject has role English
    HIV protease inhibitors English
    2 references
    stated in English
    NDF-RT English
    NDF-RT ID English
    N0000175996
    retrieved English
    5 Pɛnëdiäk 2018
    stated in English
    Medical Subject Headings English
    MeSH descriptor ID English
    D000069454
    retrieved English
    15 Pɛnëdiäk 2018
    essential medicine English
    0 references
    bactericide English
    1 reference
    stated in English
    ChEBI English
    ChEBI ID English
    367163
    antiviral drug English
    1 reference
    stated in English
    ChEBI English
    Commons category English
    Darunavir
    0 references
    catalog English

    Identifiers

    InChIKey English
    CJBJHOAVZSMMDJ-HEXNFIEUSA-N
    2 references
    stated in English
    PubChem English
    PubChem CID English
    213039
    language of work or name English
    English English
    title English
    Darunavir (English)
    retrieved English
    19 Pɛnëthiäärkutök 2016
    stated in English
    ChEBI release 2020-09-01 English
    CAS Registry Number English
    206361-99-1
    2 references
    stated in English
    Global Substance Registration System English
    UNII English
    YO603Y8113
    language of work or name English
    English English
    title English
    darunavir (English)
    retrieved English
    19 Pɛnëthiäärkutök 2016
    InChIKey English
    CJBJHOAVZSMMDJ-HEXNFIEUSA-N
    stated in English
    CAS Common Chemistry English
    retrieved English
    9 Pɛnëŋuan 2021
    reference URL English
    https://commonchemistry.cas.org/detail?cas_rn=206361-99-1
    ChemSpider ID English
    184733
    1 reference
    stated in English
    ChemSpider English
    ChemSpider ID English
    184733
    language of work or name English
    English English
    title English
    Darunavir (English)
    retrieved English
    19 Pɛnëthiäärkutök 2016
    PubChem CID English
    213039
    2 references
    stated in English
    PubChem English
    PubChem CID English
    213039
    language of work or name English
    English English
    title English
    Darunavir (English)
    retrieved English
    19 Pɛnëthiäärkutök 2016
    matched by identifier from English
    InChIKey
    InChIKey English
    CJBJHOAVZSMMDJ-HEXNFIEUSA-N
    Reaxys registry number English
    7960555
    1 reference
    stated in English
    ChEBI English
    ChEBI ID English
    367163
    language of work or name English
    English English
    title English
    darunavir (English)
    retrieved English
    18 Pɛnëthiäär 2016
    ChEMBL ID English
    CHEMBL1323
    1 reference
    stated in English
    ChEMBL English
    ChEMBL ID English
    CHEMBL1323
    language of work or name English
    English English
    title English
    DARUNAVIR (English)
    retrieved English
    19 Pɛnëthiäärkutök 2016
    UniChem compound ID English
    488491
    1 reference
    stated in English
    UniChem English
    HSDB ID English
    7788
    1 reference
    stated in English
    Hazardous Substances Data Bank English
    HSDB ID English
    7788
    publication date English
    28 Pɛnëthiäär 2019
    title English
    Darunavir (English)
    retrieved English
    10 Pɛnëdhiëc 2021
    LiverTox ID English
    Darunavir
    0 references
    EC number English
    606-590-1
    1 reference
    stated in English
    ECHA Substance Infocard database English
    ECHA Substance Infocard ID English
    100.111.730
    retrieved English
    27 Pɛnëthiäärkurou 2018
    title English
    Carbamic acid, N-[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl ester (English)
    quotation English
    CAS no.: 206361-99-1 (English)
    ECHA Substance Infocard ID English
    100.111.730
    1 reference
    stated in English
    ECHA Substance Infocard database English
    ECHA Substance Infocard ID English
    100.111.730
    retrieved English
    27 Pɛnëthiäärkurou 2018
    title English
    Carbamic acid, N-[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl ester (English)
    quotation English
    CAS no.: 206361-99-1 (English)
    ATC code English
    J05AE10
    1 reference
    stated in English
    DrugBank English
    DrugBank ID English
    01264
    language of work or name English
    English English
    title English
    Darunavir (English)
    publication date English
    17 Pɛnëthiäärkutök 2015
    Guide to Pharmacology Ligand ID English
    11243
    1 reference
    stated in English
    IUPHAR/BPS Guide to PHARMACOLOGY English
    retrieved English
    5 Pɛnërou 2021
    MeSH descriptor ID English
    D000069454
    subject named as English
    Darunavir
    0 references
    MeSH tree code English
    D02.065.884.438
    0 references
    D02.241.081.251.222
    0 references
    D02.886.590.700.400
    0 references
    D03.383.312.303
    0 references
    RxNorm ID English
    460132
    1 reference
    stated in English
    Global Substance Registration System English
    UNII English
    YO603Y8113
    language of work or name English
    English English
    title English
    darunavir (English)
    retrieved English
    19 Pɛnëthiäärkutök 2016
    UNII English
    YO603Y8113
    2 references
    stated in English
    Global Substance Registration System English
    UNII English
    YO603Y8113
    language of work or name English
    English English
    title English
    darunavir (English)
