HL-60 (Q5630035)

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cell line

HL 60
HL.60 HL60
Human Leukemia-60

Language	Label	Description	Also known as
English	HL-60	cell line	HL 60 HL.60 HL60 Human Leukemia-60

Statements

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Cellosaurus release 44

10 January 2023

cancer cell line

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Cellosaurus release 44

10 January 2023

Anaplasma phagocytophilum cultured in human promyelocytic cell line HL-60.jpg
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described by source

Characterization of the continuous, differentiating myeloid cell line (HL-60) from a patient with acute promyelocytic leukemia

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Continuous growth and differentiation of human myeloid leukaemic cells in suspension culture

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Expression of the polymorphic human DNA repair gene XRCC1 does not correlate with radiosensitivity in the cells of human head and neck tumor cell lines

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Lineage infidelity of a human myelogenous leukemia cell line.

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Cell surface antigens of human ovarian and endometrial carcinoma defined by mouse monoclonal antibodies

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10 January 2023

Human myeloid leukemia cell lines: a review

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Homozygous deletions of the CDKN2 (MTS1/p16ink4) gene in cell lines established from children with acute lymphoblastic leukemia.

1 reference

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DNA double-strand break rejoining deficiency in TK6 and other human B-lymphoblast cell lines

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Use of the comet test in the evaluation of multidrug resistance of human cell lines

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The induction of apoptosis and cell cycle arrest by arsenic trioxide in lymphoid neoplasms

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Expression of the TCL1 gene at 14q32 in B-cell malignancies but not in adult T-cell leukemia

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Identification of microsatellite instability and mismatch repair gene mutations in breast cancer cell lines.

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Gene expression profiling of leukemic cell lines reveals conserved molecular signatures among subtypes with specific genetic aberrations.

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JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders

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Mutation analysis of 24 known cancer genes in the NCI-60 cell line set.

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A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers

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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

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The analysis of N-glycans of cell membrane proteins from human hematopoietic cell lines reveals distinctions in their pattern

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Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms

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High resolution copy number variation data in the NCI-60 cancer cell lines from whole genome microarrays accessible through CellMiner

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A comprehensive transcriptional portrait of human cancer cell lines

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A mass spectrometric-derived cell surface protein atlas

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Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies

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A landscape of pharmacogenomic interactions in cancer.

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Characterization of Human Cancer Cell Lines by Reverse-phase Protein Arrays

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Retinoic acid-induced granulocytic differentiation of HL-60 myeloid leukemia cells is mediated directly through the retinoic acid receptor (RAR-alpha).

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Expression of leukocyte common antigen (CD45) on various human leukemia/lymphoma cell lines

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Intracellular distribution and pharmacokinetics of daunorubicin in anthracycline-sensitive and -resistant HL-60 cells

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Major deletions in the gene encoding the p53 tumor antigen cause lack of p53 expression in HL-60 cells

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Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay

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HL-60 cell line was derived from a patient with FAB-M2 and not FAB-M3

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Isolation and characterization of an anthracycline-resistant human leukemic cell line.

1 reference

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Induction of differentiation in a human promyelocytic leukemic cell line (HL-60) *1Production of granule proteins

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A blast subclone of the HL-60 human promyelocytic cell line

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10 January 2023

[Serum-free culture for leukemia cells]

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Cell surface c-kit receptors in human leukemia cell lines and pediatric leukemia: selective preservation of c-kit expression on megakaryoblastic cell lines during adaptation to in vitro culture

1 reference

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Transfection of wild-type but not mutant p53 induces early monocytic differentiation in HL60 cells and increases their sensitivity to stress

1 reference

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Prolonged weightlessness affects promyelocytic multidrug resistance

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Frameshift mutations of the hMSH6 gene in human leukemia cell lines.

1 reference

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Restoration of wild-type p53 activity in p53-null HL-60 cells confers multidrug sensitivity.

1 reference

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Mutations of the BRAF gene in human cancer

1 reference

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Comparison of the complete mtDNA genome sequences of human cell lines--HL-60 and GM10742A--from individuals with pro-myelocytic leukemia and leber hereditary optic neuropathy, respectively, and the inclusion of HL-60 in the NIST human mitochondrial

1 reference

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Signatures of mutation and selection in the cancer genome

1 reference

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Mechanisms of resistance to azacitidine in human leukemia cell lines.

1 reference

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Profiling the B/T cell receptor repertoire of lymphocyte derived cell lines

1 reference

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Establishment of a ΔF508-CF promyelocytic cell line for cystic fibrosis research and drug screening

1 reference

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An Interactive Resource to Probe Genetic Diversity and Estimated Ancestry in Cancer Cell Lines

1 reference

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Next-generation characterization of the Cancer Cell Line Encyclopedia

1 reference

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The LL-100 panel: 100 cell lines for blood cancer studies.

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Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anti-cancer drug resistance

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Differential expression of the amv gene in human hematopoietic cells

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Hh/Gli antagonist in acute myeloid leukemia with CBFA2T3-GLIS2 fusion gene

1 reference

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Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines

1 reference

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Corrigendum to: Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines Leukemia Research 24 (2000), 255-262

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Screening human cell lines for viral infections applying RNA-Seq data analysis

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Growth study of lactate and ammonia double-resistant clones of HL-60 cells

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Isoenzyme studies in human leukemia-lymphoma cell lines--1. Carboxylic esterase

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Isoenzyme studies in human leukemia-lymphoma cell lines--III. beta-Hexosaminidase (E.C. 3.2.1.30).

1 reference

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Isoenzyme studies in human leukemia-lymphoma cells lines--II. Acid phosphatase

1 reference

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The HL-60 promyelocytic leukemia cell line: proliferation, differentiation, and cellular oncogene expression.

1 reference

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The novel BET bromodomain inhibitor BI 894999 represses super-enhancer-associated transcription and synergizes with CDK9 inhibition in AML.

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established from medical condition

adult acute myeloid leukemia

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derived from organism type

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http://purl.obolibrary.org/obo/BTO_0000738

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http://purl.obolibrary.org/obo/EFO_0002793

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http://purl.obolibrary.org/obo/CLO_0003775

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http://purl.obolibrary.org/obo/CLO_0050972

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Commons category

HL-60 cells

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Identifiers

MeSH descriptor ID

1 reference

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Cell Line Ontology ID

1 reference

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1 reference

Cellosaurus release 44

10 January 2023

1 reference

Cellosaurus release 44

10 January 2023

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Microsoft Academic ID

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1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(5 entries)

enwiki HL60
eswiki Célula HL-60
extwiki Célula HL-60
jawiki HL60細胞
zhwiki HL-60

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(1 entry)

commonswiki Category:HL-60 cells

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