Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF (Q7075410)

Immunoglobulin-like fold

1 reference

Protein kinase-like domain superfamily

1 reference

Fibronectin type III superfamily

1 reference

Immunoglobulin-like domain superfamily

1 reference

Dbl homology (DH) domain superfamily

1 reference

PH-like domain superfamily

1 reference

Immunoglobulin I-set, protein family

1 reference

Fibronectin type III, protein family

1 reference

pleckstrin homology domain, protein family

1 reference

Immunoglobulin subtype, protein family

1 reference

Immunoglobulin V-set domain, protein family

1 reference

Dbl homology (DH) domain, protein family

1 reference

SH3 domain, protein family

1 reference

Immunoglobulin subtype 2, protein family

1 reference

Protein kinase domain, protein family

1 reference

immunoglobulin-like domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

IQ motif, EF-hand binding site, protein family

1 reference

Tyrosine-protein kinase, active site, protein family

1 reference

Obscurin, SH3 domain, protein family

1 reference

Serine/threonine-protein kinase, active site, protein family

1 reference

Obscurin targets ankyrin-B and protein phosphatase 2A to the cardiac M-line

1 reference

5 December 2018

1 reference

5 December 2018

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

protein kinase activity

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

protein serine/threonine kinase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

structural constituent of muscle

1 reference

8 April 2019

The complete gene sequence of titin, expression of an unusual approximately 700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

2 references

1 reference

8 April 2019

The complete gene sequence of titin, expression of an unusual approximately 700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

6 references

8 April 2019

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

8 April 2019

Molecular interactions with obscurin are involved in the localization of muscle-specific small ankyrin1 isoforms to subcompartments of the sarcoplasmic reticulum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

8 April 2019

Molecular basis of the head-to-tail assembly of giant muscle proteins obscurin-like 1 and titin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

8 April 2019

Structural insight into M-band assembly and mechanics from the titin-obscurin-like-1 complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

8 April 2019

Obscurin, a giant sarcomeric Rho guanine nucleotide exchange factor protein involved in sarcomere assembly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

8 April 2019

Binding of an ankyrin-1 isoform to obscurin suggests a molecular link between the sarcoplasmic reticulum and myofibrils in striated muscles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

guanyl-nucleotide exchange factor activity

IPI

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q5VST9&geneProductId=UniProtKB:Q5VST9

phosphatidylinositol-4,5-bisphosphate binding

1 reference

8 April 2019

Novel obscurins mediate cardiomyocyte adhesion and size via the PI3K/AKT/mTOR signaling pathway.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

phosphatidylinositol-3,4,5-trisphosphate binding

1 reference

8 April 2019

Novel obscurins mediate cardiomyocyte adhesion and size via the PI3K/AKT/mTOR signaling pathway.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

phosphatidylinositol-5-phosphate binding

1 reference

8 April 2019

Novel obscurins mediate cardiomyocyte adhesion and size via the PI3K/AKT/mTOR signaling pathway.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

phosphatidylinositol-3-phosphate binding

1 reference

8 April 2019

Novel obscurins mediate cardiomyocyte adhesion and size via the PI3K/AKT/mTOR signaling pathway.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

phosphatidylinositol-3,4-bisphosphate binding

1 reference

8 April 2019

Novel obscurins mediate cardiomyocyte adhesion and size via the PI3K/AKT/mTOR signaling pathway.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

phosphatidylinositol-4-phosphate binding

1 reference

8 April 2019

Novel obscurins mediate cardiomyocyte adhesion and size via the PI3K/AKT/mTOR signaling pathway.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

1 reference

8 April 2019

The complete gene sequence of titin, expression of an unusual approximately 700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

3 references

8 April 2019

Obscurin targets ankyrin-B and protein phosphatase 2A to the cardiac M-line

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

8 April 2019

The complete gene sequence of titin, expression of an unusual approximately 700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

Obscurin targets ankyrin-B and protein phosphatase 2A to the cardiac M-line

biological process

sarcomere organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

regulation of Rho protein signal transduction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

multicellular organism development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

positive regulation of apoptotic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

protein phosphorylation

1 reference

8 April 2019

protein localization to M-band

1 reference

8 April 2019

Obscurin targets ankyrin-B and protein phosphatase 2A to the cardiac M-line

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

regulation of small GTPase mediated signal transduction

ISS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

G protein-coupled receptor signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VST9

IQ motif, EF-hand binding site

has part(s)

1 reference

immunoglobulin-like domain

1 reference

fibronectin type III

1 reference

protein kinase, ATP binding site

1 reference

pleckstrin homology domain

1 reference

protein kinase domain

1 reference

immunoglobulin subtype

1 reference

immunoglobulin I-set

1 reference

serine/threonine-protein kinase, active site

1 reference

tyrosine-protein kinase, active site

1 reference

immunoglobulin subtype 2

1 reference

immunoglobulin V-set domain

1 reference

Dbl homology (DH) domain

1 reference

Obscurin, SH3 domain

1 reference

SH3 domain

1 reference

Identifiers

1 reference

7 December 2018

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7 December 2018

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7 December 2018

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7 December 2018

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7 December 2018

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7 December 2018

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7 December 2018

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7 December 2018

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7 December 2018

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7 December 2018

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7 December 2018

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7 December 2018

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7 December 2018

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7 December 2018

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7 December 2018

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7 December 2018

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7 December 2018

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7 December 2018

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7 December 2018

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7 December 2018

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7 December 2018

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5 December 2018

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1 August 2016

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1 August 2016

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1 August 2016

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1 August 2016

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1 August 2016

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1 August 2016

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1 August 2016

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1 August 2016

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1 August 2016

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1 August 2016

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1 August 2016

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1 August 2016