Nuclear receptor subfamily 1 group D member 2 (Q7317662)

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mammalian protein found in Homo sapiens

rev-erb-beta
orphan nuclear hormone receptor BD73
EAR-1R
nuclear receptor subfamily 1 group D member 2
nuclear receptor Rev-ErbA beta variant 2
rev-erb alpha-related receptor
rev-erba-alpha-related receptor
RVR
nuclear receptor Rev-ErbA beta variant 1
V-erbA-related protein 1-related
NR1D2

Language	Label	Description	Also known as
English	Nuclear receptor subfamily 1 group D member 2	mammalian protein found in Homo sapiens	rev-erb-beta orphan nuclear hormone receptor BD73 EAR-1R nuclear receptor subfamily 1 group D member 2 nuclear receptor Rev-ErbA beta variant 2 rev-erb alpha-related receptor rev-erba-alpha-related receptor RVR nuclear receptor Rev-ErbA beta variant 1 V-erbA-related protein 1-related NR1D2

Statements

1 reference

13 November 2019

UniProt protein ID

0 references

Nuclear hormone receptor-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q14995

Zinc finger, NHR/GATA-type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q14995

nuclear receptor

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q14995

Nuclear hormone receptor, ligand-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Zinc finger, nuclear hormone receptor-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

sequence-specific DNA binding

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

zinc ion binding

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

metal ion binding

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

steroid hormone receptor activity

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

nuclear receptor activity

determination method

1 reference

9 May 2019

A new orphan member of the nuclear hormone receptor superfamily closely related to Rev-Erb

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

core promoter sequence-specific DNA binding

determination method

3 references

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14995&geneProductId=UniProtKB:Q14995

determination method

24 April 2018

The orphan nuclear receptor Rev-erbbeta recruits Tip60 and HDAC1 to regulate apolipoprotein CIII promoter

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14995&geneProductId=UniProtKB:Q14995

determination method

24 April 2018

A zinc finger HIT domain-containing protein, ZNHIT-1, interacts with orphan nuclear hormone receptor Rev-erbbeta and removes Rev-erbbeta-induced inhibition of apoCIII transcription

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14995&geneProductId=UniProtKB:Q14995

determination method

protein binding

determination method

5 references

9 May 2019

Ubiquitin ligase Siah2 regulates RevErbα degradation and the mammalian circadian clock

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

9 May 2019

The orphan nuclear receptor Rev-erbbeta recruits Tip60 and HDAC1 to regulate apolipoprotein CIII promoter

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

9 May 2019

A zinc finger HIT domain-containing protein, ZNHIT-1, interacts with orphan nuclear hormone receptor Rev-erbbeta and removes Rev-erbbeta-induced inhibition of apoCIII transcription

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

9 May 2019

Dynamic circadian protein-protein interaction networks predict temporal organization of cellular functions

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

9 May 2019

A Y2H-seq approach defines the human protein methyltransferase interactome

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

RNA polymerase II cis-regulatory region sequence-specific DNA binding

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

DNA-binding transcription factor activity, RNA polymerase II-specific

determination method

3 references

5 June 2018

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14995&geneProductId=UniProtKB:Q14995

determination method

5 June 2018

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14995&geneProductId=UniProtKB:Q14995

determination method

5 June 2018

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14995&geneProductId=UniProtKB:Q14995

determination method

RNA polymerase II cis-regulatory region sequence-specific DNA binding

determination method

cis-regulatory region sequence-specific DNA binding

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

transcription cis-regulatory region binding

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

RNA polymerase II transcription regulatory region sequence-specific DNA binding

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

DNA-binding transcription factor activity, RNA polymerase II-specific

determination method

4 references

9 May 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

9 May 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

9 May 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

DNA-binding transcription repressor activity, RNA polymerase II-specific

determination method

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14995&geneProductId=UniProtKB:Q14995

determination method

transcription factor binding

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

nuclear receptor coactivator activity

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

signaling receptor activity

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

determination method

5 references

5 June 2018

A new orphan member of the nuclear hormone receptor superfamily closely related to Rev-Erb

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14995&geneProductId=UniProtKB:Q14995

determination method

5 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14995&geneProductId=UniProtKB:Q14995

determination method

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14995&geneProductId=UniProtKB:Q14995

determination method

5 June 2018

A zinc finger HIT domain-containing protein, ZNHIT-1, interacts with orphan nuclear hormone receptor Rev-erbbeta and removes Rev-erbbeta-induced inhibition of apoCIII transcription

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14995&geneProductId=UniProtKB:Q14995

determination method

5 June 2018

The orphan nuclear receptor Rev-erbbeta recruits Tip60 and HDAC1 to regulate apolipoprotein CIII promoter

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14995&geneProductId=UniProtKB:Q14995

determination method

determination method

7 references

9 May 2019

A new orphan member of the nuclear hormone receptor superfamily closely related to Rev-Erb

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

9 May 2019

The orphan nuclear receptor Rev-erbbeta recruits Tip60 and HDAC1 to regulate apolipoprotein CIII promoter

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

9 May 2019

A zinc finger HIT domain-containing protein, ZNHIT-1, interacts with orphan nuclear hormone receptor Rev-erbbeta and removes Rev-erbbeta-induced inhibition of apoCIII transcription

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

RNA polymerase II transcription regulator complex

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

determination method

biological process

regulation of transcription, DNA-templated

determination method

rhythmic process

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

transcription, DNA-templated

determination method

1 reference

5 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14995&geneProductId=UniProtKB:Q14995

determination method

transcription initiation from RNA polymerase II promoter

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

negative regulation of transcription, DNA-templated

determination method

3 references

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

9 May 2019

The orphan nuclear receptor Rev-erbbeta recruits Tip60 and HDAC1 to regulate apolipoprotein CIII promoter

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

9 May 2019

A zinc finger HIT domain-containing protein, ZNHIT-1, interacts with orphan nuclear hormone receptor Rev-erbbeta and removes Rev-erbbeta-induced inhibition of apoCIII transcription

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

steroid hormone mediated signaling pathway

determination method

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

intracellular receptor signaling pathway

determination method

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

negative regulation of transcription by RNA polymerase II

determination method

1 reference

5 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14995&geneProductId=UniProtKB:Q14995

determination method

multicellular organism development

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

hormone-mediated signaling pathway

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

cell differentiation

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

response to lipid

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

regulation of circadian rhythm

determination method

3 references

positive regulation of transcription by RNA polymerase II

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

negative regulation of inflammatory response

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14995

determination method

physically interacts with

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

Gene Atlas image

PBB GE NR1D2 209750 at fs.png
732 × 530; 11 KB

0 references

nuclear hormone receptor-type zinc finger

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q14995

Nuclear hormone receptor, ligand-binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q14995

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000310006

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000310006

ENSP00000373283

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000373283

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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