Thiopurine S-methyltransferase (Q94307)

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mammalian protein found in Homo sapiens

• thiopurine S-methyltransferase
• TPMT
• S-adenosyl-L-methionine:thiopurine S-methyltransferase
• Thiopurine methyltransferase

edit

Language	Label	Description	Also known as
English	Thiopurine S-methyltransferase	mammalian protein found in Homo sapiens	thiopurine S-methyltransferase TPMT S-adenosyl-L-methionine:thiopurine S-methyltransferase Thiopurine methyltransferase

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P51580

part of

Thiopurine S-methyltransferase

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P51580

S-adenosyl-L-methionine-dependent methyltransferase

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P51580

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P51580

encoded by

TPMT

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P51580

molecular function

S-adenosylmethionine-dependent methyltransferase activity

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51580

determination method

IEA

transferase activity

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P51580

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51580

determination method

IEA

methyltransferase activity

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P51580

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51580

determination method

IEA

thiopurine S-methyltransferase activity

determination method

IDA

IEA

TAS

6 references

retrieved

24 April 2018

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51580&geneProductId=UniProtKB:P51580

determination method

TAS

retrieved

24 April 2018

stated in

Human thiopurine methyltransferase: molecular cloning and expression of T84 colon carcinoma cell cDNA

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51580&geneProductId=UniProtKB:P51580

determination method

TAS

retrieved

24 April 2018

stated in

GOA

curator

UniProt

UniProt protein ID

P51580

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51580&geneProductId=UniProtKB:P51580

determination method

IEA

retrieved

24 April 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51580&geneProductId=UniProtKB:P51580

determination method

IEA

retrieved

24 April 2018

stated in

Human erythrocyte thiopurine methyltransferase: radiochemical microassay and biochemical properties

GOA

curator

UniProt

UniProt protein ID

P51580

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51580&geneProductId=UniProtKB:P51580

determination method

IDA

retrieved

24 April 2018

stated in

Structural Basis of Substrate Recognition in Thiopurine S -Methyltransferase † ‡

GOA

curator

UniProt

UniProt protein ID

P51580

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51580&geneProductId=UniProtKB:P51580

determination method

IDA

S-adenosyl-L-methionine binding

determination method

IDA

2 references

retrieved

8 April 2019

stated in

Human erythrocyte thiopurine methyltransferase: radiochemical microassay and biochemical properties

GOA

curator

UniProt

UniProt protein ID

P51580

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51580

determination method

IDA

retrieved

8 April 2019

stated in

Structural Basis of Substrate Recognition in Thiopurine S -Methyltransferase † ‡

GOA

curator

UniProt

UniProt protein ID

P51580

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51580

determination method

IDA

thiopurine S-methyltransferase activity

determination method

IBA

IDA

IEA

TAS

7 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51580

determination method

TAS

retrieved

8 April 2019

stated in

Human thiopurine methyltransferase: molecular cloning and expression of T84 colon carcinoma cell cDNA

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51580

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P51580

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51580

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51580

determination method

IEA

retrieved

8 April 2019

stated in

Human erythrocyte thiopurine methyltransferase: radiochemical microassay and biochemical properties

GOA

curator

UniProt

UniProt protein ID

P51580

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51580

determination method

IDA

retrieved

8 April 2019

stated in

Structural Basis of Substrate Recognition in Thiopurine S -Methyltransferase † ‡

GOA

curator

UniProt

UniProt protein ID

P51580

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51580

determination method

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51580

determination method

IBA

cell component

cytosol

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51580

determination method

TAS

cytoplasm

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P51580

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51580

determination method

IEA

biological process

nucleobase-containing compound metabolic process

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

Human thiopurine methyltransferase: molecular cloning and expression of T84 colon carcinoma cell cDNA

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51580

determination method

TAS

methylation

determination method

IEA

TAS

2 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51580

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P51580

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51580

determination method

IEA

Gene Atlas image

PBB GE TPMT 203671 at fs.png
732 × 530; 11 KB

0 references

exact match

http://purl.uniprot.org/uniprot/P51580

1 reference

stated in

Identifiers.org

Identifiers

RefSeq protein ID

NP_000358

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

7172

NP_001333746

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

7172

NP_001333747

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

7172

UniProt protein ID

P51580

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P51580

Ensembl protein ID

ENSP00000312304

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000312304

Freebase ID

/m/098v0p

1 reference

stated in

Freebase Data Dumps

publication date

28 October 2013

Microsoft Academic ID

70917649

0 references

OpenAlex ID

C70917649

1 reference

stated in

OpenAlex

retrieved

26 January 2022

reference URL

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID

2BZG

1 reference

stated in

UniProt

UniProt protein ID

P51580

retrieved

4 August 2016

language of work or name

English

2H11

1 reference

stated in

UniProt

UniProt protein ID

P51580

retrieved

4 August 2016

language of work or name

English

 

Sitelinks

Wikipedia(11 entries)

edit

• cywiki TPMT
• dewiki Thiopurin-Methyltransferase
• enwiki Thiopurine methyltransferase
• eswiki Tiopurina metiltransferasa
• etwiki Tiopuriinmetüültransferaas
• fiwiki Tiopuriinimetyylitransferaasi
• itwiki Tiopurina S-metiltransferasi
• shwiki Tiopurin S-metiltransferaza
• srwiki Tiopurin S-metiltransferaza
• ukwiki TPMT
• zhwiki 硫嘌呤甲基转移酶

Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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