solute carrier family 22 member 5 (Q7390798)

From Wikidata

Jump to navigation Jump to search

mammalian protein found in Homo sapiens

• High-affinity sodium-dependent carnitine cotransporter
• organic cation/carnitine transporter 2
• high-affinity sodium dependent carnitine cotransporter
• SLC22A5
• Solute carrier family 22 member 5

edit

Language	Label	Description	Also known as
English	solute carrier family 22 member 5	mammalian protein found in Homo sapiens	High-affinity sodium-dependent carnitine cotransporter organic cation/carnitine transporter 2 high-affinity sodium dependent carnitine cotransporter SLC22A5 Solute carrier family 22 member 5

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O76082

part of

organic cation transport protein/SVOP

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O76082

Organic Cation Transporter

1 reference

Transporter Classification Database ID

2.A.1.19.3

retrieved

2 October 2019

based on heuristic

hierarchical database ID heuristic

Major facilitator superfamily domain

1 reference

based on heuristic

inferred from protein domain or family

Sugar transporter, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O76082

encoded by

SLC22A5

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O76082

molecular function

nucleotide binding

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O76082

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IEA

PDZ domain binding

determination method

IPI

1 reference

retrieved

9 May 2019

stated in

PDZK1 directly regulates the function of organic cation/carnitine transporter OCTN2

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IPI

transmembrane transporter activity

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IEA

transporter activity

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IEA

protein binding

determination method

IPI

1 reference

retrieved

9 May 2019

stated in

PDZK1 directly regulates the function of organic cation/carnitine transporter OCTN2

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IPI

quaternary ammonium group transmembrane transporter activity

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

cDNA sequence, transport function, and genomic organization of human OCTN2, a new member of the organic cation transporter family

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IDA

symporter activity

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O76082

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IEA

ATP binding

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O76082

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IEA

xenobiotic transmembrane transporter activity

determination method

IC

2 references

retrieved

8 April 2019

stated in

L-Carnitine transport in human placental brush-border membranes is mediated by the sodium-dependent organic cation transporter OCTN2

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IC

retrieved

9 May 2019

stated in

L-Carnitine transport in human placental brush-border membranes is mediated by the sodium-dependent organic cation transporter OCTN2

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IC

organic anion transmembrane transporter activity

determination method

IBA

1 reference

retrieved

26 September 2017

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O76082&geneProductId=UniProtKB:O76082

determination method

IBA

carnitine transmembrane transporter activity

determination method

EXP

IDA

IMP

TAS

4 references

retrieved

1 January 2018

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O76082&geneProductId=UniProtKB:O76082

determination method

TAS

retrieved

1 January 2018

stated in

Primary systemic carnitine deficiency is caused by mutations in a gene encoding sodium ion-dependent carnitine transporter

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O76082&geneProductId=UniProtKB:O76082

determination method

IMP

retrieved

1 January 2018

stated in

Molecular and functional identification of sodium ion-dependent, high affinity human carnitine transporter OCTN2

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O76082&geneProductId=UniProtKB:O76082

determination method

IDA

retrieved

1 January 2018

stated in

Molecular and functional identification of sodium ion-dependent, high affinity human carnitine transporter OCTN2

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O76082&geneProductId=UniProtKB:O76082

determination method

EXP

carnitine transmembrane transporter activity

determination method

EXP

IDA

IMP

3 references

retrieved

9 May 2019

stated in

Primary systemic carnitine deficiency is caused by mutations in a gene encoding sodium ion-dependent carnitine transporter

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IMP

retrieved

9 May 2019

stated in

Molecular and functional identification of sodium ion-dependent, high affinity human carnitine transporter OCTN2

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IDA

retrieved

9 May 2019

stated in

Molecular and functional identification of sodium ion-dependent, high affinity human carnitine transporter OCTN2

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

EXP

quaternary ammonium group transmembrane transporter activity

determination method

IBA

IDA

2 references

retrieved

9 May 2019

stated in

cDNA sequence, transport function, and genomic organization of human OCTN2, a new member of the organic cation transporter family

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IDA

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IBA

cell component

integral component of membrane

determination method

IEA

2 references

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O76082

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IEA

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IEA

membrane

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O76082

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IEA

plasma membrane

determination method

IC

TAS

3 references

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

TAS

retrieved

9 May 2019

stated in

Primary systemic carnitine deficiency is caused by mutations in a gene encoding sodium ion-dependent carnitine transporter

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

TAS

retrieved

9 May 2019

stated in

cDNA sequence, transport function, and genomic organization of human OCTN2, a new member of the organic cation transporter family

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IC

integral component of plasma membrane

determination method

IBA

1 reference

retrieved

26 September 2017

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O76082&geneProductId=UniProtKB:O76082

determination method

IBA

brush border membrane

determination method

IDA

ISS

2 references

retrieved

9 May 2019

stated in

PDZK1 directly regulates the function of organic cation/carnitine transporter OCTN2

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

ISS

retrieved

9 May 2019

stated in

L-Carnitine transport in human placental brush-border membranes is mediated by the sodium-dependent organic cation transporter OCTN2

