Quantitative structure-activity analysis correlating Ras/Raf interaction in vitro to Raf activation in vivo (Q71011188)

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15 October 2019

title

Quantitative structure-activity analysis correlating Ras/Raf interaction in vitro to Raf activation in vivo (English)

1 reference

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15 October 2019

author name string

Block C

1

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15 October 2019

Janknecht R

2

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15 October 2019

Herrmann C

3

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15 October 2019

Nassar N

4

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15 October 2019

Wittinghofer A

5

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15 October 2019

publication date

1 March 1996

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Nature structural biology

15 October 2019

published in

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15 October 2019

volume

3

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15 October 2019

issue

3

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15 October 2019

page(s)

244-251

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The ins and outs of Raf kinases

15 October 2019

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

GTP-dependent association of Raf-1 with Ha-Ras: identification of Raf as a target downstream of Ras in mammalian cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

Complex formation between RAS and RAF and other protein kinases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

Mammalian Ras interacts directly with the serine/threonine kinase Raf

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

Signal transduction pathways involving Ras. Mini review

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

Critical binding and regulatory interactions between Ras and Raf occur through a small, stable N-terminal domain of Raf and specific Ras effector residues

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

Chemical shift assignments and folding topology of the Ras-binding domain of human Raf-1 as determined by heteronuclear three-dimensional NMR spectroscopy.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

Quantitative analysis of the complex between p21ras and the Ras-binding domain of the human Raf-1 protein kinase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

Protein modules and signalling networks

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

Serum-, TPA-, and Ras-induced expression from Ap-1/Ets-driven promoters requires Raf-1 kinase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

Activation of Raf as a result of recruitment to the plasma membrane

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

The effector interactions of p21ras

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

A single amino acid change in Raf-1 inhibits Ras binding and alters Raf-1 function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

Reversal of Raf-1 activation by purified and membrane-associated protein phosphatases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

Regulation of Raf-1 and Raf-1 mutants by Ras-dependent and Ras-independent mechanisms in vitro

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

The MAPK signaling cascade

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

Signal integration at the c-fos promoter

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

Structure of the guanine-nucleotide-binding domain of the Ha-ras oncogene product p21 in the triphosphate conformation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

Identification of small clusters of divergent amino acids that mediate the opposing effects of ras and Krev-1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

Identification of amino acid residues required for Ras p21 target activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

A hot spot of binding energy in a hormone-receptor interface

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

Pharmaceutical research in molecular oncology

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

Solution structure of the Ras-binding domain of c-Raf-1 and identification of its Ras interaction surface

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

Comparison of a structural and a functional epitope

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

High resolution functional analysis of antibody-antigen interactions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

Thermodynamic analysis of an antibody functional epitope

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

Rational design of receptor-specific variants of human growth hormone

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

Two distinct Raf domains mediate interaction with Ras

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

Ras-effector interactions, the problem of specificity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

Switching to Rac and Rho.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

Improved method for PCR-mediated site-directed mutagenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

Functional expression and growth factor activation of an epitope-tagged p44 mitogen-activated protein kinase, p44mapk

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

inferred from DOI database lookup

7 January 2021

based on heuristic

Activation of ternary complex factor Elk-1 by MAP kinases

1 reference

https://api.crossref.org/works/10.1038%2FNSB0396-244

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NSB0396-244

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8605626%20AND%20SRC:MED&resulttype=core&format=json

15 October 2019

1 reference