Abnormal TNF activity in Timp3 −/− mice leads to chronic hepatic inflammation and failure of liver regeneration (Q59276614)

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31 December 2019

title

Abnormal TNF activity in Timp3-/- mice leads to chronic hepatic inflammation and failure of liver regeneration (English)

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31 December 2019

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Barbara Mary Fingleton

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31 December 2019

author name string

Fazilat F Mohammed

1

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David S Smookler

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Suzanne E M Taylor

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Zamaneh Kassiri

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Otto H Sanchez

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Jane L English

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Lynn M Matrisian

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Billie Au

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Wen-Chen Yeh

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Rama Khokha

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language of work or name

English

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publication date

22 August 2004

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31 December 2019

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volume

36

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issue

9

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31 December 2019

page(s)

969-977

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https://scigraph.springernature.com/pub.10.1038/ng1413

31 December 2019

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cites work

Mutations in the tissue inhibitor of metalloproteinases-3 (TIMP3) in patients with Sorsby's fundus dystrophy

1 reference

Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3).

21 January 2018

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Accelerated apoptosis in the Timp-3-deficient mammary gland

21 January 2018

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Full-length and N-TIMP-3 display equal inhibitory activities toward TNF-alpha convertase

21 January 2018

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A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells

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Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha

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Adamalysins. A family of metzincins including TNF-alpha converting enzyme (TACE).

21 January 2018

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TNF-alpha-converting enzyme cleaves the macrophage colony-stimulating factor receptor in macrophages undergoing activation.

21 January 2018

1 reference

Membrane-anchored CD40 Is Processed by the Tumor Necrosis Factor-α-converting Enzyme

21 January 2018

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TACE/ADAM17 processing of EGFR ligands indicates a role as a physiological convertase

21 January 2018

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Signalling pathways of the TNF superfamily: a double-edged sword

21 January 2018

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TNF-R1 signaling: a beautiful pathway

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Processing of tumour necrosis factor-α precursor by metalloproteinases

21 January 2018

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Regulation of tumour necrosis factor-alpha processing by a metalloproteinase inhibitor

21 January 2018

1 reference

Expression analysis of the entire MMP and TIMP gene families during mouse tissue development.

21 January 2018

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Interleukin-6 from intrahepatic cells of bone marrow origin is required for normal murine liver regeneration.

21 January 2018

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A phase I study of oral BMS-275291, a novel nonhydroxamate sheddase-sparing matrix metalloproteinase inhibitor, in patients with advanced or metastatic cancer

21 January 2018

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Membrane-type matrix metalloproteinases 1 and 2 exhibit broad-spectrum proteolytic capacities comparable to many matrix metalloproteinases

21 January 2018

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Membrane type 4 matrix metalloproteinase (MMP17) has tumor necrosis factor-alpha convertase activity but does not activate pro-MMP2.

21 January 2018

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Matrix metalloproteinase-7-dependent release of tumor necrosis factor-alpha in a model of herniated disc resorption

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NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

21 January 2018

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Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B

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Initiation of liver growth by tumor necrosis factor: deficient liver regeneration in mice lacking type I tumor necrosis factor receptor

21 January 2018

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Grade and stage in chronic hepatitis

21 January 2018

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Chronic active hepatitis in transgenic mice expressing interferon-gamma in the liver

21 January 2018

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Life-or-death decisions

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The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation

21 January 2018

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PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines

21 January 2018

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Tumour necrosis factor-alpha stimulates expression of TNF-alpha converting enzyme in endothelial cells

21 January 2018

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Noncleavable transmembrane mouse tumor necrosis factor-alpha (TNFalpha) mediates effects distinct from those of wild-type TNFalpha in vitro and in vivo

21 January 2018

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Membrane-bound TNF supports secondary lymphoid organ structure but is subservient to secreted TNF in driving autoimmune inflammation.

21 January 2018

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Points of control in inflammation

21 January 2018

1 reference

Generation and functional characterization of a clonal murine periportal Kupffer cell line from H-2Kb -tsA58 mice.

21 January 2018

1 reference

Sorsby's fundus dystrophy tissue inhibitor of metalloproteinases-3 (TIMP-3) mutants have unimpaired matrix metalloproteinase inhibitory activities, but affect cell adhesion to the extracellular matrix

21 January 2018

1 reference

Expression of Sorsby's fundus dystrophy mutations in human retinal pigment epithelial cells reduces matrix metalloproteinase inhibition and may promote angiogenesis

21 January 2018

1 reference

An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice

21 January 2018

1 reference

A continuous fluorimetric assay for tumor necrosis factor-alpha converting enzyme

21 January 2018

1 reference

Development of a novel fluorogenic proteolytic beacon for in vivo detection and imaging of tumour-associated matrix metalloproteinase-7 activity

21 January 2018

1 reference

TNF-alpha converting enzyme (TACE) is inhibited by TIMP-3

21 January 2018

1 reference

7 January 2021

An essential role for ectodomain shedding in mammalian development

1 reference

7 January 2021

Expression patterns of matrix metalloproteinases and their inhibitors in parenchymal and non-parenchymal cells of rat liver: regulation by TNF-alpha and TGF-beta1

1 reference

7 January 2021

Targeted mutation of TNF receptor I rescues the RelA-deficient mouse and reveals a critical role for NF-kappa B in leukocyte recruitment

1 reference

7 January 2021

Impaired On/Off Regulation of TNF Biosynthesis in Mice Lacking TNF AU-Rich Elements

1 reference

7 January 2021

Identifiers

DOI

10.1038/NG1413

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15322543%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

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