tumor protein p63 (Q7671094)

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mammalian protein found in Homo sapiens
  • TP63
  • tumor protein p53-competing protein
  • keratinocyte transcription factor KET
  • Tumor protein p73-like
  • tumor protein 63
  • chronic ulcerative stomatitis protein
  • p51
  • amplified in squamous cell carcinoma
  • p73L
  • CUSP
  • p40
  • transformation-related protein 63
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Language Label Description Also known as
English
tumor protein p63
mammalian protein found in Homo sapiens
  • TP63
  • tumor protein p53-competing protein
  • keratinocyte transcription factor KET
  • Tumor protein p73-like
  • tumor protein 63
  • chronic ulcerative stomatitis protein
  • p51
  • amplified in squamous cell carcinoma
  • p73L
  • CUSP
  • p40
  • transformation-related protein 63

Statements

molecular function
protein binding
determination method
IPI
9 references
retrieved
8 April 2019
stated in
ASPP1 and ASPP2: common activators of p53 family members
GOA
curator
UniProt
UniProt protein ID
Q9H3D4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4
determination method
IPI
retrieved
8 April 2019
stated in
HIPK2 phosphorylates ΔNp63α and promotes its degradation in response to DNA damage.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4
determination method
IPI
retrieved
8 April 2019
stated in
Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4
determination method
IPI
retrieved
8 April 2019
stated in
PKCδ stabilizes TAp63 to promote cell apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4
determination method
IPI
retrieved
8 April 2019
stated in
Identification of DeltaNp63alpha protein interactions by mass spectrometry
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4
determination method
IPI
retrieved
8 April 2019
stated in
The E3 ubiquitin ligase Itch controls the protein stability of p63
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4
determination method
IPI
retrieved
8 April 2019
stated in
A Pin1/mutant p53 axis promotes aggressiveness in breast cancer
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4
determination method
IPI
retrieved
8 April 2019
stated in
Toward an understanding of the protein interaction network of the human liver
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4
determination method
IPI
retrieved
8 April 2019
stated in
A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4
determination method
IPI
cell component
nucleus
determination method
NAS
IDA
IEA
7 references
retrieved
8 April 2019
stated in
p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities
GOA
curator
UniProt
UniProt protein ID
Q9H3D4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4
determination method
NAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9H3D4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4
determination method
IEA
retrieved
8 April 2019
stated in
A C-terminal inhibitory domain controls the activity of p63 by an intramolecular mechanism
GOA
curator
UniProt
UniProt protein ID
Q9H3D4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4
determination method
IDA
retrieved
8 April 2019
stated in
Expression of the p53 homologue p63alpha and deltaNp63alpha in normal and neoplastic cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4
determination method
IDA
retrieved
8 April 2019
stated in
p63 is a prostate basal cell marker and is required for prostate development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4
determination method
IDA
biological process

Identifiers

 
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