    retrieved English
    19 Pɛnëthiäärkutök 2016
    matched by identifier from English
    InChIKey
    InChIKey English
    CJBJHOAVZSMMDJ-HEXNFIEUSA-N
    MedlinePlus drug identifier English
    a607042
    0 references
    NDF-RT ID English
    N0000175996
    1 reference
    stated in English
    Global Substance Registration System English
    UNII English
    YO603Y8113
    language of work or name English
    English English
    title English
    darunavir (English)
    retrieved English
    19 Pɛnëthiäärkutök 2016
    Probes And Drugs ID English
    PD009930
    0 references
    DrugCentral ID English
    4143
    1 reference
    stated in English
    UniChem English
    KEGG ID English
    D03656
    1 reference
    stated in English
    ChEBI English
    ChEBI ID English
    367163
    language of work or name English
    English English
    title English
    darunavir (English)
    retrieved English
    18 Pɛnëthiäär 2016
    IEDB Epitope ID English
    231714
    1 reference
    stated in English
    Immune Epitope Database and Analysis Resource English
    IEDB Epitope ID English
    231714
    retrieved English
    1 Pɛnëtök 2022
    PDB ligand ID English
    017
    0 references
    DeCS ID English
    55875
    0 references
    Freebase ID English
    /m/0d__jn
    0 references
    Microsoft Academic ID English
    2779182219
    0 references
    2908531392
    0 references
    OpenAlex ID English
    PDB structure ID English
    4NPT
    1 reference
    stated in English
    Protein Data Bank English
    PDB structure ID English
    4NPT
    language of work or name English
    English English
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    4NPT (English)
    retrieved English
    18 Pɛnëthiäär 2016
    4DQH
    1 reference
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    Protein Data Bank English
    PDB structure ID English
    4DQH
    language of work or name English
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    4DQH (English)
    retrieved English
    18 Pɛnëthiäär 2016
    4DQE
    1 reference
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    Protein Data Bank English
    PDB structure ID English
    4DQE
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    4DQE (English)
    retrieved English
    18 Pɛnëthiäär 2016
    5E5J
    1 reference
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    5E5J
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    5E5J (English)
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    18 Pɛnëthiäär 2016
    3JW2
    1 reference
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    3JW2
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    3JW2 (English)
    retrieved English
    18 Pɛnëthiäär 2016
    2HS2
    1 reference
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    2HS2
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    2HS2 (English)
    retrieved English
    18 Pɛnëthiäär 2016
    2HS1
    1 reference
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    2HS1
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    English English
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    2HS1 (English)
    retrieved English
    18 Pɛnëthiäär 2016
    2IDW
    1 reference
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    2IDW
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    18 Pɛnëthiäär 2016
    4DQB
    1 reference
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    4DQB
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    18 Pɛnëthiäär 2016
    3LZS
    1 reference
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    18 Pɛnëthiäär 2016
    3LZV
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    18 Pɛnëthiäär 2016
    3S54
    1 reference
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    3S54
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    3S54 (English)
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    18 Pɛnëthiäär 2016
    3S53
    1 reference
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    PDB structure ID English
    3S53
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    English English
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    3S53 (English)
    retrieved English
    18 Pɛnëthiäär 2016
    3TKW
    1 reference
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    3TKW
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    3TKW (English)
    retrieved English
    18 Pɛnëthiäär 2016
    3EBZ
    1 reference
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    3EBZ
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    3EBZ (English)
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    18 Pɛnëthiäär 2016
    3CYW
    1 reference
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    3CYW
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    3CYW (English)
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    18 Pɛnëthiäär 2016
    2IEN
    1 reference
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    2IEN
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    18 Pɛnëthiäär 2016
    2IEO
    1 reference
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    18 Pɛnëthiäär 2016
    3GGU
    1 reference
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    18 Pɛnëthiäär 2016
    3U7S