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IDA

apical plasma membrane

determination method

IDA

2 references

retrieved

9 May 2019

stated in

Expression and localization of carnitine/organic cation transporter OCTN1 and OCTN2 in ocular epithelium

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IDA

retrieved

9 May 2019

stated in

OCTN2-mediated carnitine uptake in a newly discovered human proximal tubule cell line (Caki-1)

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IDA

extracellular exosome

determination method

IDA

1 reference

retrieved

26 September 2017

stated in

Large-scale proteomics and phosphoproteomics of urinary exosomes

GOA

curator

UniProt

UniProt protein ID

O76082

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O76082&geneProductId=UniProtKB:O76082

determination method

IDA

extracellular exosome

determination method

HDA

1 reference

retrieved

9 May 2019

stated in

Large-scale proteomics and phosphoproteomics of urinary exosomes

GOA

curator

UniProt

UniProt protein ID

O76082

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

HDA

biological process

sodium ion transport

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O76082

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IEA

quaternary ammonium group transport

determination method

IDA

1 reference

retrieved

9 May 2019

stated in

cDNA sequence, transport function, and genomic organization of human OCTN2, a new member of the organic cation transporter family

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IDA

ion transport

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O76082

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IEA

sodium-dependent organic cation transport

determination method

IDA

2 references

retrieved

9 May 2019

stated in

Molecular and functional identification of sodium ion-dependent, high affinity human carnitine transporter OCTN2

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IDA

retrieved

9 May 2019

stated in

L-Carnitine transport in human placental brush-border membranes is mediated by the sodium-dependent organic cation transporter OCTN2

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IDA

positive regulation of intestinal epithelial structure maintenance

determination method

IMP

1 reference

retrieved

9 May 2019

stated in

The Bacillus subtilis quorum-sensing molecule CSF contributes to intestinal homeostasis via OCTN2, a host cell membrane transporter

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IMP

carnitine transport

determination method

IDA

IMP

2 references

retrieved

8 April 2019

stated in

Primary systemic carnitine deficiency is caused by mutations in a gene encoding sodium ion-dependent carnitine transporter

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IMP

retrieved

8 April 2019

stated in

Molecular and functional identification of sodium ion-dependent, high affinity human carnitine transporter OCTN2

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IDA

carnitine metabolic process

determination method

IBA

1 reference

retrieved

26 September 2017

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O76082&geneProductId=UniProtKB:O76082

determination method

IBA

xenobiotic transmembrane transport

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IEA

transmembrane transport

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IEA

organic anion transport

determination method

IEA

1 reference

retrieved

26 September 2017

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O76082&geneProductId=UniProtKB:O76082

determination method

IEA

carnitine transmembrane transport

determination method

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

TAS

transport

determination method

IEA

1 reference

retrieved

26 September 2017

stated in

GOA

curator

UniProt

UniProt protein ID

O76082

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O76082&geneProductId=UniProtKB:O76082

determination method

IEA

carnitine transport

determination method

IBA

IDA

IMP

3 references

retrieved

9 May 2019

stated in

Primary systemic carnitine deficiency is caused by mutations in a gene encoding sodium ion-dependent carnitine transporter

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IMP

retrieved

9 May 2019

stated in

Molecular and functional identification of sodium ion-dependent, high affinity human carnitine transporter OCTN2

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IDA

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IBA

xenobiotic transport

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76082

determination method

IEA

Gene Atlas image

PBB GE SLC22A5 205074 at fs.png
732 × 530; 11 KB

0 references

has part(s)

major facilitator superfamily domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O76082

sugar transporter, conserved site

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O76082

Identifiers

MeSH descriptor ID

D000074058

subject named as

Solute Carrier Family 22 Member 5

0 references

MeSH tree code

D12.776.157.530.450.250.812.750

0 references

D12.776.157.530.937.612.750

0 references

D12.776.543.585.450.250.812.750

0 references

D12.776.543.585.937.701.750

0 references

RefSeq protein ID

NP_001295051

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

6584

NP_003051

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

6584

XP_011541892

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

6584

XP_016865267

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

6584

UniProt protein ID

O76082

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O76082

Ensembl protein ID

ENSP00000245407

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000245407

ENSP00000402760

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000402760

ENSP00000388838

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000388838

ENSP00000389284

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000389284

ENSP00000400553

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000400553

ENSP00000401860

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000401860

Transporter Classification Database ID

2.A.1.19.3

2 references

stated in

Transporter Classification database

retrieved

13 March 2020

stated in

Transporter Classification database

retrieved

29 April 2020

UMLS CUI

C4319821

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

stated in

UMLS 2023

retrieved

25 May 2023

 

Sitelinks

Wikipedia(0 entries)

edit

Wikibooks(0 entries)

edit

Wikinews(0 entries)

edit

Wikiquote(0 entries)

edit

Wikisource(0 entries)

edit

Wikiversity(0 entries)

edit

Wikivoyage(0 entries)

edit

Wiktionary(0 entries)

edit

Multilingual sites(0 entries)

edit

Retrieved from "https://www.wikidata.org/w/index.php?title=Q7390798&oldid=2022910129"