transcription factor 4 (Q7669683)

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mammalian protein found in Homo sapiens
  • ITF-2
  • class B basic helix-loop-helix protein 19
  • TCF4
  • immunoglobulin transcription factor 2
  • bHLHb19
  • SEF-2
  • SL3-3 enhancer factor 2
  • Transcription factor 4
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Language Label Description Also known as
English
transcription factor 4
mammalian protein found in Homo sapiens
  • ITF-2
  • class B basic helix-loop-helix protein 19
  • TCF4
  • immunoglobulin transcription factor 2
  • bHLHb19
  • SEF-2
  • SL3-3 enhancer factor 2
  • Transcription factor 4

Statements

molecular function
protein binding
determination method
IPI
13 references
retrieved
8 April 2019
stated in
Mutations affecting the BHLHA9 DNA-binding domain cause MSSD, mesoaxial synostotic syndactyly with phalangeal reduction, Malik-Percin type
GOA
curator
UniProt
UniProt protein ID
P15884
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15884
determination method
IPI
retrieved
8 April 2019
stated in
The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/β-catenin coactivators essential for intestinal homeostasis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15884
determination method
IPI
retrieved
8 April 2019
stated in
Bcr-Abl stabilizes beta-catenin in chronic myeloid leukemia through its tyrosine phosphorylation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15884
determination method
IPI
retrieved
8 April 2019
stated in
Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15884
determination method
IPI
retrieved
8 April 2019
stated in
Kindlin 2 forms a transcriptional complex with β-catenin and TCF4 to enhance Wnt signalling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15884
determination method
IPI
retrieved
8 April 2019
stated in
Microsomal prostaglandin E synthase-1 promotes hepatocarcinogenesis through activation of a novel EGR1/β-catenin signaling axis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15884
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15884
determination method
IPI
retrieved
8 April 2019
stated in
Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15884
determination method
IPI
retrieved
8 April 2019
stated in
In silico prediction of physical protein interactions and characterization of interactome orphans
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15884
determination method
IPI
retrieved
8 April 2019
stated in
miR-182-5p promotes hepatocellular carcinoma progression by repressing FOXO3a.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15884
determination method
IPI
retrieved
8 April 2019
stated in
HASH-1 and E2-2 are expressed in human neuroblastoma cells and form a functional complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15884
determination method
IPI
retrieved
8 April 2019
stated in
Toward an understanding of the protein interaction network of the human liver
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15884
determination method
IPI
retrieved
8 April 2019
stated in
Functional interaction of DNA topoisomerase IIalpha with the beta-catenin and T-cell factor-4 complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15884
determination method
IPI
cell component
biological process

Identifiers

MeSH descriptor ID
D000073940
subject named as
Transcription Factor 4
0 references
RefSeq protein ID
Ensembl protein ID
 
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