RE1 silencing transcription factor (Q7276268)

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mammalian protein found in Homo sapiens
  • RE1-silencing transcription factor variant E1b/E2/E3/N3b/E4i
  • RE1-silencing transcription factor variant E1a/E2/E3/N3a/E4i
  • RE1-silencing transcription factor variant E1c/E2/E3/E5
  • RE1-silencing transcription factor variant E1a/E2/E3/N3c/E4
  • RE1-silencing transcription factor variant E1a/E2d/E4g
  • RE1-silencing transcription factor variant E1a/E2f/E4e
  • repressor binding to the X2 box
  • RE1-silencing transcription factor variant E1a/E2a/E2k
  • RE1-silencing transcription factor variant E1b/E2a/E2k
  • neuron restrictive silencer factor
  • X2 box repressor
  • RE1-silencing transcription factor variant E1a/E2/E3/E4c
  • RE1-silencing transcription factor variant E1c/E2g/E3/E4
  • RE1-silencing transcription factor variant E1b/E2e/E4h
  • RE1-silencing transcription factor variant E1b/E2/E3/N3c/E4
  • RE1-silencing transcription factor variant E1a/E2/E3/E5
  • RE1-silencing transcription factor variant E1c/E2a/E2k
  • neural-restrictive silencer factor
  • RE1-silencing transcription factor variant E1a/E2k/E2i/E3/E4j
  • RE1-silencing transcription factor variant E1b/E2c/E2j/E3/E4
  • RE1-silencing transcription factor variant E1b/E2/E3/E5
  • RE1-silencing transcription factor variant E1a/E2/E5
  • RE1-silencing transcription factor
  • REST
  • RE1-silencing transcription factor variant E1a/E2e/E4h
  • RE1-silencing transcription factor variant E1a/E2/E4
edit
Language Label Description Also known as
English
RE1 silencing transcription factor
mammalian protein found in Homo sapiens
  • RE1-silencing transcription factor variant E1b/E2/E3/N3b/E4i
  • RE1-silencing transcription factor variant E1a/E2/E3/N3a/E4i
  • RE1-silencing transcription factor variant E1c/E2/E3/E5
  • RE1-silencing transcription factor variant E1a/E2/E3/N3c/E4
  • RE1-silencing transcription factor variant E1a/E2d/E4g
  • RE1-silencing transcription factor variant E1a/E2f/E4e
  • repressor binding to the X2 box
  • RE1-silencing transcription factor variant E1a/E2a/E2k
  • RE1-silencing transcription factor variant E1b/E2a/E2k
  • neuron restrictive silencer factor
  • X2 box repressor
  • RE1-silencing transcription factor variant E1a/E2/E3/E4c
  • RE1-silencing transcription factor variant E1c/E2g/E3/E4
  • RE1-silencing transcription factor variant E1b/E2e/E4h
  • RE1-silencing transcription factor variant E1b/E2/E3/N3c/E4
  • RE1-silencing transcription factor variant E1a/E2/E3/E5
  • RE1-silencing transcription factor variant E1c/E2a/E2k
  • neural-restrictive silencer factor
  • RE1-silencing transcription factor variant E1a/E2k/E2i/E3/E4j
  • RE1-silencing transcription factor variant E1b/E2c/E2j/E3/E4
  • RE1-silencing transcription factor variant E1b/E2/E3/E5
  • RE1-silencing transcription factor variant E1a/E2/E5
  • RE1-silencing transcription factor
  • REST
  • RE1-silencing transcription factor variant E1a/E2e/E4h
  • RE1-silencing transcription factor variant E1a/E2/E4