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    18 Pɛnëthiäär 2016
    4Q1W
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    18 Pɛnëthiäär 2016
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    18 Pɛnëthiäär 2016
    4LL3
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    18 Pɛnëthiäär 2016
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    18 Pɛnëthiäär 2016
    3OXW
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    18 Pɛnëthiäär 2016
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    18 Pɛnëthiäär 2016
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    18 Pɛnëthiäär 2016
    4DQF
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    18 Pɛnëthiäär 2016
    4DQC
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    18 Pɛnëthiäär 2016
    2F80
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    18 Pɛnëthiäär 2016
    2F81
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    18 Pɛnëthiäär 2016
    4YOA
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    18 Pɛnëthiäär 2016
    3MWS
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    18 Pɛnëthiäär 2016
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    18 Pɛnëthiäär 2016
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    18 Pɛnëthiäär 2016
    3UCB
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    18 Pɛnëthiäär 2016
    3OGP
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    18 Pɛnëthiäär 2016
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    18 Pɛnëthiäär 2016
    5KR1
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    18 Pɛnëthiäär 2016
    4Q1X
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    18 Pɛnëthiäär 2016
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    18 Pɛnëthiäär 2016
    3T3C
    1 reference
    stated in English
    Protein Data Bank English
    PDB structure ID English
    3T3C
    language of work or name English
    English English
    title English
    3T3C (English)
    retrieved English
    18 Pɛnëthiäär 2016
    3JVY
    1 reference
    stated in English
    Protein Data Bank English
    PDB structure ID English
    3JVY
    language of work or name English
    English English
    title English
    3JVY (English)
    retrieved English
    18 Pɛnëthiäär 2016
    3TTP
    1 reference
    stated in English
    Protein Data Bank English
    PDB structure ID English
    3TTP
    language of work or name English
    English English
    title English
    3TTP (English)
    retrieved English
    18 Pɛnëthiäär 2016
    3D20
    1 reference
    stated in English
    Protein Data Bank English
    PDB structure ID English
    3D20
    language of work or name English
    English English
    title English
    3D20 (English)
    retrieved English
    18 Pɛnëthiäär 2016
    3SO9
    1 reference
    stated in English
    Protein Data Bank English
    PDB structure ID English
    3SO9
    language of work or name English
    English English
    title English
    3SO9 (English)
    retrieved English
    18 Pɛnëthiäär 2016
    5KQY
    1 reference
    stated in English
    Protein Data Bank English
    PDB structure ID English
    5KQY
    language of work or name English
    English English
    title English
    5KQY (English)
    retrieved English
    18 Pɛnëthiäär 2016
    3LZU
    1 reference
    stated in English
    Protein Data Bank English
    PDB structure ID English
    3LZU
    language of work or name English
    English English
    title English
    3LZU (English)
    retrieved English
    18 Pɛnëthiäär 2016
    3BVB
    1 reference
    stated in English
    Protein Data Bank English
    PDB structure ID English
    3BVB
    language of work or name English
    English English
    title English
    3BVB (English)
    retrieved English
    18 Pɛnëthiäär 2016
    3OY4
    1 reference
    stated in English
    Protein Data Bank English
    PDB structure ID English
    3OY4
    language of work or name English
    English English
    title English
    3OY4 (English)
    retrieved English
    18 Pɛnëthiäär 2016
    1T7I
    1 reference
    stated in English
    Protein Data Bank English
    PDB structure ID English
    1T7I
    language of work or name English
    English English
    title English
    1T7I (English)
    retrieved English
    18 Pɛnëthiäär 2016
    2F8G
    1 reference
    stated in English
    Protein Data Bank English
    PDB structure ID English
    2F8G
    language of work or name English
    English English
    title English
    2F8G (English)
    retrieved English
    18 Pɛnëthiäär 2016
    5E5K
    1 reference
    stated in English
    Protein Data Bank English
    PDB structure ID English
    5E5K
    language of work or name English
    English English
    title English
    5E5K (English)
    retrieved English
    18 Pɛnëthiäär 2016
    Quora topic ID English
    Darunavir
    1 reference
    stated in English
    Quora
    UMLS CUI English
    C1435444
    1 reference
    stated in English
    Global Substance Registration System English
    UNII English
    YO603Y8113
    language of work or name English
    English English
    title English
    darunavir (English)
    retrieved English
    19 Pɛnëthiäärkutök 2016
    WikiProjectMed ID English
    Darunavir
    0 references
     
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