MutS homolog 6 (Q6717781)

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mammalian protein found in Homo sapiens
  • mutS protein homolog 6
  • G/T mismatch-binding protein
  • GTMBP
  • mutS-alpha 160 kDa subunit
  • DNA mismatch repair protein Msh6
  • sperm-associated protein
  • MSH6
  • GTBP
  • p160
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Language Label Description Also known as
English
MutS homolog 6
mammalian protein found in Homo sapiens
  • mutS protein homolog 6
  • G/T mismatch-binding protein
  • GTMBP
  • mutS-alpha 160 kDa subunit
  • DNA mismatch repair protein Msh6
  • sperm-associated protein
  • MSH6
  • GTBP
  • p160

Statements

molecular function
protein binding
determination method
IPI
12 references
retrieved
9 May 2019
stated in
Functional interaction of proliferating cell nuclear antigen with MSH2-MSH6 and MSH2-MSH3 complexes
GOA
curator
UniProt
UniProt protein ID
P52701
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52701
determination method
IPI
retrieved
9 May 2019
stated in
Analysis of the human MutLalpha.MutSalpha complex
GOA
curator
UniProt
UniProt protein ID
P52701
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52701
determination method
IPI
retrieved
9 May 2019
stated in
MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation
GOA
curator
UniProt
UniProt protein ID
P52701
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52701
determination method
IPI
retrieved
9 May 2019
stated in
hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6
GOA
curator
UniProt
UniProt protein ID
P52701
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52701
determination method
IPI
retrieved
9 May 2019
stated in
Identification of factors interacting with hMSH2 in the fetal liver utilizing the yeast two-hybrid system. In vivo interaction through the C-terminal domains of hEXO1 and hMSH2 and comparative expression analysis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52701
determination method
IPI
retrieved
9 May 2019
stated in
Interactions of human hMSH2 with hMSH3 and hMSH2 with hMSH6: examination of mutations found in hereditary nonpolyposis colorectal cancer
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52701
determination method
IPI
retrieved
9 May 2019
stated in
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52701
determination method
IPI
retrieved
9 May 2019
stated in
A human interactome in three quantitative dimensions organized by stoichiometries and abundances
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52701
determination method
IPI
retrieved
9 May 2019
stated in
The nucleotide binding dynamics of human MSH2-MSH3 are lesion dependent
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52701
determination method
IPI
retrieved
9 May 2019
stated in
Analysis of the human MutLalpha.MutSalpha complex
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52701
determination method
IPI
retrieved
9 May 2019
stated in
Human MutY homolog, a DNA glycosylase involved in base excision repair, physically and functionally interacts with mismatch repair proteins human MutS homolog 2/human MutS homolog 6
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52701
determination method
IPI
retrieved
9 May 2019
stated in
hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52701
determination method
IPI
mismatched DNA binding
determination method
IBA
IDA
IEA
6 references
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52701
determination method
IEA
retrieved
9 May 2019
stated in
The histone mark H3K36me3 regulates human DNA mismatch repair through its interaction with MutSα
GOA
curator
UniProt
UniProt protein ID
P52701
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52701
determination method
IDA
retrieved
9 May 2019
stated in
hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52701
determination method
IDA
retrieved
9 May 2019
stated in
Human MutY homolog, a DNA glycosylase involved in base excision repair, physically and functionally interacts with mismatch repair proteins human MutS homolog 2/human MutS homolog 6
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52701
determination method
IDA
retrieved
9 May 2019
stated in
Activation of human MutS homologs by 8-oxo-guanine DNA damage
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52701
determination method
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52701
determination method
IBA
cell component
biological process
DNA mismatch repair
determination method
IDA
IGI
TAS
IMP
IEA
7 references
retrieved
27 February 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P52701&geneProductId=UniProtKB:P52701
determination method
TAS
retrieved
27 February 2018
stated in
Mutation of MSH3 in endometrial cancer and evidence for its functional role in heteroduplex repair
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P52701&geneProductId=UniProtKB:P52701
determination method
IMP
retrieved
27 February 2018
stated in
Ribonucleotides misincorporated into DNA act as strand-discrimination signals in eukaryotic mismatch repair
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P52701&geneProductId=UniProtKB:P52701
determination method
IGI
retrieved
27 February 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P52701&geneProductId=UniProtKB:P52701
determination method
IEA
retrieved
27 February 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P52701&geneProductId=UniProtKB:P52701
determination method
IEA
retrieved
27 February 2018
stated in
The histone mark H3K36me3 regulates human DNA mismatch repair through its interaction with MutSα
GOA
curator
UniProt
UniProt protein ID
P52701
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P52701&geneProductId=UniProtKB:P52701
determination method
IDA
retrieved
27 February 2018
stated in
Multiple mutations and frameshifts are the hallmark of defective hPMS2 in pZ189-transfected human tumor cells
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P52701&geneProductId=UniProtKB:P52701
determination method
IDA
DNA mismatch repair
determination method
IBA
IDA
IEA
IGI
IMP
TAS
8 references
retrieved
9 May 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52701
determination method
TAS
retrieved
9 May 2019
stated in
Mutation of MSH3 in endometrial cancer and evidence for its functional role in heteroduplex repair
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52701
determination method
IMP
retrieved
9 May 2019
stated in
Ribonucleotides misincorporated into DNA act as strand-discrimination signals in eukaryotic mismatch repair
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52701
determination method
IGI
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52701
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52701
determination method
IEA
retrieved
9 May 2019
stated in
The histone mark H3K36me3 regulates human DNA mismatch repair through its interaction with MutSα
GOA
curator
UniProt
UniProt protein ID
P52701
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52701
determination method
IDA
retrieved
9 May 2019
stated in
Multiple mutations and frameshifts are the hallmark of defective hPMS2 in pZ189-transfected human tumor cells
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52701
determination method
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52701
determination method
IBA
Gene Atlas image
PBB GE MSH6 202911 at fs.png
732 × 530; 12 KB
0 references

Identifiers

 
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                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q6717781&oldid=2022909144"