MAS1 proto-oncogene, G protein-coupled receptor (Q6714499)

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mammalian protein found in Homo sapiens

• proto-oncogene Mas
• MAS1
• Mas-related G protein-coupled receptor A
• MAS1 oncogene

edit

Language	Label	Description	Also known as
English	MAS1 proto-oncogene, G protein-coupled receptor	mammalian protein found in Homo sapiens	proto-oncogene Mas MAS1 Mas-related G protein-coupled receptor A MAS1 oncogene

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P04201

part of

proto-oncogene Mas

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P04201

Mas-related G protein-coupled receptor family

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P04201

GPCR, rhodopsin-like, 7TM, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P04201

encoded by

MAS1

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P04201

molecular function

G protein-coupled receptor activity

determination method

IDA

IEA

TAS

4 references

retrieved

27 March 2018

stated in

The mas oncogene encodes an angiotensin receptor

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04201&geneProductId=UniProtKB:P04201

determination method

TAS

retrieved

27 March 2018

stated in

GOA

curator

UniProt

UniProt protein ID

P04201

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04201&geneProductId=UniProtKB:P04201

determination method

IEA

retrieved

27 March 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04201&geneProductId=UniProtKB:P04201

determination method

IEA

retrieved

27 March 2018

stated in

Up-regulation of the angiotensin II type 1 receptor by the MAS proto-oncogene is due to constitutive activation of Gq/G11 by MAS

GOA

curator

UniProt

UniProt protein ID

P04201

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04201&geneProductId=UniProtKB:P04201

determination method

IDA

angiotensin type II receptor activity

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

The mas oncogene encodes an angiotensin receptor

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

TAS

peptide binding

determination method

ISS

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04201

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

ISS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IEA

signal transducer activity

determination method

IEA

1 reference

retrieved

27 March 2018

stated in

GOA

curator

UniProt

UniProt protein ID

P04201

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04201&geneProductId=UniProtKB:P04201

determination method

IEA

peptide hormone binding

determination method

IEA

1 reference

retrieved

27 March 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04201&geneProductId=UniProtKB:P04201

determination method

IEA

angiotensin receptor activity

determination method

ISS

IEA

2 references

retrieved

27 March 2018

stated in

GOA

curator

UniProt

UniProt protein ID

P04201

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04201&geneProductId=UniProtKB:P04201

determination method

ISS

retrieved

27 March 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04201&geneProductId=UniProtKB:P04201

determination method

IEA

protein binding

determination method

IPI

1 reference

retrieved

8 April 2019

stated in

G protein-coupled receptors directly bind filamin A with high affinity and promote filamin phosphorylation

GOA

curator

UniProt

UniProt protein ID

P04201

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IPI

angiotensin receptor activity

determination method

IBA

IEA

ISS

3 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04201

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

ISS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IBA

G protein-coupled receptor activity

determination method

IBA

IDA

IEA

TAS

5 references

retrieved

8 April 2019

stated in

The mas oncogene encodes an angiotensin receptor

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04201

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IEA

retrieved

8 April 2019

stated in

Up-regulation of the angiotensin II type 1 receptor by the MAS proto-oncogene is due to constitutive activation of Gq/G11 by MAS

GOA

curator

UniProt

UniProt protein ID

P04201

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IBA

cell component

integral component of membrane

determination method

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04201

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IEA

membrane

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04201

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IEA

plasma membrane

determination method

IDA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04201

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IEA

retrieved

8 April 2019

stated in

Up-regulation of the angiotensin II type 1 receptor by the MAS proto-oncogene is due to constitutive activation of Gq/G11 by MAS

GOA

curator

UniProt

UniProt protein ID

P04201

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IDA

integral component of plasma membrane

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

The mas oncogene encodes an angiotensin receptor

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

TAS

cell surface

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IEA

intracellular anatomical structure

determination method

IEA

1 reference

retrieved

10 September 2018

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04201&geneProductId=UniProtKB:P04201

determination method

IEA

biological process

negative regulation of protein phosphorylation

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IEA

G protein-coupled receptor signaling pathway

determination method

TAS

IEA

4 references

retrieved

27 March 2018

stated in

The mas oncogene encodes an angiotensin receptor

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04201&geneProductId=UniProtKB:P04201

determination method

TAS

retrieved

27 March 2018

stated in

GOA

curator

UniProt

UniProt protein ID

P04201

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04201&geneProductId=UniProtKB:P04201

determination method

IEA

retrieved

27 March 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04201&geneProductId=UniProtKB:P04201

determination method

IEA

retrieved

27 March 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04201&geneProductId=UniProtKB:P04201

determination method

IEA

male gonad development

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IEA

positive regulation of inositol phosphate biosynthetic process

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IEA

angiotensin-activated signaling pathway

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IEA

anatomical structure morphogenesis

determination method

TAS

1 reference

retrieved

1 January 2018

stated in

The MAS proto-oncogene is not imprinted in humans

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

TAS

response to peptide hormone

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IEA

activation of NF-kappaB-inducing kinase activity

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IEA

protein kinase C signaling

determination method

IMP

1 reference

retrieved

8 April 2019

stated in

Up-regulation of the angiotensin II type 1 receptor by the MAS proto-oncogene is due to constitutive activation of Gq/G11 by MAS

GOA

curator

UniProt

UniProt protein ID

P04201

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IMP

response to activity

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IEA

response to gonadotropin

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IEA

positive regulation of DNA replication

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IEA

cellular response to peptide hormone stimulus

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IEA

spermatogenesis

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IEA

positive regulation of cell population proliferation

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IEA

regulation of inflammatory response

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IEA

cell population proliferation

determination method

TAS

1 reference

retrieved

1 January 2018

stated in

The mas oncogene encodes an angiotensin receptor

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

TAS

hippocampus development

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IEA

signal transduction

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04201

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IEA

G protein-coupled receptor signaling pathway

determination method

IBA

IEA

TAS

5 references

retrieved

8 April 2019

stated in

The mas oncogene encodes an angiotensin receptor

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04201

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04201

determination method

IBA

physically interacts with

angiotensin 1-7

object has role

agonist

1 reference

stated in

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL3545347

Gene Atlas image

PBB GE MAS1 208210 at fs.png
732 × 530; 12 KB

0 references

has part(s)

GPCR, rhodopsin-like, 7TM

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P04201

Identifiers

RefSeq protein ID

NP_002368

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

4142

NP_001353633

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

4142

UniProt protein ID

P04201

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P04201

Ensembl protein ID

ENSP00000252660

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000252660

ENSP00000501180

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000501180

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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