Statements

molecular function
protein binding
determination method
IPI
10 references
retrieved
1 January 2018
stated in
Zinc-finger protein 90 negatively regulates neuron-restrictive silencer factor-mediated transcriptional repression of fetal cardiac genes
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IPI
retrieved
1 January 2018
stated in
CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IPI
retrieved
1 January 2018
stated in
Characterization of the REST/NRSF-interacting LIM domain protein (RILP): localization and interaction with REST/NRSF
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IPI
retrieved
1 January 2018
stated in
Dual role of NRSF/REST in activation and repression of the glucocorticoid response
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IPI
retrieved
1 January 2018
stated in
The co-repressor mSin3A is a functional component of the REST-CoREST repressor complex
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IPI
retrieved
1 January 2018
stated in
CoREST: a functional corepressor required for regulation of neural-specific gene expression
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IPI
retrieved
1 January 2018
stated in
REST repression of neuronal genes requires components of the hSWI.SNF complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IPI
retrieved
1 January 2018
stated in
The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IPI
retrieved
1 January 2018
stated in
SCFbeta-TRCP controls oncogenic transformation and neural differentiation through REST degradation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IPI
retrieved
1 January 2018
stated in
Control of chromosome stability by the beta-TrCP-REST-Mad2 axis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IPI
DNA-binding transcription repressor activity, RNA polymerase II-specific
determination method
IEA
IDA
8 references
retrieved
10 September 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13127&geneProductId=UniProtKB:Q13127
determination method
IEA
retrieved
10 September 2018
stated in
CoREST: a functional corepressor required for regulation of neural-specific gene expression
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13127&geneProductId=UniProtKB:Q13127
determination method
IDA
retrieved
10 September 2018
stated in
Zinc-finger protein 90 negatively regulates neuron-restrictive silencer factor-mediated transcriptional repression of fetal cardiac genes
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13127&geneProductId=UniProtKB:Q13127
determination method
IDA
retrieved
10 September 2018
stated in
The co-repressor mSin3A is a functional component of the REST-CoREST repressor complex
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13127&geneProductId=UniProtKB:Q13127
determination method
IDA
retrieved
1 January 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IEA
retrieved
1 January 2018
stated in
Zinc-finger protein 90 negatively regulates neuron-restrictive silencer factor-mediated transcriptional repression of fetal cardiac genes
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IDA
retrieved
1 January 2018
stated in
The co-repressor mSin3A is a functional component of the REST-CoREST repressor complex
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IDA
retrieved
1 January 2018
stated in
CoREST: a functional corepressor required for regulation of neural-specific gene expression
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IDA
cell component
nucleus
determination method
IEA
IDA
NAS
10 references
retrieved
21 June 2018
stated in
The neuron-restrictive silencer factor (NRSF): a coordinate repressor of multiple neuron-specific genes
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13127&geneProductId=UniProtKB:Q13127
determination method
NAS
retrieved
21 June 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13127&geneProductId=UniProtKB:Q13127
determination method
IEA
retrieved
21 June 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13127&geneProductId=UniProtKB:Q13127
determination method
IEA
retrieved
21 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13127&geneProductId=UniProtKB:Q13127
determination method
IEA
retrieved
21 June 2018
stated in
REST: a mammalian silencer protein that restricts sodium channel gene expression to neurons
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13127&geneProductId=UniProtKB:Q13127
determination method
IDA
retrieved
21 June 2018
stated in
Regulation of aldosterone and cortisol production by the transcriptional repressor neuron restrictive silencer factor
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13127&geneProductId=UniProtKB:Q13127
determination method
IDA
retrieved
21 June 2018
stated in
Characterization of the REST/NRSF-interacting LIM domain protein (RILP): localization and interaction with REST/NRSF
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13127&geneProductId=UniProtKB:Q13127
determination method
IDA
retrieved
21 June 2018
stated in
Zinc-finger protein 90 negatively regulates neuron-restrictive silencer factor-mediated transcriptional repression of fetal cardiac genes
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13127&geneProductId=UniProtKB:Q13127
determination method
IDA
retrieved
21 June 2018
stated in
Dual role of NRSF/REST in activation and repression of the glucocorticoid response
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13127&geneProductId=UniProtKB:Q13127
determination method
IDA
retrieved
21 June 2018
stated in
The co-repressor mSin3A is a functional component of the REST-CoREST repressor complex
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13127&geneProductId=UniProtKB:Q13127
determination method
IDA
nucleus
determination method
IBA
IDA
IEA
NAS
12 references
retrieved
1 January 2018
stated in
The neuron-restrictive silencer factor (NRSF): a coordinate repressor of multiple neuron-specific genes
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
NAS
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IEA
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IEA
retrieved
1 January 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IEA
retrieved
1 January 2018
stated in
Zinc-finger protein 90 negatively regulates neuron-restrictive silencer factor-mediated transcriptional repression of fetal cardiac genes
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IDA
retrieved
1 January 2018
stated in
Characterization of the REST/NRSF-interacting LIM domain protein (RILP): localization and interaction with REST/NRSF
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IDA
retrieved
1 January 2018
stated in
Dual role of NRSF/REST in activation and repression of the glucocorticoid response
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IDA
retrieved
1 January 2018
stated in
REST: a mammalian silencer protein that restricts sodium channel gene expression to neurons
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IDA
retrieved
1 January 2018
stated in
Regulation of aldosterone and cortisol production by the transcriptional repressor neuron restrictive silencer factor
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IDA
retrieved
1 January 2018
stated in
The co-repressor mSin3A is a functional component of the REST-CoREST repressor complex
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IDA
retrieved
1 January 2018
stated in
REST is a hypoxia-responsive transcriptional repressor
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IDA
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IBA
biological process
negative regulation of transcription, DNA-templated
determination method
IEA
IDA
IMP
NAS
10 references
retrieved
1 January 2018
stated in
The neuron-restrictive silencer factor (NRSF): a coordinate repressor of multiple neuron-specific genes
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
NAS
retrieved
1 January 2018
stated in
Neuronal restrictive silencing factor silencing induces human amniotic fluid-derived stem cells differentiation into insulin-producing cells
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IMP
retrieved
1 January 2018
stated in
NRSF silencing induces neuronal differentiation of human mesenchymal stem cells
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IMP
retrieved
1 January 2018
stated in
REST is a hypoxia-responsive transcriptional repressor
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IMP
retrieved
1 January 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IEA
retrieved
1 January 2018
stated in
REST: a mammalian silencer protein that restricts sodium channel gene expression to neurons
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IDA
retrieved
1 January 2018
stated in
Dual role of NRSF/REST in activation and repression of the glucocorticoid response
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IDA
retrieved
1 January 2018
stated in
Regulation of aldosterone and cortisol production by the transcriptional repressor neuron restrictive silencer factor
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IDA
retrieved
1 January 2018
stated in
The co-repressor mSin3A is a functional component of the REST-CoREST repressor complex
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IDA
retrieved
1 January 2018
stated in
CoREST: a functional corepressor required for regulation of neural-specific gene expression
GOA
curator
UniProt
UniProt protein ID
Q13127
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13127
determination method
IDA
Gene Atlas image
PBB GE REST 212920 at fs.png
732 × 530; 11 KB
0 references

Identifiers

 
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