Heparanase (Q909646)

http://www.ebi.ac.uk/interpro/protein/Q9Y251

glycoside hydrolase superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y251

1 reference

13 November 2019

1 reference

13 November 2019

protein dimerization activity

1 reference

8 April 2019

Heterodimer formation is essential for heparanase enzymatic activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y251

beta-glucuronidase activity

1 reference

8 April 2019

Mammalian heparanase: gene cloning, expression and function in tumor progression and metastasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y251

hydrolase activity, acting on glycosyl bonds

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y251

3 references

8 April 2019

Heparanase uptake is mediated by cell membrane heparan sulfate proteoglycans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y251

8 April 2019

Heparanase enhances the generation of activated factor X in the presence of tissue factor and activated factor VII

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y251

8 April 2019

Histidine-rich glycoprotein binds heparanase and regulates its enzymatic activity and cell surface interactions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y251

1 reference

8 April 2019

Heparanase uptake is mediated by cell membrane heparan sulfate proteoglycans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y251

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y251

1 reference

8 April 2019

Structural recognition by recombinant human heparanase that plays critical roles in tumor metastasis. Hierarchical sulfate groups with different effects and the essential target disulfated trisaccharide sequence

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y251

intracellular membrane-bounded organelle

cell component

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y251

2 references

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y251

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y251

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y251

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y251

specific granule lumen

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y251

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y251

heparan sulfate proteoglycan catabolic process

IBA

biological process

1 reference

8 April 2019

Structural recognition by recombinant human heparanase that plays critical roles in tumor metastasis. Hierarchical sulfate groups with different effects and the essential target disulfated trisaccharide sequence

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y251

regulation of hair follicle development

1 reference

8 April 2019

Heparanase 1: a key participant of inner root sheath differentiation program and hair follicle homeostasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y251

positive regulation of hair follicle development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y251

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y251

IEA

vascular wound healing

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y251

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y251

positive regulation of blood coagulation

IEA

1 reference

8 April 2019

Heparanase enhances the generation of activated factor X in the presence of tissue factor and activated factor VII

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y251

proteoglycan metabolic process

1 reference

8 April 2019

Human heparanase. Purification, characterization, cloning, and expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y251

glycosaminoglycan catabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y251

positive regulation of vascular endothelial growth factor production

1 reference

8 April 2019

Heparanase induces vascular endothelial growth factor expression: correlation with p38 phosphorylation levels and Src activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y251

1 reference

24 April 2018

Heparanase mediates cell adhesion independent of its enzymatic activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y251&geneProductId=UniProtKB:Q9Y251

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y251

neutrophil degranulation

1 reference

8 April 2019

https://docs.openalex.org/download-snapshot/snapshot-data-format

Gene Atlas image

PBB GE HPSE 219403 s at fs.png
732 × 530; 11 KB

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Identifiers

1 reference

30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

1 reference

13 November 2019

1 reference

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1 reference

1 reference

1 reference

28 October 2013

Microsoft Academic ID

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1 reference

26 January 2022

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016