Downregulation of telomerase reverse transcriptase mRNA expression by wild type p53 in human tumor cells (Q73155202)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11064449%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

title

Downregulation of telomerase reverse transcriptase mRNA expression by wild type p53 in human tumor cells (English)

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1 November 2019

5

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1 November 2019

Galina Selivanova

7

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1 November 2019

Klas Wiman

9

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1 November 2019

author name string

Xu D

1

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1 November 2019

Wang Q

2

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1 November 2019

Gruber A

3

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1 November 2019

Björkholm M

4

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1 November 2019

Zaid A

6

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1 November 2019

Peterson C

8

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1 November 2019

Pisa P

10

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1 November 2019

language of work or name

English

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publication date

1 October 2000

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1 November 2019

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1 November 2019

volume

19

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1 November 2019

issue

45

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1 November 2019

page(s)

5123-5133

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1203890

1 November 2019

exact match

0 references

cites work

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Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines

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The human telomerase catalytic subunit hTERT: organization of the gene and characterization of the promoter

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Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif

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Telomerase activity during spontaneous immortalization of Li-Fraumeni syndrome skin fibroblasts

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Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation.

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Telomerase activity in the regenerative basal layer of the epidermis inhuman skin and in immortal and carcinoma-derived skin keratinocytes

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Telomerase, Cell Immortality, and Cancer

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Lack of cell cycle regulation of telomerase activity in human cells

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Specific association of human telomerase activity with immortal cells and cancer

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Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

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Telomerase activation by the E6 gene product of human papillomavirus type 16.

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p53: puzzle and paradigm

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7 January 2021

Expression of TERT in early premalignant lesions and a subset of cells in normal tissues.

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p53, the cellular gatekeeper for growth and division

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7 January 2021

Molecular interactions between telomerase and the tumor suppressor protein p53 in vitro

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7 January 2021

Genetic changes associated with telomerase activity in breast cancer

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7 January 2021

hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization

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7 January 2021

Telomerase catalytic subunit homologs from fission yeast and human

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7 January 2021

A reassessment of the telomere hypothesis of senescence

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7 January 2021

Telomerase activity in relation to p53 status and clinico-pathological parameters in breast cancer

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7 January 2021

Wild-type p53-induced apoptosis in a Burkitt lymphoma cell line is inhibited by interferon gamma

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7 January 2021

Restoration of the growth suppression function of mutant p53 by a synthetic peptide derived from the p53 C-terminal domain

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7 January 2021

Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

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7 January 2021

Myc activates telomerase

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7 January 2021

Genomic organization and promoter characterization of the gene encoding the human telomerase reverse transcriptase (hTERT).

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7 January 2021

Direct activation of TERT transcription by c-MYC.

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7 January 2021

Associations among telomerase activity, p53 protein overexpression, and genetic instability in lung cancer

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7 January 2021

Telomerase activity and the expression of telomerase components in acute myelogenous leukaemia

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7 January 2021

Suppression of telomerase reverse transcriptase (hTERT) expression in differentiated HL-60 cells: regulatory mechanisms

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