Proprotein convertase subtilisin/kexin type 2 (Q7250440)

Peptidase S8/S53 domain superfamily

1 reference

Galactose-binding-like domain superfamily

1 reference

Peptidase S8, pro-domain superfamily

1 reference

Peptidase S8, pro-domain, protein family

1 reference

Kexin/furin catalytic domain, protein family

1 reference

Peptidase S8, subtilisin, Ser-active site, protein family

1 reference

P domain family

1 reference

Peptidase S8, subtilisin, Asp-active site, protein family

1 reference

Subtilase

1 reference

Peptidase S8, subtilisin, His-active site, protein family

1 reference

1 reference

13 November 2019

1 reference

13 November 2019

endopeptidase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

1 reference

8 April 2019

7B2 is a neuroendocrine chaperone that transiently interacts with prohormone convertase PC2 in the secretory pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

serine-type peptidase activity

IPI

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

serine-type endopeptidase activity

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16519&geneProductId=UniProtKB:P16519

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16519&geneProductId=UniProtKB:P16519

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16519&geneProductId=UniProtKB:P16519

24 April 2018

Differences between the catalytic properties of recombinant human PC2 and endogenous rat PC2

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16519&geneProductId=UniProtKB:P16519

protein-containing complex binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

serine-type endopeptidase activity

3 references

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16519&geneProductId=UniProtKB:P16519

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16519&geneProductId=UniProtKB:P16519

7 November 2018

Differences between the catalytic properties of recombinant human PC2 and endogenous rat PC2

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16519&geneProductId=UniProtKB:P16519

serine-type endopeptidase activity

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

8 April 2019

Differences between the catalytic properties of recombinant human PC2 and endogenous rat PC2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

1 reference

7 November 2018

Calcium- and pH-dependent aggregation and membrane association of the precursor of the prohormone convertase PC2

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16519&geneProductId=UniProtKB:P16519

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16519&geneProductId=UniProtKB:P16519

secretory granule lumen

1 reference

24 April 2018

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

3 references

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16519&geneProductId=UniProtKB:P16519

7 November 2018

Functional analysis of PCSK2 coding variants: A founder effect in the Old Order Amish population

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16519&geneProductId=UniProtKB:P16519

7 November 2018

Mutations within the propeptide, the primary cleavage site or the catalytic site, or deletion of C-terminal sequences, prevents secretion of proPC2 from transfected COS-7 cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16519&geneProductId=UniProtKB:P16519

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

intracellular membrane-bounded organelle

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

8 April 2019

Functional analysis of PCSK2 coding variants: A founder effect in the Old Order Amish population

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

8 April 2019

Mutations within the propeptide, the primary cleavage site or the catalytic site, or deletion of C-terminal sequences, prevents secretion of proPC2 from transfected COS-7 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16519&geneProductId=UniProtKB:P16519

1 reference

8 April 2019

Differences between the catalytic properties of recombinant human PC2 and endogenous rat PC2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

protein autoprocessing

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

nervous system development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

8 April 2019

Differences between the catalytic properties of recombinant human PC2 and endogenous rat PC2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

peptide hormone processing

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

8 April 2019

Functional analysis of PCSK2 coding variants: A founder effect in the Old Order Amish population

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519

Peptidase S8, subtilisin, Asp-active site

IBA

has part(s)

1 reference

Peptidase S8, pro-domain

1 reference

P domain

1 reference

peptidase S8, subtilisin, His-active site

1 reference

Peptidase S8, subtilisin, Ser-active site

1 reference

peptidase S8/S53 domain

1 reference

Kexin/furin catalytic domain

1 reference

D08.811.277.656.300.760.646

Identifiers

MeSH descriptor ID

D045706

subject named as

Proprotein Convertase 2

0 references

MeSH tree code

0 references

D08.811.277.656.837.562

0 references

D08.811.277.656.959.350.646

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

inferred by common MeSH mappings on source and on Wikidata