Baculoviral IAP repeat containing 5 (Q906904)

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mammalian protein found in Homo sapiens
  • survivin variant 3 alpha
  • baculoviral IAP repeat-containing protein 5
  • apoptosis inhibitor 4
  • BIRC5
  • apoptosis inhibitor survivin
  • BIRC5 protein, human
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Language Label Description Also known as
English
Baculoviral IAP repeat containing 5
mammalian protein found in Homo sapiens
  • survivin variant 3 alpha
  • baculoviral IAP repeat-containing protein 5
  • apoptosis inhibitor 4
  • BIRC5
  • apoptosis inhibitor survivin
  • BIRC5 protein, human

Statements

molecular function
protein binding
determination method
IPI
24 references
retrieved
9 May 2019
stated in
Aurora-B phosphorylation in vitro identifies a residue of survivin that is essential for its localization and binding to inner centromere protein (INCENP) in vivo
GOA
curator
UniProt
UniProt protein ID
O15392
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15392
determination method
IPI
retrieved
9 May 2019
stated in
Acetylation directs survivin nuclear localization to repress STAT3 oncogenic activity
GOA
curator
UniProt
UniProt protein ID
O15392
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15392
determination method
IPI
retrieved
9 May 2019
stated in
Renal uptake of the antiapoptotic protein survivin is mediated by megalin at the apical membrane of the proximal tubule.
GOA
curator
UniProt
UniProt protein ID
O15392
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15392
determination method
IPI
retrieved
9 May 2019
stated in
cIAP1 Localizes to the nuclear compartment and modulates the cell cycle
GOA
curator
UniProt
UniProt protein ID
O15392
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15392
determination method
IPI
retrieved
9 May 2019
stated in
Survivin monomer plays an essential role in apoptosis regulation
GOA
curator
UniProt
UniProt protein ID
O15392
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15392
determination method
IPI
retrieved
9 May 2019
stated in
Survivin mediates targeting of the chromosomal passenger complex to the centromere and midbody
GOA
curator
UniProt
UniProt protein ID
O15392
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15392
determination method
IPI
retrieved
9 May 2019
stated in
Aurora-C Interactions with Survivin and INCENP Reveal Shared and Distinct Features Compared with Aurora-B Chromosome Passenger Protein Complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15392
determination method
IPI
retrieved
9 May 2019
stated in
An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15392
determination method
IPI
retrieved
9 May 2019
stated in
A single amino acid change converts Aurora-A into Aurora-B-like kinase in terms of partner specificity and cellular function
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15392
determination method
IPI
retrieved
9 May 2019
stated in
Toward an understanding of the protein interaction network of the human liver
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15392
determination method
IPI
retrieved
9 May 2019
stated in
Molecular analysis of survivin isoforms: evidence that alternatively spliced variants do not play a role in mitosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15392
determination method
IPI
retrieved
9 May 2019
stated in
Phosphorylation of the CPC by Cdk1 promotes chromosome bi-orientation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15392
determination method
IPI
retrieved
9 May 2019
stated in
PAR, a protein involved in the cell cycle, is functionally related to chromosomal passenger proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15392
determination method
IPI
retrieved
9 May 2019
stated in
Spatio-temporal composition of the mitotic Chromosomal Passenger Complex detected using in situ proximity ligation assay
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15392
determination method
IPI
retrieved
9 May 2019
stated in
Interaction of Beclin 1 with survivin regulates sensitivity of human glioma cells to TRAIL-induced apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15392
determination method
IPI
retrieved
9 May 2019
stated in
Livin, a novel inhibitor of apoptosis protein family member
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15392
determination method
IPI
retrieved
9 May 2019
stated in
The GAR domain of GAS2L3 mediates binding to the chromosomal passenger complex and is required for localization of GAS2L3 to the constriction zone during abscission
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15392
determination method
IPI
retrieved
9 May 2019
stated in
Impairment of glioma stem cell survival and growth by a novel inhibitor for Survivin-Ran protein complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15392
determination method
IPI
retrieved
9 May 2019
stated in
The Survivin-Crm1 interaction is essential for chromosomal passenger complex localization and function
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15392
determination method
IPI
retrieved
9 May 2019
stated in
Cell death in leukemia: passenger protein regulation by topoisomerase inhibitors
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15392
determination method
IPI
retrieved
9 May 2019
stated in
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15392
determination method
IPI
retrieved
9 May 2019
stated in
Mps1 phosphorylates Borealin to control Aurora B activity and chromosome alignment
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15392
determination method
IPI
retrieved
9 May 2019
stated in
Structure of a Survivin-Borealin-INCENP core complex reveals how chromosomal passengers travel together
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15392
determination method
IPI
retrieved
9 May 2019
stated in
Survivin mediates targeting of the chromosomal passenger complex to the centromere and midbody
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15392
determination method
IPI
cell component
cytoplasm
determination method
IEA
IDA
6 references
retrieved
5 June 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O15392
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O15392&geneProductId=UniProtKB:O15392
determination method
IEA
retrieved
5 June 2018
stated in
Molecular analysis of survivin isoforms: evidence that alternatively spliced variants do not play a role in mitosis
GOA
curator
UniProt
UniProt protein ID
O15392
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O15392&geneProductId=UniProtKB:O15392
determination method
IDA
retrieved
5 June 2018
stated in
Expression analysis suggests a potential cytoprotective role of Birc5 in the inner ear.
GOA
curator
UniProt
UniProt protein ID
O15392
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O15392&geneProductId=UniProtKB:O15392
determination method
IDA
retrieved
5 June 2018
stated in
An otoprotective role for the apoptosis inhibitor protein survivin
GOA
curator
UniProt
UniProt protein ID
O15392
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O15392&geneProductId=UniProtKB:O15392
determination method
IDA
retrieved
5 June 2018
stated in
A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma
GOA
curator
UniProt
UniProt protein ID
O15392
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O15392&geneProductId=UniProtKB:O15392
determination method
IDA
retrieved
5 June 2018
stated in
GOA
curator
LifeDB
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O15392&geneProductId=UniProtKB:O15392
determination method
IDA
nucleus
determination method
IBA
IDA
IEA
6 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O15392
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15392
determination method
IEA
retrieved
9 May 2019
stated in
Expression analysis suggests a potential cytoprotective role of Birc5 in the inner ear.
GOA
curator
UniProt
UniProt protein ID
O15392
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15392
determination method
IDA
retrieved
9 May 2019
stated in
Acetylation directs survivin nuclear localization to repress STAT3 oncogenic activity
GOA
curator
UniProt
UniProt protein ID
O15392
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15392
determination method
IDA
retrieved
9 May 2019
stated in
An otoprotective role for the apoptosis inhibitor protein survivin
GOA
curator
UniProt
UniProt protein ID
O15392
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15392
determination method
IDA
retrieved
9 May 2019
stated in
cIAP1 Localizes to the nuclear compartment and modulates the cell cycle
GOA
curator
UniProt
UniProt protein ID
O15392
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15392
determination method
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15392
determination method
IBA
biological process
Gene Atlas image
PBB GE BIRC5 202095 s at fs.png
732 × 530; 11 KB
0 references

Identifiers

MeSH descriptor ID
C107489
subject named as
BIRC5 protein, human
0 references
DeCS ID
57504
0 references
Freebase ID
/m/026zyby
0 references
PDB structure ID
 
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